Decreased protein synthesis of Hsp27 associated with cellular toxicity in a cell model of Machado-Joseph disease

Neuroscience Letters

Volumn 454, Issue 2, 2009, Pages 152-156

  Chang, Wei Hsiu ^a   Tien, Chih Liang ^a   Chen, Tzu Jung ^a   Nukina, Nobuyuki ^b   Hsieh, Mingli ^a  

^a TUNGHAI UNIVERSITY   (Taiwan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Heat shock protein 27; Machado Joseph disease; Mutant ataxin 3; Protease inhibitor; Protein synthesis

Indexed keywords

ATAXIN 3; HEAT SHOCK PROTEIN 27; METHIONINE; PROTEASOME; SULFUR 35;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MACHADO JOSEPH DISEASE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; CYSTEINE PROTEINASE INHIBITORS; GENE EXPRESSION; HSP27 HEAT-SHOCK PROTEINS; HUMANS; LEUPEPTINS; MACHADO-JOSEPH DISEASE; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PEPTIDES; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; TRANSFECTION;

EID: 62949154852     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.03.004     Document Type: Article

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