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Volumn 116, Issue 1, 2009, Pages 13-22

Aging and α-synuclein affect synaptic plasticity in the dentate gyrus

Author keywords

Synuclein; Dentate gyrus; Paired pulse facilitation; Perforant pathway; Transgenic

Indexed keywords

ALPHA SYNUCLEIN;

EID: 62949117379     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-008-0149-x     Document Type: Article
Times cited : (42)

References (45)
  • 1
    • 0024450321 scopus 로고
    • Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats
    • TE Albertson RM Joy 1989 Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats Exp Neurol 106 142 149
    • (1989) Exp Neurol , vol.106 , pp. 142-149
    • Albertson, T.E.1    Joy, R.M.2
  • 2
    • 0035826523 scopus 로고    scopus 로고
    • The time course of the hyperactivity that follows lesions or temporary inactivation of the fimbria-fornix
    • DM Bannerman G Gilmour G Norman 2001 The time course of the hyperactivity that follows lesions or temporary inactivation of the fimbria-fornix Behav Brain Res 120 1 11
    • (2001) Behav Brain Res , vol.120 , pp. 1-11
    • Bannerman, D.M.1    Gilmour, G.2    Norman, G.3
  • 3
    • 0028107456 scopus 로고
    • Normal aging: Regionally specific changes in hippocampal synaptic transmission
    • CA Barnes 1994 Normal aging: regionally specific changes in hippocampal synaptic transmission Trends Neurosci 17 13 18
    • (1994) Trends Neurosci , vol.17 , pp. 13-18
    • Barnes, C.A.1
  • 4
    • 0019225823 scopus 로고
    • Physiological compensation for loss of afferent synapses in rat hippocampal granule cells during senescence
    • CA Barnes BL McNaughton 1980 Physiological compensation for loss of afferent synapses in rat hippocampal granule cells during senescence J Physiol 309 473 485
    • (1980) J Physiol , vol.309 , pp. 473-485
    • Barnes, C.A.1    McNaughton, B.L.2
  • 5
    • 33646375711 scopus 로고    scopus 로고
    • High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
    • A Bender KJ Krishnan CM Morris 2006 High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease Nat Genet 38 515 517
    • (2006) Nat Genet , vol.38 , pp. 515-517
    • Bender, A.1    Krishnan, K.J.2    Morris, C.M.3
  • 6
    • 14344263884 scopus 로고    scopus 로고
    • The role of alpha-synuclein in neurodegenerative diseases
    • MC Bennett 2005 The role of alpha-synuclein in neurodegenerative diseases Pharmacol Ther 105 311 331
    • (2005) Pharmacol Ther , vol.105 , pp. 311-331
    • Bennett, M.C.1
  • 7
    • 21744439461 scopus 로고    scopus 로고
    • Timing in synaptic plasticity: From detection to integration
    • GQ Bi J Rubin 2005 Timing in synaptic plasticity: from detection to integration Trends Neurosci 28 222 228
    • (2005) Trends Neurosci , vol.28 , pp. 222-228
    • Bi, G.Q.1    Rubin, J.2
  • 8
    • 0015799240 scopus 로고
    • Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path
    • TVP Bliss T Lomo 1973 Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path J Physiol 232 331 356
    • (1973) J Physiol , vol.232 , pp. 331-356
    • Bliss, T.V.P.1    Lomo, T.2
  • 10
    • 29244439038 scopus 로고    scopus 로고
    • Neural plasticity in the ageing brain
    • SN Burke CA Barnes 2006 Neural plasticity in the ageing brain Nat Rev Neurosci 7 30 40
    • (2006) Nat Rev Neurosci , vol.7 , pp. 30-40
    • Burke, S.N.1    Barnes, C.A.2
  • 11
    • 33751118534 scopus 로고    scopus 로고
    • Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
    • Y Chu JH Kordower 2007 Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: is this the target for Parkinson's disease? Neurobiol Dis 25 134 149
    • (2007) Neurobiol Dis , vol.25 , pp. 134-149
    • Chu, Y.1    Kordower, J.H.2
  • 12
    • 0033215063 scopus 로고    scopus 로고
    • Synucleins in synaptic plasticity and neurodegenerative disorders
