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Volumn 4, Issue 4, 2008, Pages 109-115

Eurycomanone induces apoptosis through the up-regulation of p53 in human cervical carcinoma cells

Author keywords

Apoptosis; Bax; Eurycomanone; p53

Indexed keywords

CYTOTOXIC AGENT; EURYCOMANONE; METHYLENE BLUE; PROTEIN BAX; PROTEIN P53; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 63049114534     PISSN: 18160735     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (60)
  • 3
    • 0037114361 scopus 로고    scopus 로고
    • The role of human papillomavirus oncoproteins E6 and E7 in apoptosis
    • Finzer P, Aguilar-Lemarroy A, Rosl F. The role of human papillomavirus oncoproteins E6 and E7 in apoptosis. Cancer Lett 188: 15-24, 2002.
    • (2002) Cancer Lett , vol.188 , pp. 15-24
    • Finzer, P.1    Aguilar-Lemarroy, A.2    Rosl, F.3
  • 4
    • 15944403897 scopus 로고    scopus 로고
    • Adenoviral p53 effects and cell-specific E7 protein-protein interactions of human cervical cancer cells
    • Choi JW, Ahn WS, Bae SM, Lee DB, Kim YW. Adenoviral p53 effects and cell-specific E7 protein-protein interactions of human cervical cancer cells. Biosen Bioelectron 20: 2236-2243, 2005.
    • (2005) Biosen Bioelectron , vol.20 , pp. 2236-2243
    • Choi, J.W.1    Ahn, W.S.2    Bae, S.M.3    Lee, D.B.4    Kim, Y.W.5
  • 5
    • 1842484279 scopus 로고    scopus 로고
    • Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma
    • Horner SM, DeFilippis RA, Manuelidis L, DiMalo D. Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma. J Virol 78: 4063-4073, 2004.
    • (2004) J Virol , vol.78 , pp. 4063-4073
    • Horner, S.M.1    DeFilippis, R.A.2    Manuelidis, L.3    DiMalo, D.4
  • 6
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2: 342-350, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 342-350
    • zur Hausen, H.1
  • 7
    • 0035956215 scopus 로고    scopus 로고
    • The human papillomavirus E6 protein and its contribution to malignant progression
    • Mantovani F, Banks L. The human papillomavirus E6 protein and its contribution to malignant progression. Oncogene 20: 7874-7887, 2001.
    • (2001) Oncogene , vol.20 , pp. 7874-7887
    • Mantovani, F.1    Banks, L.2
  • 9
    • 0037115548 scopus 로고    scopus 로고
    • Chemoradiation of cervical cancer cells: Targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand
    • Koivusalo R, Krausz E, Ruotsalainen P, Helenius H, Hietanen S. Chemoradiation of cervical cancer cells: targeting human papillomavirus E6 and p53 leads to either augmented or attenuated apoptosis depending on the platinum carrier ligand. Cancer Res 62: 7364-7371, 2002.
    • (2002) Cancer Res , vol.62 , pp. 7364-7371
    • Koivusalo, R.1    Krausz, E.2    Ruotsalainen, P.3    Helenius, H.4    Hietanen, S.5
  • 10
    • 9644302485 scopus 로고    scopus 로고
    • Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells
    • Yim EK, Lee KH, Bae JS, Namkoong SE, Um SJ, Park JS. Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells. DNA Cell Biol 23: 769-776, 2004.
    • (2004) DNA Cell Biol , vol.23 , pp. 769-776
    • Yim, E.K.1    Lee, K.H.2    Bae, J.S.3    Namkoong, S.E.4    Um, S.J.5    Park, J.S.6
  • 11
    • 0347761416 scopus 로고    scopus 로고
    • Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia
    • Kuo PC, Damu AG, Lee KH, Wu TS. Cytotoxic and antimalarial constituents from the roots of Eurycoma longifolia. Bioorganic Med Chem 12: 537-544, 2004.
    • (2004) Bioorganic Med Chem , vol.12 , pp. 537-544
    • Kuo, P.C.1    Damu, A.G.2    Lee, K.H.3    Wu, T.S.4
  • 13
    • 0001693863 scopus 로고
    • Eurycomanone and Eurycomanol, quassinoids from the roots of Eurycoma longifolia
    • Darise M, Kohda H, Mizutani K, Tanaka O. Eurycomanone and Eurycomanol, quassinoids from the roots of Eurycoma longifolia. Phytochemistry 21: 2091-2093, 1982.
