메뉴 건너뛰기




Volumn 83, Issue 6, 2009, Pages 2601-2610

Herpes simplex virus UL12.5 targets mitochondria through a mitochondrial localization sequence proximal to the N terminus

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN D; DEOXYRIBONUCLEASE; DETERGENT; EXONUCLEASE; GENE PRODUCT; MESSENGER RNA; MITOCHONDRIAL DNA; PROTEIN UL12; PROTEIN UL12.5; UNCLASSIFIED DRUG; VIRUS PROTEIN; EXODEOXYRIBONUCLEASE; SIGNAL PEPTIDE; UL12 PROTEIN, HERPES SIMPLEX VIRUS 1;

EID: 62749121074     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02087-08     Document Type: Article
Times cited : (56)

References (41)
  • 1
    • 0023762866 scopus 로고
    • A noncleavable signal for mitochondrial import of 3-oxoacyl-CoA thiolase
    • Amaya, Y., H. Arakawa, M. Takiguchi, Y. Ebina, S. Yokota, and M. Mori. 1988. A noncleavable signal for mitochondrial import of 3-oxoacyl-CoA thiolase. J. Biol. Chem. 263:14463-14470.
    • (1988) J. Biol. Chem , vol.263 , pp. 14463-14470
    • Amaya, Y.1    Arakawa, H.2    Takiguchi, M.3    Ebina, Y.4    Yokota, S.5    Mori, M.6
  • 2
    • 0034664813 scopus 로고    scopus 로고
    • Survey and summary: Holliday junction resolvases and related nucleases: identification of new families, phyletic distribution and evolutionary trajectories
    • Aravind, L., K. S. Makarova, and E. V. Koonin. 2000. Survey and summary: holliday junction resolvases and related nucleases: identification of new families, phyletic distribution and evolutionary trajectories. Nucleic Acids Res. 28:3417-3432.
    • (2000) Nucleic Acids Res , vol.28 , pp. 3417-3432
    • Aravind, L.1    Makarova, K.S.2    Koonin, E.V.3
  • 3
    • 12344293822 scopus 로고    scopus 로고
    • Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining
    • Ashley, N., D. Harris, and J. Poulton. 2005. Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining. Exp. Cell Res. 303:432-446.
    • (2005) Exp. Cell Res , vol.303 , pp. 432-446
    • Ashley, N.1    Harris, D.2    Poulton, J.3
  • 4
    • 0030896672 scopus 로고    scopus 로고
    • The product of the UL12.5 gene of herpes simplex virus type 1 is a capsid-associated nuclease
    • Bronstein, J. C., S. K. Weiler, and P. C. Weber. 1997. The product of the UL12.5 gene of herpes simplex virus type 1 is a capsid-associated nuclease. J. Virol. 71:3039-3047.
    • (1997) J. Virol , vol.71 , pp. 3039-3047
    • Bronstein, J.C.1    Weiler, S.K.2    Weber, P.C.3
  • 5
    • 0029915525 scopus 로고    scopus 로고
    • Computational method to predict mitochondrially imported proteins and their targeting sequences
    • Claros, M. G., and P. Vincens. 1996. Computational method to predict mitochondrially imported proteins and their targeting sequences. Eur. J. Biochem. 241:779-786.
    • (1996) Eur. J. Biochem , vol.241 , pp. 779-786
    • Claros, M.G.1    Vincens, P.2
  • 6
    • 33748930095 scopus 로고    scopus 로고
    • Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene
    • Corcoran, J. A., W. L. Hsu, and J. R. Smiley. 2006. Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene. J. Virol. 80:9720-9729.
    • (2006) J. Virol , vol.80 , pp. 9720-9729
    • Corcoran, J.A.1    Hsu, W.L.2    Smiley, J.R.3
  • 7
    • 0021061053 scopus 로고
    • High-resolution characterization of herpes simplex virus type 1 transcripts encoding alkaline exonuclease and a 50,000-dalton protein tentatively identified as a capsid protein
    • Costa, R. H., K. G. Draper, L. Banks, K. L. Powell, G. Cohen, R. Eisenberg, and E. K. Wagner. 1983. High-resolution characterization of herpes simplex virus type 1 transcripts encoding alkaline exonuclease and a 50,000-dalton protein tentatively identified as a capsid protein. J. Virol. 48:591-603.