    • DF Clayton JM George 1999 Synucleins in synaptic plasticity and neurodegenerative disorders J Neurosci Res 58 120 129
    • (1999) J Neurosci Res , vol.58 , pp. 120-129
    • Clayton, D.F.1    George, J.M.2
  • 13
    • 0142063037 scopus 로고    scopus 로고
    • Alpha-synuclein: Between synaptic function and dysfunction
    • G Di Rosa D Puzzo A Sant'Angelo 2003 Alpha-synuclein: between synaptic function and dysfunction Histol Histopathol 18 1257 1266
    • (2003) Histol Histopathol , vol.18 , pp. 1257-1266
    • Di Rosa, G.1    Puzzo, D.2    Sant'Angelo, A.3
  • 14
    • 0028846935 scopus 로고
    • Stimulation at 1-5 Hz does not produce long-term depression or depotentiation in the hippocampus of the adult rat in vivo
    • ML Errington TVP Bliss G Richter-Levin 1995 Stimulation at 1-5 Hz does not produce long-term depression or depotentiation in the hippocampus of the adult rat in vivo J Neurophysiol 74 1793 1799
    • (1995) J Neurophysiol , vol.74 , pp. 1793-1799
    • Errington, M.L.1    Bliss, T.V.P.2    Richter-Levin, G.3
  • 15
    • 0025086433 scopus 로고
    • MPTP-induced hypoactivity in mice: Reversal by L-dopa
    • A Fredriksson A Plaznik E Sundström 1990 MPTP-induced hypoactivity in mice: reversal by L-dopa Pharm Toxicol 67 295 301
    • (1990) Pharm Toxicol , vol.67 , pp. 295-301
    • Fredriksson, A.1    Plaznik, A.2    Sundström, E.3
  • 16
    • 34447570901 scopus 로고    scopus 로고
    • Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice
    • C Freichel M Neumann T Ballard 2007 Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice Neurobiol Aging 28 1421 1435
    • (2007) Neurobiol Aging , vol.28 , pp. 1421-1435
    • Freichel, C.1    Neumann, M.2    Ballard, T.3
  • 17
    • 0030337503 scopus 로고    scopus 로고
    • Interneurons of the hippocampus
    • TF Freund G Buzsaki 1996 Interneurons of the hippocampus Hippocampus 6 347 470
    • (1996) Hippocampus , vol.6 , pp. 347-470
    • Freund, T.F.1    Buzsaki, G.2
  • 18
    • 0037487259 scopus 로고    scopus 로고
    • Reduced synaptic plasticity in the lateral perforant path input to the dentate gyrus of aged C57BL/6 mice
    • DJ Froc B Eadie AM Li 2003 Reduced synaptic plasticity in the lateral perforant path input to the dentate gyrus of aged C57BL/6 mice J Neurophysiol 90 32 38
    • (2003) J Neurophysiol , vol.90 , pp. 32-38
    • Froc, D.J.1    Eadie, B.2    Li, A.M.3
  • 19
    • 0035109738 scopus 로고    scopus 로고
    • Synucleinopathies: Clinical and pathological implications
    • JE Galvin VM Lee JQ Trojanowski 2001 Synucleinopathies: clinical and pathological implications Arch Neurol 58 186 190
    • (2001) Arch Neurol , vol.58 , pp. 186-190
    • Galvin, J.E.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 20
    • 35248841938 scopus 로고    scopus 로고
    • Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: Potential relation with the loss of somatostatin GABAergic neurons
    • MP Gavilan E Revilla C Pintado 2007 Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons J Neurochem 103 984 996
    • (2007) J Neurochem , vol.103 , pp. 984-996
    • Gavilan, M.P.1    Revilla, E.2    Pintado, C.3
  • 21
    • 0030565550 scopus 로고    scopus 로고
    • Enhancement of paired-pulse depression in the dentate gyrus in vivo by the NMDA antagonist, MK-801, and electrical kindling
    • ME Gilbert LJ Burdette 1996 Enhancement of paired-pulse depression in the dentate gyrus in vivo by the NMDA antagonist, MK-801, and electrical kindling Brain Res 732 201 208
    • (1996) Brain Res , vol.732 , pp. 201-208
    • Gilbert, M.E.1    Burdette, L.J.2
  • 22
    • 0037333642 scopus 로고    scopus 로고
    • Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice
    • T Gomez-Isla MC Irizarry A Mariash 2003 Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice Neurobiol Aging 24 245 258