    • (1982) Phytochemistry , vol.21 , pp. 2091-2093
    • Darise, M.1    Kohda, H.2    Mizutani, K.3    Tanaka, O.4
  • 17
    • 0027140526 scopus 로고
    • C18 and C19 quassinoids from Eurycoma longifolia
    • Itokawa H, Qin XR, Morita H, Takeya K. C18 and C19 quassinoids from Eurycoma longifolia. J Nat Prod 56: 1766-1771, 1993.
    • (1993) J Nat Prod , vol.56 , pp. 1766-1771
    • Itokawa, H.1    Qin, X.R.2    Morita, H.3    Takeya, K.4
  • 18
    • 0026693054 scopus 로고
    • Cytotoxic quassinoids tirucallane-type triterpenes from the woods of Eurycoma longifolia
    • Itokawa H, Kishi E, Morita H, Takeya K. Cytotoxic quassinoids tirucallane-type triterpenes from the woods of Eurycoma longifolia. Chem Pharm Bull 40: 1035-1055, 1992.
    • (1992) Chem Pharm Bull , vol.40 , pp. 1035-1055
    • Itokawa, H.1    Kishi, E.2    Morita, H.3    Takeya, K.4
  • 21
    • 0034718387 scopus 로고    scopus 로고
    • Eurycolactone A-C, novel quasinoids from Eurycoma longifolia
    • Ang HH, Hitotsuyanagi Y, Takeya K. Eurycolactone A-C, novel quasinoids from Eurycoma longifolia. Tetrahedron Lett 41: 6849-6853, 2000.
    • (2000) Tetrahedron Lett , vol.41 , pp. 6849-6853
    • Ang, H.H.1    Hitotsuyanagi, Y.2    Takeya, K.3
  • 25
    • 0000777466 scopus 로고
    • Biphenylneolignans from wood of Eurycoma longifolia
    • Morita H, Kishi E, Takeya K, Itokawa H. Biphenylneolignans from wood of Eurycoma longifolia. Phytochemistry 31: 3993-3995, 1992.
    • (1992) Phytochemistry , vol.31 , pp. 3993-3995
    • Morita, H.1    Kishi, E.2    Takeya, K.3    Itokawa, H.4
  • 26
    • 21344444795 scopus 로고    scopus 로고
    • Induction of apoptosis by Eurycoma longifolia Jack extract
    • Tee TT, Azimahtol HLP. Induction of apoptosis by Eurycoma longifolia Jack extract, Anticancer Res 25: 2205-2214, 2005.
    • (2005) Anticancer Res , vol.25 , pp. 2205-2214
    • Tee, T.T.1    Azimahtol, H.L.P.2
  • 27
    • 63049126017 scopus 로고    scopus 로고
    • Eurycomanone exert antiproliferative activity via apoptosis upon MCF-7 cells
    • ke-7
    • Cheah SC, Azimahtol HLP. Eurycomanone exert antiproliferative activity via apoptosis upon MCF-7 cells. Proc Sym Biol Kebangsaan Malaysia ke-7: 73-77, 2004.
    • (2004) Proc Sym Biol Kebangsaan Malaysia , pp. 73-77
    • Cheah, S.C.1    Azimahtol, H.L.P.2
  • 29
    • 0042816288 scopus 로고    scopus 로고
    • Styrylpirone derivatives induce apoptosis through the up-regulation of Bax in human breast cancer cell lines MCF-7
    • Lee ATC, Azimahtol HLP. Styrylpirone derivatives induce apoptosis through the up-regulation of Bax in human breast cancer cell lines MCF-7. J Biochem Mol Biol 36: 269-274, 2003.
    • (2003) J Biochem Mol Biol , vol.36 , pp. 269-274
    • Lee, A.T.C.1    Azimahtol, H.L.P.2
  • 30
    • 0033601275 scopus 로고    scopus 로고
    • Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7
    • Hishikawa K, Oemar BS, Tanner FC, Nakaki T, Luscher TF, Fujii T. Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7. J Biol Chem 274: 37461-37466, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 37461-37466
    • Hishikawa, K.1    Oemar, B.S.2    Tanner, F.C.3    Nakaki, T.4    Luscher, T.F.5    Fujii, T.6
  • 31
    • 3142740358 scopus 로고    scopus 로고
    • Apoptosis: A four week laboratory investigation for advanced molecular and cellular biology students
    • Dibartolomeis SM, Moné JP. Apoptosis: a four week laboratory investigation for advanced molecular and cellular biology students. Cell Biol Edu 7242F: 275-295, 2003.
    • (2003) Cell Biol Edu , vol.7242 F , pp. 275-295
    • Dibartolomeis, S.M.1    Moné, J.P.2
  • 32
    • 33745007205 scopus 로고    scopus 로고
    • Laboratory exercise: A laboratory exercise in comparative DNA analysis
    • Brown LR. Laboratory exercise: A laboratory exercise in comparative DNA analysis. Biochem Mol Biol Edu 31: 177-179, 2003.