    • (1983) J. Virol , vol.48 , pp. 591-603
    • Costa, R.H.1    Draper, K.G.2    Banks, L.3    Powell, K.L.4    Cohen, G.5    Eisenberg, R.6    Wagner, E.K.7
  • 8
    • 9744242736 scopus 로고    scopus 로고
    • Mitochondrial medicine
    • Dimauro, S. 2004. Mitochondrial medicine. Biochim. Biophys. Acta 1659: 107-114.
    • (2004) Biochim. Biophys. Acta , vol.1659 , pp. 107-114
    • Dimauro, S.1
  • 9
    • 0022633660 scopus 로고
    • Characterization of the genes encoding herpes simplex virus type 1 and type 2 alkaline exonucleases and overlapping proteins
    • Draper, K. G., G. Devi-Rao, R. H. Costa, E. D. Blair, R. L. Thompson, and E. K. Wagner. 1986. Characterization of the genes encoding herpes simplex virus type 1 and type 2 alkaline exonucleases and overlapping proteins. J. Virol. 57:1023-1036.
    • (1986) J. Virol , vol.57 , pp. 1023-1036
    • Draper, K.G.1    Devi-Rao, G.2    Costa, R.H.3    Blair, E.D.4    Thompson, R.L.5    Wagner, E.K.6
  • 10
    • 0037252462 scopus 로고    scopus 로고
    • Replication and transcription of mammalian mitochondrial DNA
    • Fernández-Silva, P., J. A. Enriquez, and J. Montoya. 2003. Replication and transcription of mammalian mitochondrial DNA. Exp. Physiol. 88:41-56.
    • (2003) Exp. Physiol , vol.88 , pp. 41-56
    • Fernández-Silva, P.1    Enriquez, J.A.2    Montoya, J.3
  • 11
    • 0031588987 scopus 로고    scopus 로고
    • Cloning and expression of cDNA for a newly identified isozyme of bovine liver 3-hydroxyacyl-CoA dehydrogenase and its import into mitochondria
    • Furuta, S., A. Kobayashi, S. Miyazawa, and T. Hashimoto. 1997. Cloning and expression of cDNA for a newly identified isozyme of bovine liver 3-hydroxyacyl-CoA dehydrogenase and its import into mitochondria. Biochim. Biophys. Acta 1350:317-324.
    • (1997) Biochim. Biophys. Acta , vol.1350 , pp. 317-324
    • Furuta, S.1    Kobayashi, A.2    Miyazawa, S.3    Hashimoto, T.4
  • 12
    • 0031713687 scopus 로고    scopus 로고
    • In vitro processing of herpes simplex virus type 1 DNA replication intermediates by the viral alkaline nuclease, UL12
    • Goldstein, J. N., and S. K. Weiler. 1998. In vitro processing of herpes simplex virus type 1 DNA replication intermediates by the viral alkaline nuclease, UL12. J. Virol. 72:8772-8781.
    • (1998) J. Virol , vol.72 , pp. 8772-8781
    • Goldstein, J.N.1    Weiler, S.K.2
  • 13
    • 0032503242 scopus 로고    scopus 로고
    • The exonuclease activity of HSV-1 UL12 is required for in vivo function
    • Goldstein, J. N, and S. K. Weiler. 1998. The exonuclease activity of HSV-1 UL12 is required for in vivo function. Virology 244:442-457.
    • (1998) Virology , vol.244 , pp. 442-457
    • Goldstein, J.N.1    Weiler, S.K.2
  • 14
    • 0032579808 scopus 로고    scopus 로고
    • Structure-function analysis of the herpes simplex virus type 1 UL12 gene: Correlation of deoxyribonuclease activity in vitro with replication function
    • Henderson, J. O., L. J. Ball-Goodrich, and D. S. Parris. 1998. Structure-function analysis of the herpes simplex virus type 1 UL12 gene: correlation of deoxyribonuclease activity in vitro with replication function. Virology 243:247-259.
