Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae)

Memorias do Instituto Oswaldo Cruz

Volumn 104, Issue 1, 2009, Pages 48-55

  Silva, Ellen C C ^a,b   Cavalcanti, Bruno C ^d   Amorim, Rodrigo C N ^a,b   Lucena, Jorcilene F ^a,b   Quadros, Dulcimar S ^a,e   Tadei, Wanderli P ^c   Montenegro, Raquel C ^d   Costa Lotufo, Letícia V ^d   Pessoa, Cláudia ^d   Moraes, Manoel O ^d   Nunomura, Rita C S ^a   Nunomura, Sergio M ^a   Melo, Marcia R S ^a   de Andrade Neto, Valter F ^a   Silva, Luiz Franciso R ^b,f   Vieira, Pedro Paulo R ^f   Pohlit, Adrian M ^a  

^a Laboratório de Princípios Ativos da Amazônia   (Brazil)

^b FEDERAL UNIVERSITY OF AMAZONAS   (Brazil)

^c INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA   (Brazil)

^d FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^e INSTITUTO FEDERAL DE EDUCAÇÃO   (Brazil)

^f FUNDAÇÃO DE MEDICINA TROPICAL DR HEITOR VIEIRA DOURADO   (Brazil)

Author keywords

1,12 Diacetylisobrucein B; 12 Acetylneosergeolide; Antimalarial; Cytotoxicity; Isobrucein B; Larvicide; Neosergeolide

Indexed keywords

AEDES AEGYPTI; ARTEMIA; ARTEMIA FRANCISCANA; PICROLEMMA; PLASMODIUM FALCIPARUM; SIMAROUBACEAE;

EID: 62749098685     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/s0074-02762009000100008     Document Type: Article

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