-
1
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan MA and Wilson L: Microtubules as a target for anticancer drugs. Nat Rev Cancer 4: 253-265, 2004.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
2
-
-
20444481591
-
Proteomic analysis of anti-cancer effects by paclitaxel treatment in cervical cancer cells
-
Lee KH, Yim EK, Kim CJ, Namkoong SE, Um SJ and Park JS: Proteomic analysis of anti-cancer effects by paclitaxel treatment in cervical cancer cells. Gynecol Oncol 98: 45-53, 2005.
-
(2005)
Gynecol Oncol
, vol.98
, pp. 45-53
-
-
Lee, K.H.1
Yim, E.K.2
Kim, C.J.3
Namkoong, S.E.4
Um, S.J.5
Park, J.S.6
-
3
-
-
16844378550
-
The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance
-
Ferlini C, Raspaglio G, Mozzetti S, et al: The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance. Cancer Res 65: 2397-2405, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 2397-2405
-
-
Ferlini, C.1
Raspaglio, G.2
Mozzetti, S.3
-
4
-
-
1342287839
-
Do beta-tubulin mutations have a role in resistance to chemotherapy?
-
Berrieman HK, Lind MJ and Cawkwell L: Do beta-tubulin mutations have a role in resistance to chemotherapy? Lancet Oncol 5: 158-164, 2004.
-
(2004)
Lancet Oncol
, vol.5
, pp. 158-164
-
-
Berrieman, H.K.1
Lind, M.J.2
Cawkwell, L.3
-
5
-
-
0031974895
-
Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes
-
van Ark-Otte J, Samelis G, Rubio G, Lopez Saez JB, Pinedo HM and Giaccone G: Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes. Oncol Rep 5: 249-255, 1998.
-
(1998)
Oncol Rep
, vol.5
, pp. 249-255
-
-
van Ark-Otte, J.1
Samelis, G.2
Rubio, G.3
Lopez Saez, J.B.4
Pinedo, H.M.5
Giaccone, G.6
-
6
-
-
0035949576
-
Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics
-
Goncalves A, Braguer D, Kamath K, et al: Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics. Proc Natl Acad Sci USA 98: 11737-11742, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11737-11742
-
-
Goncalves, A.1
Braguer, D.2
Kamath, K.3
-
7
-
-
33847192750
-
Gene expression profiling of paired ovarian tumors obtained prior to and following adjuvant chemotherapy: Molecular signatures of chemoresistant tumors
-
L'Esperance S, Popa I, Bachvarova M, et al: Gene expression profiling of paired ovarian tumors obtained prior to and following adjuvant chemotherapy: molecular signatures of chemoresistant tumors. Int J Oncol 29: 5-24, 2006.
-
(2006)
Int J Oncol
, vol.29
, pp. 5-24
-
-
L'Esperance, S.1
Popa, I.2
Bachvarova, M.3
-
8
-
-
0033536197
-
Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon
-
Still IH, Hamilton M, Vince P, Wolfman A and Cowell JK: Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon. Oncogene 18: 4032-4038, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 4032-4038
-
-
Still, I.H.1
Hamilton, M.2
Vince, P.3
Wolfman, A.4
Cowell, J.K.5
-
9
-
-
0033152107
-
The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines
-
Still IH, Vince P and Cowell JK: The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines. Genomics 58: 165-170, 1999.
-
(1999)
Genomics
, vol.58
, pp. 165-170
-
-
Still, I.H.1
Vince, P.2
Cowell, J.K.3
-
10
-
-
0035044693
-
Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/ TACC3, identified in erythroid precursor cells
-
McKeveney PJ, Hodges VM, Mullan RN, et al: Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/ TACC3, identified in erythroid precursor cells. Br J Haematol 112: 1016-1024, 2001.
-
(2001)
Br J Haematol
, vol.112
, pp. 1016-1024
-
-
McKeveney, P.J.1
Hodges, V.M.2
Mullan, R.N.3
-
11
-
-
0037083734
-
The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis
-
Piekorz RP, Hoffmeyer A, Duntsch CD, et al: The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis. EMBO J 21: 653-664, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 653-664
-
-
Piekorz, R.P.1
Hoffmeyer, A.2
Duntsch, C.D.3
-
12
-
-
37849038558
-
TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest
-
Schneider L, Essmann F, Kletke A, et al: TACC3 depletion sensitizes to paclitaxel-induced cell death and overrides p21WAF-mediated cell cycle arrest. Oncogene 27: 116-125, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 116-125
-
-
Schneider, L.1
Essmann, F.2
Kletke, A.3
-
13
-
-
0031036695
-
p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel
-
Debernardis D, Sire EG, De Feudis P, et al: p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel. Cancer Res 57: 870-874, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 870-874
-
-
Debernardis, D.1
Sire, E.G.2
De Feudis, P.3
-
14
-
-
38649135366
-
Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol
-
Gagnon V, Van Themsche C, Turner S, Leblanc V and Asselin E: Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol. Apoptosis 13: 259-271, 2008.