    • (1998) Virology , vol.243 , pp. 247-259
    • Henderson, J.O.1    Ball-Goodrich, L.J.2    Parris, D.S.3
  • 15
    • 0019460827 scopus 로고
    • Mechanism of degradation of duplex DNA by the DNase induced by herpes simplex virus
    • Hoffmann, P. J. 1981. Mechanism of degradation of duplex DNA by the DNase induced by herpes simplex virus. J. Virol. 38:1005-1014.
    • (1981) J. Virol , vol.38 , pp. 1005-1014
    • Hoffmann, P.J.1
  • 16
    • 0018143471 scopus 로고
    • The deoxyribonuclease induced after infection of KB cells by herpes simplex virus type 1 or type 2. I. Purification and characterization of the enzyme
    • Hoffmann, P. J., and Y. C. Cheng. 1978. The deoxyribonuclease induced after infection of KB cells by herpes simplex virus type 1 or type 2. I. Purification and characterization of the enzyme. J. Biol. Chem. 253:3557-3562.
    • (1978) J. Biol. Chem , vol.253 , pp. 3557-3562
    • Hoffmann, P.J.1    Cheng, Y.C.2
  • 17
    • 0025299332 scopus 로고
    • Comparison of exonucleolytic activities of herpes simplex virus type-1 DNA polymerase and DNase
    • Knopf, C. W., and K. Weisshart. 1990. Comparison of exonucleolytic activities of herpes simplex virus type-1 DNA polymerase and DNase. Eur. J. Biochem. 191:263-273.
    • (1990) Eur. J. Biochem , vol.191 , pp. 263-273
    • Knopf, C.W.1    Weisshart, K.2
  • 18
    • 0027229230 scopus 로고
    • EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif
    • Ling, P. D., J. J. Ryon, and S. D. Hayward. 1993. EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif. J. Virol. 67:2990-3003.
    • (1993) J. Virol , vol.67 , pp. 2990-3003
    • Ling, P.D.1    Ryon, J.J.2    Hayward, S.D.3
  • 19
    • 0036376718 scopus 로고    scopus 로고
    • The product of the UL12.5 gene of herpes simplex virus type 1 is not essential for lytic viral growth and is not specifically associated with capsids
    • Martinez, R., J. N. Goldstein, and S. K. Weiler. 2002. The product of the UL12.5 gene of herpes simplex virus type 1 is not essential for lytic viral growth and is not specifically associated with capsids. Virology 298:248-257.
    • (2002) Virology , vol.298 , pp. 248-257
    • Martinez, R.1    Goldstein, J.N.2    Weiler, S.K.3
  • 20
    • 0029870883 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates
    • Martinez, R., R. T. Sarisky, P. C. Weber, and S. K. Weiler. 1996. Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates. J. Virol. 70:2075-2085.
    • (1996) J. Virol , vol.70 , pp. 2075-2085
    • Martinez, R.1    Sarisky, R.T.2    Weber, P.C.3    Weiler, S.K.4
  • 21
    • 0030042028 scopus 로고    scopus 로고
    • The product of a 1.9-kb mRNA which overlaps the HSV-1 alkaline nuclease gene (UL12) cannot relieve the growth defects of a null mutant
    • Martinez, R., L. Shao, J. C. Bronstein, P. C. Weber, and S. K. Weiler. 1996. The product of a 1.9-kb mRNA which overlaps the HSV-1 alkaline nuclease gene (UL12) cannot relieve the growth defects of a null mutant. Virology 215:152-164.
    • (1996) Virology , vol.215 , pp. 152-164
    • Martinez, R.1    Shao, L.2    Bronstein, J.C.3    Weber, P.C.4    Weiler, S.K.5
  • 22
    • 0023056612 scopus 로고
    • DNA sequence of the region in the genome of herpes simplex virus type 1 containing the exonuclease gene and neighbouring genes
    • McGeoch, D. J., A. Dolan, and M. C. Frame. 1986. DNA sequence of the region in the genome of herpes simplex virus type 1 containing the exonuclease gene and neighbouring genes. Nucleic Acids Res. 14:3435-3448.
    • (1986) Nucleic Acids Res , vol.14 , pp. 3435-3448
    • McGeoch, D.J.1    Dolan, A.2    Frame, M.C.3
  • 23
    • 0033624563 scopus 로고    scopus 로고
    • RecE/RecT and Redalpha/Redbeta initiate double-stranded break repair by specifically interacting with their respective partners
    • Muyrers, J. P., Y. Zhang, F. Buchholz, and A. F. Stewart. 2000. RecE/RecT and Redalpha/Redbeta initiate double-stranded break repair by specifically interacting with their respective partners. Genes Dev. 14:1971-1982.
