DNA binding ellipticine analogues: Synthesis, biological evaluation, and structure-activity relationships

ChemMedChem

Volumn 4, Issue 3, 2009, Pages 363-377

  Ferlin, Maria Grazia ^a   Marzano, Christine ^a   Gandin, Valentina ^a   Dall'Acqua, Stefano ^a   Dalla Via, Lisa ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Antitumor agents; DNA; Pyridocarbazoles; Pyrroloquinolines; Topoisomerase inhibitors

Indexed keywords

1 (2 DIETHYLAMINOETHOXY) 7 (2 DIETHYLAMINOETHYL) 6 METHOXY 3 METHYL 7H PYRIDO[2,3 C]CARBAZOLE; CASPASE 3; CISPLATIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ELLIPTICINE; ELLIPTICINE DERIVATIVE; MITOXANTRONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DNA DETERMINATION; DRUG ACTIVITY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LINEAR DICHROISM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARBAZOLES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; DNA TOPOISOMERASES, TYPE II; ELLIPTICINES; HUMANS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 62749188305     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800368     Document Type: Article

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