Functional aberration of myofibrils by cardiomyopathy-causing mutations in the coiled-coil region of the troponin-core domain

Biochemical and Biophysical Research Communications

Volumn 382, Issue 1, 2009, Pages 205-209

  Matsumoto, Fumiko ^a   Maeda, Kayo ^b   Chatake, Toshiyuki ^c   Maéda, Yuichiro ^b,d   Fujiwara, Satoru ^a  

^a JAPAN ATOMIC ENERGY AGENCY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

ATPase activity; Cardiomyopathy; Hydrogen bond; Molecular dynamics; Muscle regulation; Troponin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); TROPONIN;

ARTICLE; CALCIUM SIGNALING; CARDIOMYOPATHY; E244D GENE; ENZYME ACTIVITY; GENE; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; HYDROGEN BOND; K247R GENE; MOLECULAR DYNAMICS; MUSCLE FIBRIL; PRIORITY JOURNAL; PROTEIN DOMAIN; SIMULATION;

ADENOSINE TRIPHOSPHATASES; CALCIUM; CARDIOMYOPATHIES; HUMANS; HYDROGEN BONDING; MUTATION; MYOFIBRILS; PROTEIN STRUCTURE, TERTIARY; TROPONIN T;

EID: 63149094538     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.03.009     Document Type: Article

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