    • (2000) Genes Dev , vol.14 , pp. 1971-1982
    • Muyrers, J.P.1    Zhang, Y.2    Buchholz, F.3    Stewart, A.F.4
  • 24
    • 0002748070 scopus 로고    scopus 로고
    • Mining DNA sequences for molecular enzymology: The Reda superfamily defines a set of DNA recombinase nucle-ases
    • Oxford University Press, Oxford, United Kingdom
    • Myers, R. S., and K. E. Rudd. 1998. Mining DNA sequences for molecular enzymology: the Reda superfamily defines a set of DNA recombinase nucle-ases, p. 49-50. Proceedings of the 1998 Miami Nature Biotechnology Winter Symposium. Oxford University Press, Oxford, United Kingdom.
    • (1998) Proceedings of the 1998 Miami Nature Biotechnology Winter Symposium , pp. 49-50
    • Myers, R.S.1    Rudd, K.E.2
  • 25
    • 0031799733 scopus 로고    scopus 로고
    • Mitochondria-targeting sequence, a multi-role sorting sequence recognized at all steps of protein import into mitochondria
    • Omura, T. 1998. Mitochondria-targeting sequence, a multi-role sorting sequence recognized at all steps of protein import into mitochondria. J. Bio-chem. 123:1010-1016.
    • (1998) J. Bio-chem , vol.123 , pp. 1010-1016
    • Omura, T.1
  • 26
    • 4143103158 scopus 로고    scopus 로고
    • The UL12.5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus
    • Reuven, N. B., S. Antoku, and S. K. Weller. 2004. The UL12.5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus. J. Virol. 78:4599-4608.
    • (2004) J. Virol , vol.78 , pp. 4599-4608
    • Reuven, N.B.1    Antoku, S.2    Weller, S.K.3
  • 27
    • 0038468334 scopus 로고    scopus 로고
    • The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitro
    • Reuven, N. B., A. E. Staire, R. S. Myers, and S. K. Weiler. 2003. The herpes simplex virus type 1 alkaline nuclease and single-stranded DNA binding protein mediate strand exchange in vitro. J. Virol. 77:7425-7433.
    • (2003) J. Virol , vol.77 , pp. 7425-7433
    • Reuven, N.B.1    Staire, A.E.2    Myers, R.S.3    Weiler, S.K.4
  • 28
    • 4143140939 scopus 로고    scopus 로고
    • Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: Potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease
    • Reuven, N. B., S. Willcox, J. D. Griffith, and S. K. Weiler. 2004. Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease. J. Mol. Biol. 342:57-71.
    • (2004) J. Mol. Biol , vol.342 , pp. 57-71
    • Reuven, N.B.1    Willcox, S.2    Griffith, J.D.3    Weiler, S.K.4
  • 29
    • 0022546215 scopus 로고
    • Nuclear location signals in polyoma virus large-T
    • Richardson, W. D., B. L. Roberts, and A. E. Smith. 1986. Nuclear location signals in polyoma virus large-T. Cell 44:77-85.
    • (1986) Cell , vol.44 , pp. 77-85
    • Richardson, W.D.1    Roberts, B.L.2    Smith, A.E.3
  • 30
    • 0028157317 scopus 로고
    • Isolation of a cDNA clone specifying rat chaperonin 10, a stress-inducible mitochondrial matrix protein synthesised without a cleavable presequence
    • Ryan, M. T., N. J. Hoogenraad, and P. B. Hoj. 1994. Isolation of a cDNA clone specifying rat chaperonin 10, a stress-inducible mitochondrial matrix protein synthesised without a cleavable presequence. FEBS Lett. 337:152-156.
    • (1994) FEBS Lett , vol.337 , pp. 152-156
    • Ryan, M.T.1    Hoogenraad, N.J.2    Hoj, P.B.3
  • 32
    • 0014310452 scopus 로고
    • Enzymatic properties of the inner and outer membranes of rat liver mitochondria
    • Schnaitman, C., and J. W. Greenawalt. 1968. Enzymatic properties of the inner and outer membranes of rat liver mitochondria. J. Cell Biol. 38:158-175.
