Purification and properties of ghrelin from the intestine of the goldfish, Carassius auratus

Peptides

Volumn 30, Issue 4, 2009, Pages 758-765

  Miura, Tohru ^a   Maruyama, Keisuke ^a   Kaiya, Hiroyuki ^b   Miyazato, Mikiya ^b   Kangawa, Kenji ^b   Uchiyama, Minoru ^a   Shioda, Seiji ^c   Matsuda, Kouhei ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acylation; Ghrelin; Goldfish; Orexigenic action; Purification

Indexed keywords

COMPLEMENTARY DNA; GHRELIN; GROWTH HORMONE; OCTANOIC ACID;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOOD INTAKE; GOLDFISH; GROWTH HORMONE RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION;

ANIMALS; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; FEEDING BEHAVIOR; GHRELIN; GOLDFISH; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENTRICULAR; INTESTINES; RNA, MESSENGER;

CARASSIUS AURATUS; RATTUS;

EID: 62749142520     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2008.12.016     Document Type: Article

References (33)

1. Date Y., Murakami N., Kojima M., Kuroiwa T., Matsukura S., Kangawa K., et al. Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats. Biochem Biophys Res Commun 275 (2000) 477-480
2. Hosoda H., Kojima M., and Kangawa K. Biological, physiological, and pharmacological aspects of ghrelin. J Pharmacol Sci 100 (2006) 398-410
3. Hosoda H., Kojima M., Mizushima T., Shimizu S., and Kangawa K. Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by post-translational processing. J Biol Chem 278 (2003) 64-70
4. Howard A.D., Feighner S.D., Cully D.F., Arena J.P., Liberator P.A., Rosenblum C.I., et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273 (1996) 974-977
5. Isgaard J., Barlind A., and Johansson I. Cardiovascular effects of ghrelin and growth hormone secretagogues. Cardiovascul Hematol Disors Drug Targets 8 (2008) 133-137
6. Kaiya H., Kojima M., Hosoda H., Koda A., Yamamoto K., Kitajima Y., et al. Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue. J Biol Chem 276 (2001) 40441-40448
7. Kaiya H., Kojima M., Hosoda H., Moriyama S., Takahashi A., Kawauchi H., et al. Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. Endocrinology 144 (2003) 5215-5226
8. Kaiya H., Kojima M., Hosoda H., Riley L.G., Hirano T., Grau E.G., et al. Amidated fish ghrelin: purification, cDNA cloning in the Japanese eel and its biological activity. J Endocrinol 176 (2003) 415-423
9. Kaiya H., Kojima M., Hosoda H., Riley L.G., Hirano T., Grau E.G., et al. Identification of tilapia ghrelin and its effects on growth hormone and prolactin release in the tilapia, Oreochromis mossambicus. Comp Biochem Physiol B Biochem Mol Biol 135 (2003) 421-429
10. Kaiya H., Miyazato M., Kangawa K., Peter R.E., and Unniappan S. Ghrelin: A multifunctional hormone in non-mammalian vertebrates. Comp Biochem Physiol A Mol Integr Physiol 149 (2008) 109-128
11. Kaiya H., Sakata I., Kojima M., Hosoda H., Sakai T., and Kangawa K. Structural determination and histochemical localization of ghrelin in the red-eared slider turtle, Trachemys scripta elegans. Gen Comp Endocrinol 138 (2004) 50-57
12. Kaiya H., Small B.C., Bilodeau A.L., Shepherd B.S., Kojima M., Hosoda H., et al. Purification, cDNA cloning, and characterization of ghrelin in channel catfish, Ictalurus punctatus. Gen Comp Endocrinol 143 (2005) 201-210
13. Kawakoshi A., Kaiya H., Riley L.G., Hirano T., Grau E.G., Miyazato M., et al. Identification of a ghrelin-like peptide in two species of shark, Sphyrna lewini and Carcharhinus melanopterus. Gen Comp Endocrinol 151 (2007) 259-268
14. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
15. Matsuda K., Miura T., Kaiya H., Maruyama K., Shimakura S., Uchiyama M., et al. Regulation of food intake by acyl and des-acyl ghrelins in the goldfish. Peptides 27 (2006) 2321-2325
16. Matsuda K., Miura T., Kaiya H., Maruyama K., Uchiyama M., Kangawa K., et al. Stimulatory effect of n-octanoylated ghrelin on locomotor activity in the goldfish, Carassius auratus. Peptides 27 (2006) 1335-1340
17. Matsumoto M., Hosoya H., Kitajima Y., Morozumi N., Minamitake Y., Tanaka S., et al. Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides. Biochem Biophys Res Commun 287 (2001) 142-146
18. Matthews D.J., Goodman L.J., Gorman C.M., and Wells J.A. A survey of furin substrate specificity using substrate phage display. Protein Sci 3 (1994) 1197-1205
19. McKee K.K., Palyha O.C., Feighner S.D., Hreniuk D.L., Tan C.P., Phillips M.S., et al. Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors. Mol Endocrinol 11 (1997) 415-423
20. Miura T., Maruyama K., Shimakura S.I., Kaiya H., Uchiyama M., Kangawa K., et al. Neuropeptide Y mediates ghrelin-induced feeding in the goldfish, Carassius auratus. Neurosci Lett 407 (2006) 279-283
21. Miura T., Maruyama K., Shimakura S., Kaiya H., Uchiyama M., Kangawa K., et al. Regulation of food intake in the goldfish by interaction between ghrelin and orexin. Peptides 28 (2007) 1207-1213
22. Molly S.S., Bresnahan P.A., Leppla S.H., Klimpel K.R., and Thomas G. Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem 267 (1992) 16396-16402
23. Muccioli G., Ghe C., Ghigo M.C., Papotti M., Arvat E., Boghen M.F., et al. Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland. J Endocrinol 157 (1998) 99-106
24. Muccioli G., Papotti M., Locatelli V., Ghigo E., and Deghenghi R. Binding of 125I-labeled ghrelin to membranes from human hypothalamus and pituitary gland. J Endocrinol Invest 24 (2001) RC7-9
25. Nakazato M., Murakami N., Date Y., Kojima M., Matsuo H., Kangawa K., et al. A role for ghrelin in the central regulation of feeding. Nature 409 (2001) 194-198
26. Rouillé Y., Duguay S.J., Lund K., Furuta M., Gong Q., Lipkind G., et al. Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases. Front Neuroendocrinol 16 (1995) 322-361
27. Seoane L.M., Tovar S., Baldelli R., Arvat E., Ghigo E., Casanueva F.F., et al. Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats. Eur J Endocrinol 143 (2000) R7-9
28. Unniappan S., Canosa L.F., and Peter R.E. Orexigenic actions of ghrelin in goldfish: feeding-induced changes in brain and gut mRNA expression and serum levels, and responds to central and peripheral injections. Neuroendocrinology 79 (2004) 100-108
29. Unniappan S., Lin X., Cervini L., Rivier J., Kaiya H., Kangawa K., et al. Goldfish ghrelin: molecular characterization of the complementary deoxyribonucleic acid, partial gene structure and evidence for its stimulatory role in food intake. Endocrinology 143 (2002) 4143-4146
30. Unniappan S., and Peter R.E. In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish. Am J Physiol Regul Integr Comp Physiol 286 (2004) 1093-1101
31. Wren A.M., Small C.J., Ward H.L., Murphy K.G., Dakin C.L., Taheri S., et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141 (2000) 4325-4328
32. Yang J., Brown M.S., Liang G., Grishin N.V., and Goldstein J.L. Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone. Cell 132 (2008) 387-396
33. Zhu X., Cao Y., Voogd K., and Steiner D.F. On the processing of proghrelin to ghrelin. J Biol Chem 281 (2006) 38867-38870