Familial Hypertrophic Cardiomyopathy Mutations from Different Functional Regions of Troponin T Result in Different Effects on the pH and Ca2+ Sensitivity of Cardiac Muscle Contraction

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 14488-14495

  Harada, Keita ^a   Potter, James D ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCLE; NATURAL FIBERS; PH EFFECTS; PROTEINS;

HYPERTROPHIC CARDIOMYOPATHY (FHC); MUSCLE CONTRACTION; PATHOGENESIS;

BIOCHEMISTRY;

CONTRACTILE PROTEIN; TROPONIN T;

ARTICLE; CALCIUM TRANSPORT; CELL FUNCTION; CIRCULAR DICHROISM; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; GENE LOCATION; GENE MUTATION; HEART CONTRACTION; HUMAN; HUMAN CELL; MUSCLE CONTRACTION; MUSCLE ISOMETRIC CONTRACTION; PH; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SKINNED MUSCLE FIBER; THIN FILAMENT;

CALCIUM; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; CIRCULAR DICHROISM; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROGEN-ION CONCENTRATION; MUSCLE CONTRACTION; MUTATION; MYOCARDIUM; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; TROPONIN T; ULTRAVIOLET RAYS;

SUIDAE;

EID: 2442417687     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309355200     Document Type: Article

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