Roles of vascular endothelial growth factor, Angiopoietin 1, and Angiopoietin 2 in nasal polyp

Laryngoscope

Volumn 119, Issue 2, 2009, Pages 409-413

  Park, Seong Kook ^a   Kim, Hyeong In ^a   Yang, Young Il ^a  

^a Inje University College of Medicine   (South Korea)

Author keywords

Angiopoietin 1; Angiopoietin 2; Dexamethasone; Nasal polyp; Organ culture; Vascular endothelial growth factor

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; DEXAMETHASONE; VASCULOTROPIN; GLUCOCORTICOID; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; INFLAMMATORY CELL; NOSE MUCOSA; NOSE POLYP; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; TISSUE CULTURE; TURBINATE; VASCULAR ENDOTHELIUM; ANALYSIS OF VARIANCE; CULTURE TECHNIQUE; METABOLISM;

ANALYSIS OF VARIANCE; ANGIOPOIETIN-1; ANGIOPOIETIN-2; CELL CULTURE TECHNIQUES; DEXAMETHASONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUCOCORTICOIDS; HUMANS; NASAL MUCOSA; NASAL POLYPS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 63249110109     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.20085     Document Type: Article

References (18)

1. Carmeliet P. Manipulating angiogenesis in medicine. J Intern Med 2004; 255:538-561.
2. Connolly DT, Heuvelman DM, Nelson R., et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989; 84:1470-1478.
3. Maisonpierre PC, Suri C., Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 1997; 277:55-60.
4. Iwama A., Hamaguchi I., Hashiyama M., et al. Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells. Biochem Biophys Res Commun 1993; 195:301-309.
5. Teichert-Kuliszewska K., Maisonpierre PC, Jones N., et al. Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2. Cardiovasc Res 2001; 49:659-670.
6. Pawankar R. Nasal polyposis: an update. Curr Opin Allergy Clin Immunol 2003; 3:1-6.
7. Halmilos DL, Thawley SE, Kramper MA, et al. Effect of intranasal fluticasone on cellular infiltration, endothelial adhesion molecule expression, and proinflammatory cytokine mRNA in nasal polyp disease. J Allergy Clin Immunol 1999; 103:79-87.
8. Coste A., Brugel L., Maitre B., et al. Inflammatory cells as well as epithelial cells in nasal polyps express vascular endothelial growth factor. Eur Respir J 2000; 15:367-372.
9. McDonald DM. Angiogenesis and remodeling of airway vasculature in chronic inflammation. Am J Respir Crit Care Med 2001; 164:S39-S45.
10. Lee OH, Xu J., Fueyo J., et al. Angiopoietin-2 decreases vascular endothelial growth factor expression by modulating HIF-1α levels in gliomas. Oncogene 2007; 27: 1310-1314.
11. Suri C., McClain J., Thurston G., et al. Increased vascularization in mice overexpressing angiopoietin-1. Science 1998; 282:468-471.
12. Yancopoulos GD, Davis S., Gale NW, et al. Vascular-specific growth factors and blood vessel formation. Nature 2000; 407:242-248.
13. Ferrara N., Carver-Moore K., Chen H., et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996; 380:439-442.
14. Daly C., Pasnikowski E., Burova E., et al. Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells. Proc Natl Acad Sci USA 2006; 103: 15491-15496.
15. Lobov IB, Brooks PC, Lang RA. Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci USA 2002; 99:11205-11210.
16. Smooak KA, Cidlowski JA. Mechanism of glucocorticoid receptor signaling during inflammation. Mech Ageing Dev 2004; 125:697-706.
17. Uchida J., Kanai K., Asano K., et al. Influence of fluticasone propionate on the production of vascular endothelial growth factor and basic fibroblast growth factor from nasal fibroblasts in vitro. In Vivo 2004; 18:767-770.
18. Matsune S., Sun D., Ohori J., et al. Inhibition of vascular endothelial growth factor by macrolides in cultured fibroblasts from nasal polyp. Laryngoscope 2005; 115: 1953-1956.