-
(2008)
Apoptosis
, vol.13
, pp. 259-271
-
-
Gagnon, V.1
Van Themsche, C.2
Turner, S.3
Leblanc, V.4
Asselin, E.5
-
15
-
-
57149138181
-
RNA Interference-mediated silencing of the polo-like kinase 1 gene enhances chemosensitivity to gemcitabine in pancreatic adenocarcinoma cells
-
In press
-
Yu C, Zhang X, Sun G, et al: RNA Interference-mediated silencing of the polo-like kinase 1 gene enhances chemosensitivity to gemcitabine in pancreatic adenocarcinoma cells. J Cell Mol Med (In press).
-
J Cell Mol Med
-
-
Yu, C.1
Zhang, X.2
Sun, G.3
-
16
-
-
40349091426
-
p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4
-
Quan H, Xu Y and Lou L: p38 MAPK, but not ERK1/2, is critically involved in the cytotoxicity of the novel vascular disrupting agent combretastatin A4. Int J Cancer 122: 1730-1737, 2008.
-
(2008)
Int J Cancer
, vol.122
, pp. 1730-1737
-
-
Quan, H.1
Xu, Y.2
Lou, L.3
-
17
-
-
23844519729
-
Gene expression analysis of pancreatic cell lines reveals genes overexpressed in pancreatic cancer
-
Alldinger I, Dittert D, Peiper M, et al: Gene expression analysis of pancreatic cell lines reveals genes overexpressed in pancreatic cancer. Pancreatology 5: 370-379, 2005.
-
(2005)
Pancreatology
, vol.5
, pp. 370-379
-
-
Alldinger, I.1
Dittert, D.2
Peiper, M.3
-
18
-
-
36148968005
-
Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma
-
Yu GR, Kim SH, Park SH, et al: Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma. Exp Mol Med 39: 641-652, 2007.
-
(2007)
Exp Mol Med
, vol.39
, pp. 641-652
-
-
Yu, G.R.1
Kim, S.H.2
Park, S.H.3
-
19
-
-
48149112465
-
Urokinase receptor splice variant uPAR-del4/5-associated gene expression in breast cancer: Identification of rab31 as an independent prognostic factor
-
Kotzsch M, Sieuwerts AM, Grosser M, et al: Urokinase receptor splice variant uPAR-del4/5-associated gene expression in breast cancer: identification of rab31 as an independent prognostic factor. Breast Cancer Res Treat 111: 229-240, 2008.
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 229-240
-
-
Kotzsch, M.1
Sieuwerts, A.M.2
Grosser, M.3
-
20
-
-
8744250174
-
Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion
-
Spinella F, Rosano L, Di Castro V, Natali PG and Bagnato A: Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion. J Biol Chem 279: 46700-46705, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 46700-46705
-
-
Spinella, F.1
Rosano, L.2
Di Castro, V.3
Natali, P.G.4
Bagnato, A.5
-
21
-
-
28644448228
-
Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth
-
Jenkins Y, Markovtsov V, Lang W, et al: Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth. Mol Biol Cell 16: 5621-5629, 2005.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5621-5629
-
-
Jenkins, Y.1
Markovtsov, V.2
Lang, W.3
-
22
-
-
0037370649
-
Angiogenesis: Vascular remodeling of the extracellular matrix involves metalloproteinases
-
Heissig B, Hattori K, Friedrich M, Rafii S and Werb Z: Angiogenesis: vascular remodeling of the extracellular matrix involves metalloproteinases. Curr Opin Hematol 10: 136-141, 2003.
-
(2003)
Curr Opin Hematol
, vol.10
, pp. 136-141
-
-
Heissig, B.1
Hattori, K.2
Friedrich, M.3
Rafii, S.4
Werb, Z.5
-
23
-
-
39849100541
-
Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: Role of bone marrow-derived myelomonocytic cells
-
Ahn GO and Brown JM: Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 13: 193-205, 2008.
-
(2008)
Cancer Cell
, vol.13
, pp. 193-205
-
-
Ahn, G.O.1
Brown, J.M.2
-
24
-
-
33746397518
-
Platelet-endothelial cell adhesion molecule-1 (CD31) recycles and induces cell growth inhibition on human tumor cell lines
-
Lutzky VP, Carnevale RP, Alvarez MJ, et al: Platelet-endothelial cell adhesion molecule-1 (CD31) recycles and induces cell growth inhibition on human tumor cell lines. J Cell Biochem 98: 1334-1350, 2006.
-
(2006)
J Cell Biochem
, vol.98
, pp. 1334-1350
-
-
Lutzky, V.P.1
Carnevale, R.P.2
Alvarez, M.J.3
-
25
-
-
0035901938
-
Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance
-
Friedrich K, Wieder T, Von Haefen C, et al: Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene 20: 2749-2760, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 2749-2760
-
-
Friedrich, K.1
Wieder, T.2
Von Haefen, C.3
-
26
-
-
16844376641
-
Elevated physiologic tumor pressure promotes proliferation and chemosensitivity in human osteosarcoma
-
Nathan SS, DiResta GR, Casas-Ganem JE, et al: Elevated physiologic tumor pressure promotes proliferation and chemosensitivity in human osteosarcoma. Clin Cancer Res 11: 2389-2397, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2389-2397
-
-
Nathan, S.S.1
DiResta, G.R.2
Casas-Ganem, J.E.3
-
27
-
-
0037326983
-
Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor
-
Hellawell GO, Ferguson DJ, Brewster SF and Macaulay VM: Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor. BJU Int 91: 271-277, 2003.