    • (2003) Neurobiol Aging , vol.24 , pp. 245-258
    • Gomez-Isla, T.1    Irizarry, M.C.2    Mariash, A.3
  • 23
    • 34548726221 scopus 로고    scopus 로고
    • Role of alpha-synuclein in synaptic glutamate release
    • I Gureviciene K Gurevicius H Tanila 2007 Role of alpha-synuclein in synaptic glutamate release Neurobiol Dis 28 83 89
    • (2007) Neurobiol Dis , vol.28 , pp. 83-89
    • Gureviciene, I.1    Gurevicius, K.2    Tanila, H.3
  • 24
    • 0037741922 scopus 로고    scopus 로고
    • Hypothermia in mice tested in Morris water maze
    • H Iivonen L Nurminen M Harri 2003 Hypothermia in mice tested in Morris water maze Behav Brain Res 141 207 213
    • (2003) Behav Brain Res , vol.141 , pp. 207-213
    • Iivonen, H.1    Nurminen, L.2    Harri, M.3
  • 25
    • 0032545154 scopus 로고    scopus 로고
    • Degenerative terminals of the perforant pathway are human alpha-synuclein-immunoreactive in the hippocampus of patients with diffuse Lewy body disease
    • E Iseki W Marui K Kosaka 1998 Degenerative terminals of the perforant pathway are human alpha-synuclein-immunoreactive in the hippocampus of patients with diffuse Lewy body disease Neurosci Lett 258 81 84
    • (1998) Neurosci Lett , vol.258 , pp. 81-84
    • Iseki, E.1    Marui, W.2    Kosaka, K.3
  • 26
    • 10944242594 scopus 로고    scopus 로고
    • Intracellular alpha-synuclein (alpha-syn) accumulation in transgenic mice expressing A30P alpha-syn mutation
    • P Jakala J Puolivali P Kerokoski 2002 Intracellular alpha-synuclein (alpha-syn) accumulation in transgenic mice expressing A30P alpha-syn mutation Neurobiol Aging 23 S252
    • (2002) Neurobiol Aging , vol.23 , pp. 252
    • Jakala, P.1    Puolivali, J.2    Kerokoski, P.3
  • 27
    • 0034280435 scopus 로고    scopus 로고
    • Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain
    • PJ Kahle M Neumann L Ozmen 2000 Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain J Neurosci 20 6365 6373
    • (2000) J Neurosci , vol.20 , pp. 6365-6373
    • Kahle, P.J.1    Neumann, M.2    Ozmen, L.3
  • 28
    • 0037220577 scopus 로고    scopus 로고
    • Differential effects of short- and long-term potentiation on cell firing in the CA1 region of the hippocampus
    • CP Marder DV Buonomano 2003 Differential effects of short- and long-term potentiation on cell firing in the CA1 region of the hippocampus J Neurosci 23 112 121
    • (2003) J Neurosci , vol.23 , pp. 112-121
    • Marder, C.P.1    Buonomano, D.V.2
  • 29
    • 0020005069 scopus 로고
    • Long-term synaptic enhancement and short-term potentiation in rat fascia dentata act through different mechanisms
    • BL McNaughton 1982 Long-term synaptic enhancement and short-term potentiation in rat fascia dentata act through different mechanisms J Physiol 324 249 262
    • (1982) J Physiol , vol.324 , pp. 249-262
    • McNaughton, B.L.1
  • 31
    • 0026458086 scopus 로고
    • Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus
    • RM Mulkey RC Malenka 1992 Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus Neuron 9 967 975
    • (1992) Neuron , vol.9 , pp. 967-975
    • Mulkey, R.M.1    Malenka, R.C.2
  • 32
    • 12144267004 scopus 로고    scopus 로고
    • Fluorescence studies suggest a role for alpha-synuclein in the phosphatidylinositol lipid signaling pathway
    • V Narayanan Y Guo S Scarlata 2005 Fluorescence studies suggest a role for alpha-synuclein in the phosphatidylinositol lipid signaling pathway Biochemistry 44 462 470
    • (2005) Biochemistry , vol.44 , pp. 462-470
    • Narayanan, V.1    Guo, Y.2    Scarlata, S.3
  • 33
    • 2642514788 scopus 로고    scopus 로고
    • Alpha-synuclein: Normal function and role in neurodegenerative diseases
    • EH Norris BI Giasson VM Lee 2004 Alpha-synuclein: normal function and role in neurodegenerative diseases Curr Top Dev Biol 60 17 54