    • (2003) Biochem Mol Biol Edu , vol.31 , pp. 177-179
    • Brown, L.R.1
  • 33
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 407: 784-788, 2000.
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 34
    • 0042318707 scopus 로고    scopus 로고
    • Apoptosis-an introduction
    • Lawen A. Apoptosis-an introduction. BioEssay 25: 888-896, 2003.
    • (2003) BioEssay , vol.25 , pp. 888-896
    • Lawen, A.1
  • 35
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 36
    • 0037075898 scopus 로고    scopus 로고
    • Activation of the p53 tumor suppressor protein
    • Vousden KH. Activation of the p53 tumor suppressor protein. Biochim Biophys Acta 1602: 47-59, 2002.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 47-59
    • Vousden, K.H.1
  • 37
    • 0031012054 scopus 로고    scopus 로고
    • Plant-derived anticancer agents
    • Pezzuto JM. Plant-derived anticancer agents. Biochem Pharmacol 53: 121-133, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 121-133
    • Pezzuto, J.M.1
  • 39
    • 0030999750 scopus 로고    scopus 로고
    • Apoptosis and the dilemma of cancer chemotherapy
    • Hannun YA. Apoptosis and the dilemma of cancer chemotherapy. Blood 89: 1845-1853, 1997.
    • (1997) Blood , vol.89 , pp. 1845-1853
    • Hannun, Y.A.1
  • 40
    • 0030757751 scopus 로고    scopus 로고
    • Morphological and biochemical characterization and analysis of apoptosis
    • Allen RT, Hunter III WJ, Agrawal DK. Morphological and biochemical characterization and analysis of apoptosis. J Pharmacol Toxicol Method 37: 215-228, 1997.
    • (1997) J Pharmacol Toxicol Method , vol.37 , pp. 215-228
    • Allen, R.T.1    Hunter III, W.J.2    Agrawal, D.K.3
  • 41
    • 0031780665 scopus 로고    scopus 로고
    • Ubiquitin, E6-AP, and their role in p53 inactivation
    • Scheffner M. Ubiquitin, E6-AP, and their role in p53 inactivation. Pharmacol Ther 78: 129-139, 1998.
    • (1998) Pharmacol Ther , vol.78 , pp. 129-139
    • Scheffner, M.1
  • 42
    • 0032192140 scopus 로고    scopus 로고
    • The complexity of p53 modulation: Emerging patterns from divergent signals
    • Giaccia AJ, Kastan MB. The complexity of p53 modulation: emerging patterns from divergent signals. Gene Dev 12: 2973-2983, 1998.
    • (1998) Gene Dev , vol.12 , pp. 2973-2983
    • Giaccia, A.J.1    Kastan, M.B.2
  • 43
    • 0031015044 scopus 로고    scopus 로고
    • Ubiquitination of p53 and p21 is differentially affected by ionizing radiation and UV radiation
    • Maki CG, Howley PM. Ubiquitination of p53 and p21 is differentially affected by ionizing radiation and UV radiation. Mol Cell Biol 17: 355-363, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 355-363
    • Maki, C.G.1    Howley, P.M.2
  • 44
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • Lakin ND, Jackson SP. Regulation of p53 in response to DNA damage. Oncogene 18: 7644-7655, 1999.
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 45
    • 21344447259 scopus 로고    scopus 로고
    • Xanthorrhizol induces apoptosis via the up-regulation of Bax and p53 in HeLa cells
    • Ismail N, Azimahtol HLP, Nallapan M. Xanthorrhizol induces apoptosis via the up-regulation of Bax and p53 in HeLa cells. Anticancer Res 25: 2221-2228, 2005.
    • (2005) Anticancer Res , vol.25 , pp. 2221-2228
    • Ismail, N.1    Azimahtol, H.L.P.2    Nallapan, M.3
  • 46
    • 0038780664 scopus 로고    scopus 로고
    • Human papilloma virus type 16+ and 18+ cervical carcinoma cells are sensitive to staurosporine-mediated apoptosis
    • Bernard B, Pretet JL, Charlot JF, Mougin C. Human papilloma virus type 16+ and 18+ cervical carcinoma cells are sensitive to staurosporine-mediated apoptosis. Biol Cell 95: 17-26, 2003.
    • (2003) Biol Cell , vol.95 , pp. 17-26
    • Bernard, B.1    Pretet, J.L.2    Charlot, J.F.3    Mougin, C.4
  • 47
    • 12744276051 scopus 로고    scopus 로고
    • Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells
    • Zheng PW, Chiang LC, Lin CC. Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells. Life Sci 76: 1367-1379, 2005.