    • (1968) J. Cell Biol , vol.38 , pp. 158-175
    • Schnaitman, C.1    Greenawalt, J.W.2
  • 33
    • 0030920779 scopus 로고    scopus 로고
    • Mitochondrial DNA maintenance in vertebrates
    • Shadel, G. S, and D. A. Clayton. 1997. Mitochondrial DNA maintenance in vertebrates. Annu. Rev. Biochem. 66:409-435.
    • (1997) Annu. Rev. Biochem , vol.66 , pp. 409-435
    • Shadel, G.S.1    Clayton, D.A.2
  • 34
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
    • Shaner, N. C., R. E. Campbell, P. A. Steinbach, B. N. Giepmans, A. E. Palmer, and R. Y. Tsien. 2004. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22:1567-1572.
    • (2004) Nat. Biotechnol , vol.22 , pp. 1567-1572
    • Shaner, N.C.1    Campbell, R.E.2    Steinbach, P.A.3    Giepmans, B.N.4    Palmer, A.E.5    Tsien, R.Y.6
  • 35
    • 0027227461 scopus 로고
    • Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus
    • Shao, L., L. M. Rapp, and S. K. Weiler. 1993. Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus. Virology 196:146-162.
    • (1993) Virology , vol.196 , pp. 146-162
    • Shao, L.1    Rapp, L.M.2    Weiler, S.K.3
  • 36
    • 0018855589 scopus 로고
    • Alkaline, deoxyribonuclease induced by herpes simplex virus type 1: Composition and properties of the purified enzyme
    • Strobel-Fidler, M, and B. Fracike. 1980. Alkaline, deoxyribonuclease induced by herpes simplex virus type 1: composition and properties of the purified enzyme. Virology 103:493-501.
    • (1980) Virology , vol.103 , pp. 493-501
    • Strobel-Fidler, M.1    Fracike, B.2
  • 37
    • 0026540993 scopus 로고
    • Association between the herpes simplex virus major DNA-binding protein and alkaline nuclease
    • Thomas, M. S, M. Gao, D. M. Knipt, and K. L. Powell. 1992. Association between the herpes simplex virus major DNA-binding protein and alkaline nuclease. J. Virol. 66:1152-1161.
    • (1992) J. Virol , vol.66 , pp. 1152-1161
    • Thomas, M.S.1    Gao, M.2    Knipt, D.M.3    Powell, K.L.4
  • 38
    • 0037447049 scopus 로고    scopus 로고
    • Mechanisms of protein import into mitochondria
    • Truscott, K. N., K. Brandner, and N. Pfanner. 2003. Mechanisms of protein import into mitochondria. Curr. Biol. 13:R326-R337.
    • (2003) Curr. Biol , vol.13
    • Truscott, K.N.1    Brandner, K.2    Pfanner, N.3
  • 39
    • 0021685230 scopus 로고
    • Interactions between herpes simplex virus DNA-binding proteins
    • Vaughan, P. J., L. M. Banks, D. J. Purifoy, and K. L. Powell. 1984. Interactions between herpes simplex virus DNA-binding proteins. J. Gen. Virol. 65:2033-2041.
    • (1984) J. Gen. Virol , vol.65 , pp. 2033-2041
    • Vaughan, P.J.1    Banks, L.M.2    Purifoy, D.J.3    Powell, K.L.4
  • 40
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • Wallace, D. C. 2005. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39:359-407.
    • (2005) Annu. Rev. Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 41
    • 0025667077 scopus 로고
    • The herpes simplex virus type 1 alkaline nuclease is not essential for viral DNA synthesis: Isolation and characterization of a lacZ insertion mutant
    • Weiler, S. K., M. R. Seghatoleslami, L. Shao, D. Rowse, and E. P. Car-michael. 1990. The herpes simplex virus type 1 alkaline nuclease is not essential for viral DNA synthesis: isolation and characterization of a lacZ insertion mutant. J. Gen. Virol. 71:2941-2952.
    • (1990) J. Gen. Virol , vol.71 , pp. 2941-2952
    • Weiler, S.K.1    Seghatoleslami, M.R.2    Shao, L.3    Rowse, D.4    Car-michael, E.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.