    • (2004) Curr Top Dev Biol , vol.60 , pp. 17-54
    • Norris, E.H.1    Giasson, B.I.2    Lee, V.M.3
  • 34
    • 0027233066 scopus 로고
    • Modulation of paired-pulse activation in the hippocampal dentate gyrus by cholecystokinin, baclofen and bicuculline
    • E Rich-Bennett D Dahl BB Lecompte 3rd 1993 Modulation of paired-pulse activation in the hippocampal dentate gyrus by cholecystokinin, baclofen and bicuculline Neuropeptides 24 263 270
    • (1993) Neuropeptides , vol.24 , pp. 263-270
    • Rich-Bennett, E.1    Dahl, D.2    Lecompte III, B.B.3
  • 35
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • ES Rosenzweig CA Barnes 2003 Impact of aging on hippocampal function: plasticity, network dynamics, and cognition Prog Neurobiol 69 143 179
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 36
    • 14944348552 scopus 로고    scopus 로고
    • The role of alpha-synuclein in both neuroprotection and neurodegeneration
    • A Sidhu C Wersinger CE Moussa 2004 The role of alpha-synuclein in both neuroprotection and neurodegeneration Ann N Y Acad Sci 1035 250 270
    • (2004) Ann N Y Acad Sci , vol.1035 , pp. 250-270
    • Sidhu, A.1    Wersinger, C.2    Moussa, C.E.3
  • 37
    • 0141483384 scopus 로고    scopus 로고
    • Measuring correlates of brain metabolism with high-resolution MRI: A promising approach for diagnosing Alzheimer disease and mapping its course
    • SA Small 2003 Measuring correlates of brain metabolism with high-resolution MRI: a promising approach for diagnosing Alzheimer disease and mapping its course Alzheimer Dis Assoc Disord 17 154 161
    • (2003) Alzheimer Dis Assoc Disord , vol.17 , pp. 154-161
    • Small, S.A.1
  • 38
    • 0035789203 scopus 로고    scopus 로고
    • Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
    • CG Specht R Schoepfer 2001 Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice BMC Neurosci 2 11
    • (2001) BMC Neurosci , vol.2 , pp. 11
    • Specht, C.G.1    Schoepfer, R.2
  • 40
    • 0345269239 scopus 로고    scopus 로고
    • Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice
    • JV Steidl T Gomez-Isla A Mariash 2003 Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice Neuroreport 14 219 223
    • (2003) Neuroreport , vol.14 , pp. 219-223
    • Steidl, J.V.1    Gomez-Isla, T.2    Mariash, A.3
  • 41
    • 0030720017 scopus 로고    scopus 로고
    • Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms
    • JH Wang PT Kelly 1997 Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms J Neurophysiol 78 2707 2716
    • (1997) J Neurophysiol , vol.78 , pp. 2707-2716
    • Wang, J.H.1    Kelly, P.T.2
  • 42
    • 10944243102 scopus 로고    scopus 로고
    • Role of alpha-synuclein in presynaptic dopamine recruitment
    • L Yavich H Tanila S Vepsalainen 2004 Role of alpha-synuclein in presynaptic dopamine recruitment J Neurosci 24 11165 11170
    • (2004) J Neurosci , vol.24 , pp. 11165-11170
    • Yavich, L.1    Tanila, H.2    Vepsalainen, S.3
  • 43
    • 26944501221 scopus 로고    scopus 로고
    • Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein
    • L Yavich M Oksman H Tanila 2005 Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein Neurobiol Dis 20 303 313
    • (2005) Neurobiol Dis , vol.20 , pp. 303-313
    • Yavich, L.1    Oksman, M.2    Tanila, H.3
  • 44
    • 20444397428 scopus 로고    scopus 로고
    • Age-related impairments of synaptic plasticity in the lateral perforant path input to the dentate gyrus of galanin overexpressing mice
    • K Zheng E Kuteeva S Xia 2005 Age-related impairments of synaptic plasticity in the lateral perforant path input to the dentate gyrus of galanin overexpressing mice Neuropeptides 39 259 267
    • (2005) Neuropeptides , vol.39 , pp. 259-267
    • Zheng, K.1    Kuteeva, E.2    Xia, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.