    • (2005) Life Sci , vol.76 , pp. 1367-1379
    • Zheng, P.W.1    Chiang, L.C.2    Lin, C.C.3
  • 48
    • 0034806033 scopus 로고    scopus 로고
    • Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing p53
    • Reddy VG, Khanna N, Singh N. Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing p53. Biochem Biophys Res Commun 282: 409-415, 2001.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 409-415
    • Reddy, V.G.1    Khanna, N.2    Singh, N.3
  • 49
    • 33846277976 scopus 로고    scopus 로고
    • p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: A novel target of p53 in apoptosis
    • Singh S, Upadhyay AU, Ajay AK, Bhat MK. p53 regulates ERK activation in carboplatin induced apoptosis in cervical carcinoma: A novel target of p53 in apoptosis. FEBS Lett 581: 289-295, 2007.
    • (2007) FEBS Lett , vol.581 , pp. 289-295
    • Singh, S.1    Upadhyay, A.U.2    Ajay, A.K.3    Bhat, M.K.4
  • 50
    • 0343811694 scopus 로고    scopus 로고
    • Modulation of NF-?B, p53 and Bcl-2 in apoptosis induced by cisplatin in HeLa cells
    • Maldonado V, Melendez-Zajgla J, Ortega A. Modulation of NF-?B, p53 and Bcl-2 in apoptosis induced by cisplatin in HeLa cells. Mutation Res 381: 67-75, 1997.
    • (1997) Mutation Res , vol.381 , pp. 67-75
    • Maldonado, V.1    Melendez-Zajgla, J.2    Ortega, A.3
  • 53
    • 0034006177 scopus 로고    scopus 로고
    • Effect of p53 status on sensitivity to platinum complexes in human ovarian cancer cell line
    • Pestell KE, Hobbs SM, Titley JC, Kelland LR, Walton ML. Effect of p53 status on sensitivity to platinum complexes in human ovarian cancer cell line. Mol Pharmacol 57: 503-511, 2000.
    • (2000) Mol Pharmacol , vol.57 , pp. 503-511
    • Pestell, K.E.1    Hobbs, S.M.2    Titley, J.C.3    Kelland, L.R.4    Walton, M.L.5
  • 54
    • 0033028043 scopus 로고    scopus 로고
    • The role of p53 in tumour suppression: Lessons from mouse models
    • Attardi LD, Jacks T. The role of p53 in tumour suppression: lessons from mouse models. Cell Mol Life Sci 55: 48-63, 1999.
    • (1999) Cell Mol Life Sci , vol.55 , pp. 48-63
    • Attardi, L.D.1    Jacks, T.2
  • 55
    • 0033230581 scopus 로고    scopus 로고
    • The cellular response to p53: The decision between life and death
    • Sionov RV, Haupt Y. The cellular response to p53: the decision between life and death, Oncogene 18: 6145-6157, 1999.
    • (1999) Oncogene , vol.18 , pp. 6145-6157
    • Sionov, R.V.1    Haupt, Y.2
  • 57
    • 0035970025 scopus 로고    scopus 로고
    • Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
    • Hengstermann A, Linares LK, Ciechanover A, Whitaker NJ, Scheffner M. Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells. Proc Natl Acad Sci USA 98: 1218-1223, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1218-1223
    • Hengstermann, A.1    Linares, L.K.2    Ciechanover, A.3    Whitaker, N.J.4    Scheffner, M.5
  • 59
    • 4444261662 scopus 로고    scopus 로고
    • Prognostic significance of Bax, Bcl-2, and p53 expressions in cervical squamous cell carcinoma treated by radiotherapy
    • Wootipoom V, Lekhyananda N, Phungrassami T, Boonyaphiphat P, Thongsuksai, P. Prognostic significance of Bax, Bcl-2, and p53 expressions in cervical squamous cell carcinoma treated by radiotherapy. Gyn Oncol 94: 636-642, 2004.
    • (2004) Gyn Oncol , vol.94 , pp. 636-642
    • Wootipoom, V.1    Lekhyananda, N.2    Phungrassami, T.3    Boonyaphiphat, P.4    Thongsuksai, P.5
  • 60
    • 0032781685 scopus 로고    scopus 로고
    • Decreased programmed cell death in the uterine cervix associated with high risk human papilloma virus infection
    • Nair P, Nair MK, Jayaprakash PG, Pillai MR. Decreased programmed cell death in the uterine cervix associated with high risk human papilloma virus infection. Path Oncol Res 5: 95-103, 1999.
    • (1999) Path Oncol Res , vol.5 , pp. 95-103
    • Nair, P.1    Nair, M.K.2    Jayaprakash, P.G.3    Pillai, M.R.4


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