메뉴 건너뛰기




Volumn 136, Issue 4, 2009, Pages 1157-1160

PPARG: A New Independent Marker for Colorectal Cancer Survival

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; ROSIGLITAZONE; TROGLITAZONE; TUMOR MARKER;

EID: 62949228303     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.02.022     Document Type: Editorial
Times cited : (9)

References (32)
  • 2
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
    • Calle E.E., and Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 4 (2004) 579-591
    • (2004) Nat Rev Cancer , vol.4 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 3
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle E.E., Rodriguez C., Walker-Thurmond K., et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348 (2003) 1625-1638
    • (2003) N Engl J Med , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3
  • 4
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman B.M., Chen J., and Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A 94 (1997) 4312-4317
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 5
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
    • Kliewer S.A., Sundseth S.S., Jones S.A., et al. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proc Natl Acad Sci U S A 94 (1997) 4318-4323
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1    Sundseth, S.S.2    Jones, S.A.3
  • 6
    • 62949100452 scopus 로고    scopus 로고
    • Colorectal cancer expression of PPARG (peroxisome proliferator-activated receptor-gamma) is associated with good prognosis
    • Ogino S., Shima K., Baba Y., et al. Colorectal cancer expression of PPARG (peroxisome proliferator-activated receptor-gamma) is associated with good prognosis. Gastroenterology 136 (2009) 1242-1250
    • (2009) Gastroenterology , vol.136 , pp. 1242-1250
    • Ogino, S.1    Shima, K.2    Baba, Y.3
  • 7
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: the diverse biology of PPARgamma
    • Tontonoz P., and Spiegelman B.M. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem 77 (2008) 289-312
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 8
    • 36049034344 scopus 로고    scopus 로고
    • Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms
    • Straus D.S., and Glass C.K. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol 28 (2007) 551-558
    • (2007) Trends Immunol , vol.28 , pp. 551-558
    • Straus, D.S.1    Glass, C.K.2
  • 9
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and cancers: complex stories
    • Michalik L., Desvergne B., and Wahli W. Peroxisome-proliferator-activated receptors and cancers: complex stories. Nat Rev Cancer 4 (2004) 61-70
    • (2004) Nat Rev Cancer , vol.4 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 10
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P., Hu E., and Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 79 (1994) 1147-1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 11
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann J.M., Moore L.B., Smith-Oliver T.A., et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270 (1995) 12953-12956
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3
  • 12
    • 0031844535 scopus 로고    scopus 로고
    • The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers
    • DuBois R.N., Gupta R., Brockman J., et al. The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers. Carcinogenesis 19 (1998) 49-53
    • (1998) Carcinogenesis , vol.19 , pp. 49-53
    • DuBois, R.N.1    Gupta, R.2    Brockman, J.3
  • 13
    • 0031671246 scopus 로고    scopus 로고
    • Differentiation and reversal of malignant changes in colon cancer through PPARgamma
    • Sarraf P., Mueller E., Jones D., et al. Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nat Med 4 (1998) 1046-1052
    • (1998) Nat Med , vol.4 , pp. 1046-1052
    • Sarraf, P.1    Mueller, E.2    Jones, D.3
  • 14
    • 0031595670 scopus 로고    scopus 로고
    • Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells
    • Brockman J.A., Gupta R.A., and Dubois R.N. Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 115 (1998) 1049-1055
    • (1998) Gastroenterology , vol.115 , pp. 1049-1055
    • Brockman, J.A.1    Gupta, R.A.2    Dubois, R.N.3
  • 15
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
    • Lefebvre A.M., Chen I., Desreumaux P., et al. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. Nat Med 4 (1998) 1053-1057
    • (1998) Nat Med , vol.4 , pp. 1053-1057
    • Lefebvre, A.M.1    Chen, I.2    Desreumaux, P.3
  • 16
    • 0031667938 scopus 로고    scopus 로고
    • Activators of the nuclear receptor PPARgamma enhance colon polyp formation
    • Saez E., Tontonoz P., Nelson M.C., et al. Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nat Med 4 (1998) 1058-1061
    • (1998) Nat Med , vol.4 , pp. 1058-1061
    • Saez, E.1    Tontonoz, P.2    Nelson, M.C.3
  • 17
    • 0037109043 scopus 로고    scopus 로고
    • APC-dependent suppression of colon carcinogenesis by PPARgamma
    • Girnun G.D., Smith W.M., Drori S., et al. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proc Natl Acad Sci U S A 99 (2002) 13771-13776
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13771-13776
    • Girnun, G.D.1    Smith, W.M.2    Drori, S.3
  • 18
    • 0036730017 scopus 로고    scopus 로고
    • A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer
