A boost in microRNAs shapes up the neuron

EMBO Journal

Volumn 28, Issue 6, 2009, Pages 617-618

  Muddashetty, Ravi ^a   Bassell, Gary J ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; FRAGILE X MENTAL RETARDATION PROTEIN; MICRORNA; POTASSIUM CHLORIDE; RNA BINDING PROTEIN;

ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; DENDRITE; DENDRITIC SPINE; FRAGILE X SYNDROME; GENE CLUSTER; GENE MUTATION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HUMAN; MUSCLE CELL; NERVE CELL; NERVE CELL CULTURE; NERVOUS SYSTEM DEVELOPMENT; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RNA INTERFERENCE; RNA TRANSLATION; SYNAPSE;

ANIMALS; DENDRITES; HUMANS; MADS DOMAIN PROTEINS; MICRORNAS; MYOGENIC REGULATORY FACTORS; NEURONS; ORGANOGENESIS; RATS; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC;

EID: 62649146021     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.51     Document Type: Article

References (11)

1. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297
2. Cheever A, Ceman S (2009) Phosphorylation of FMRP inhibits association with Dicer. RNA (e-pub ahead of print, 20 January 2009; doi: 10.1261/rna.1500809)
3. Fiore R, Khudayberdiev S, Christensen M, Siegel G, Flavell S, Kim TK, Greenberg ME, Schratt G (2009) Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J 28: 697-710
4. Flavell SW, Cowan CW, Kim TK, Greer PL, Lin Y, Paradis S, Griffith EC, Hu LS, Chen C, Greenberg ME (2006) Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311: 1008-1012
5. Flavell SW, Kim TK, Gray JM, Harmin DA, Hemberg M, Hong EJ, Markenscoff-Papadimitriou E, Bear DM, Greenberg ME (2008) Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron 60: 1022-1038
6. Jin P, Alisch RS, Warren ST (2004) RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 6: 1048-1053
7. Kosik KS (2006) The neuronal microRNA system. Nat Rev Neurosci 7: 911-920
8. Kye MJ, Liu T, Levy SF, Xu NL, Groves BB, Bonneau R, Lao K, Kosik KS (2007) Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR. RNA 13: 1224-1234
9. Schratt GM, Tuebing F, Nigh EA, Kane CG, Sabatini ME, Kiebler M, Greenberg ME (2006) A brain-specific microRNA regulates dendritic spine development. Nature 439: 283-289
10. Vessey JP, Vaccani A, Xie Y, Dahm R, Karra D, Kiebler MA, Macchi P (2006) Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules. J Neurosci 26: 6496-6508
11. Xu XL, Li Y, Wang F, Gao FB (2008) The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. J Neurosci 28: 11883-11889