-
(2003)
BJU Int
, vol.91
, pp. 271-277
-
-
Hellawell, G.O.1
Ferguson, D.J.2
Brewster, S.F.3
Macaulay, V.M.4
-
28
-
-
0029328641
-
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway
-
Woods CM, Zhu J, McQueney PA, Bollag D and Lazarides E: Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway. Mol Med 1: 506-526, 1995.
-
(1995)
Mol Med
, vol.1
, pp. 506-526
-
-
Woods, C.M.1
Zhu, J.2
McQueney, P.A.3
Bollag, D.4
Lazarides, E.5
-
29
-
-
0030020158
-
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
-
Jordan MA, Wendell K, Gardiner S, Derry WB, Copp H and Wilson L: Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 56: 816-825, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 816-825
-
-
Jordan, M.A.1
Wendell, K.2
Gardiner, S.3
Derry, W.B.4
Copp, H.5
Wilson, L.6
-
30
-
-
0034212385
-
Paclitaxel-induced cell death: Where the cell cycle and apoptosis come together
-
Wang TH, Wang HS and Soong YK: Paclitaxel-induced cell death: where the cell cycle and apoptosis come together. Cancer 88: 2619-2628, 2000.
-
(2000)
Cancer
, vol.88
, pp. 2619-2628
-
-
Wang, T.H.1
Wang, H.S.2
Soong, Y.K.3
-
31
-
-
0034687657
-
The TACC domain identifies a family of centrosomal proteins that can interact with microtubules
-
Gergely F, Karlsson C, Still I, Cowell J, Kilmartin J and Raff JW: The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. Proc Natl Acad Sci USA 97: 14352-14357, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 14352-14357
-
-
Gergely, F.1
Karlsson, C.2
Still, I.3
Cowell, J.4
Kilmartin, J.5
Raff, J.W.6
-
32
-
-
25444493845
-
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
-
Kinoshita K, Noetzel TL, Pelletier L, et al: Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol 170: 1047-1055, 2005.
-
(2005)
J Cell Biol
, vol.170
, pp. 1047-1055
-
-
Kinoshita, K.1
Noetzel, T.L.2
Pelletier, L.3
-
33
-
-
27144540976
-
Centrosome amplification, chromosome instability and cancer development
-
Fukasawa K: Centrosome amplification, chromosome instability and cancer development. Cancer Lett 230: 6-19, 2005.
-
(2005)
Cancer Lett
, vol.230
, pp. 6-19
-
-
Fukasawa, K.1
-
34
-
-
0037314330
-
The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells
-
Gergely F, Draviam VM and Raff JW: The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells. Genes Dev 17: 336-341, 2003.
-
(2003)
Genes Dev
, vol.17
, pp. 336-341
-
-
Gergely, F.1
Draviam, V.M.2
Raff, J.W.3
-
35
-
-
35748974183
-
The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival
-
Schneider L, Essmann F, Kletke A, et al: The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival. J Biol Chem 282: 29273-29283, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 29273-29283
-
-
Schneider, L.1
Essmann, F.2
Kletke, A.3
-
36
-
-
0035963277
-
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: Molecular determinants of paclitaxel-induced cytotoxicity
-
Giannakakou P, Robey R, Fojo T and Blagosklonny MV: Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity. Oncogene 20: 3806-3813, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 3806-3813
-
-
Giannakakou, P.1
Robey, R.2
Fojo, T.3
Blagosklonny, M.V.4
-
37
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M and Harris CC: Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54: 4855-4878, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
38
-
-
0031953822
-
Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment
-
Fan S, Cherney B, Reinhold W, Rucker K and O'Connor PM: Disruption of p53 function in immortalized human cells does not affect survival or apoptosis after taxol or vincristine treatment. Clin Cancer Res 4: 1047-1054, 1998.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1047-1054
-
-
Fan, S.1
Cherney, B.2
Reinhold, W.3
Rucker, K.4
O'Connor, P.M.5
-
39
-
-
0035843123
-
Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53
-
Bacus SS, Gudkov AV, Lowe M, et al: Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53. Oncogene 20: 147-155, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 147-155
-
-
Bacus, S.S.1
Gudkov, A.V.2
Lowe, M.3
-
40
-
-
0037444380
-
Selective Akt inactivation and tumor necrosis factor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel
-
Asakuma J, Sumitomo M, Asano T, Asano T and Hayakawa M: Selective Akt inactivation and tumor necrosis factor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel. Cancer Res 63: 1365-1370, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 1365-1370
-
-
Asakuma, J.1
Sumitomo, M.2
Asano, T.3
Asano, T.4
Hayakawa, M.5
|