    • Kulke M.H., Demetri G.D., Sharpless N.E., et al. A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J 8 (2002) 395-399
    • (2002) Cancer J , vol.8 , pp. 395-399
    • Kulke, M.H.1    Demetri, G.D.2    Sharpless, N.E.3
  • 19
    • 34248192254 scopus 로고    scopus 로고
    • Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes
    • Govindarajan R., Ratnasinghe L., Simmons D.L., et al. Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes. J Clin Oncol 25 (2007) 1476-1481
    • (2007) J Clin Oncol , vol.25 , pp. 1476-1481
    • Govindarajan, R.1    Ratnasinghe, L.2    Simmons, D.L.3
  • 20
    • 57249086247 scopus 로고    scopus 로고
    • Thiazolidinedione therapy is not associated with increased colonic neoplasia risk in patients with diabetes mellitus
    • Lewis J.D., Capra A.M., Achacoso N.S., et al. Thiazolidinedione therapy is not associated with increased colonic neoplasia risk in patients with diabetes mellitus. Gastroenterology 135 (2008) 1914-1923
    • (2008) Gastroenterology , vol.135 , pp. 1914-1923
    • Lewis, J.D.1    Capra, A.M.2    Achacoso, N.S.3
  • 21
    • 34250330771 scopus 로고    scopus 로고
    • EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality
    • Gustafsson A., Hansson E., Kressner U., et al. EP1-4 subtype, COX and PPAR gamma receptor expression in colorectal cancer in prediction of disease-specific mortality. Int J Cancer 121 (2007) 232-240
    • (2007) Int J Cancer , vol.121 , pp. 232-240
    • Gustafsson, A.1    Hansson, E.2    Kressner, U.3
  • 22
    • 34547843591 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor-gamma in colon cancer: correlation with histopathological parameters, cell cycle-related molecules, and patients' survival
    • Theocharis S., Giaginis C., Parasi A., et al. Expression of peroxisome proliferator-activated receptor-gamma in colon cancer: correlation with histopathological parameters, cell cycle-related molecules, and patients' survival. Dig Dis Sci 52 (2007) 2305-2311
    • (2007) Dig Dis Sci , vol.52 , pp. 2305-2311
    • Theocharis, S.1    Giaginis, C.2    Parasi, A.3
  • 23
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady W.M., and Carethers J.M. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 135 (2008) 1079-1099
    • (2008) Gastroenterology , vol.135 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 24
    • 33646160623 scopus 로고    scopus 로고
    • Inflammation, a key event in cancer development
    • Lu H., Ouyang W., and Huang C. Inflammation, a key event in cancer development. Mol Cancer Res 4 (2006) 221-233
    • (2006) Mol Cancer Res , vol.4 , pp. 221-233
    • Lu, H.1    Ouyang, W.2    Huang, C.3
  • 26
    • 34848833193 scopus 로고    scopus 로고
    • Nuclear hormone receptors and intestinal inflammation
    • Wu G.D. Nuclear hormone receptors and intestinal inflammation. Gastroenterology 133 (2007) 1068
    • (2007) Gastroenterology , vol.133 , pp. 1068
    • Wu, G.D.1
  • 27
    • 34547627893 scopus 로고    scopus 로고
    • PPARgamma in immunity and inflammation: cell types and diseases
    • Szeles L., Torocsik D., and Nagy L. PPARgamma in immunity and inflammation: cell types and diseases. Biochim Biophys Acta 1771 (2007) 1014-1030
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 1014-1030
    • Szeles, L.1    Torocsik, D.2    Nagy, L.3
  • 28
    • 40849140987 scopus 로고    scopus 로고
    • Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB
    • Bren-Mattison Y., Meyer A.M., Van Putten V., et al. Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB. Mol Pharmacol 73 (2008) 709-717
    • (2008) Mol Pharmacol , vol.73 , pp. 709-717
    • Bren-Mattison, Y.1    Meyer, A.M.2    Van Putten, V.3
  • 29
    • 34247626779 scopus 로고    scopus 로고
    • Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor gamma
    • Zhang Y.Q., Tang X.Q., Sun L., et al. Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor gamma. World J Gastroenterol 13 (2007) 1534-1540
    • (2007) World J Gastroenterol , vol.13 , pp. 1534-1540
    • Zhang, Y.Q.1    Tang, X.Q.2    Sun, L.3
  • 30
    • 44449155990 scopus 로고    scopus 로고
    • Chemotherapeutic drugs induce PPAR-gamma expression and show sequence-specific synergy with PPAR-gamma ligands in inhibition of non-small cell lung cancer
    • Reddy R.C., Srirangam A., Reddy K., et al. Chemotherapeutic drugs induce PPAR-gamma expression and show sequence-specific synergy with PPAR-gamma ligands in inhibition of non-small cell lung cancer. Neoplasia 10 (2008) 597-603
    • (2008) Neoplasia , vol.10 , pp. 597-603
    • Reddy, R.C.1    Srirangam, A.2    Reddy, K.3
  • 31
    • 34247558604 scopus 로고    scopus 로고
    • Synergy between PPARgamma ligands and platinum-based drugs in cancer
    • Girnun G.D., Naseri E., Vafai S.B., et al. Synergy between PPARgamma ligands and platinum-based drugs in cancer. Cancer Cell 11 (2007) 395-406
    • (2007) Cancer Cell , vol.11 , pp. 395-406
    • Girnun, G.D.1    Naseri, E.2    Vafai, S.B.3
  • 32
    • 58149178162 scopus 로고    scopus 로고
    • Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin
    • Girnun G.D., Chen L., Silvaggi J., et al. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clin Cancer Res 14 (2008) 6478-6486
    • (2008) Clin Cancer Res , vol.14 , pp. 6478-6486
    • Girnun, G.D.1    Chen, L.2    Silvaggi, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.