Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate (VC-IP) against ultraviolet-A ray-induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression

Journal of Cellular Biochemistry

Volumn 106, Issue 4, 2009, Pages 589-598

  Xiao, Li ^a   Kaneyasu, Kentaro ^a   Saitoh, Yasukazu ^a   Terashima, Yoichi ^b   Kowata, Yasunori ^c   Miwa, Nobuhiko ^a,d  

^a PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^b TOKYO METROPOLITAN POLICE HOSPITAL   (Japan)

^c NIKKOL Group Cosmos Technical Center Co   (Japan)

^d Faculty of Life and Environmental Sciences   (Japan)

Author keywords

2,3,5,6 O tetra 2 hexyldecanoyl L ascorbic acid; 8 OHdG; Apoptosis; Collagen synthesize; Cytoprotection; MMPs; UVA

Indexed keywords

2,3,5,6 O TETRA 2' HEXYLDECANOYL LEVO ASCORBIC ACID; 8 HYDROXYDEOXYGUANOSINE; ASCORBIC ACID DERIVATIVE; COLLAGEN; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; PHOSPHATIDYLSERINE; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; ULTRAVIOLET A RADIATION;

ASCORBIC ACID; CELL LINE; CELL SURVIVAL; COLLAGEN; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; GLYCOLIPIDS; HUMANS; KERATINOCYTES; MATRIX METALLOPROTEINASES; MELANOMA; SKIN; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

TETRA;

EID: 62649143220     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22032     Document Type: Article

References (25)

1. Agarwal A, Prabakaran SA, Said TM. 2005. Prevention of oxidative stress injury to sperm. J Androl 26:654-660.
2. Besaratinia A, Kim SI, Bates SE, Pfeifer GP. 2007. Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C. Proc Natl Acad Sci USA 104:5953-5958.
3. Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE. 1988. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106:761-771.
4. Fisher GJ, Kang S, Varani J, Bata-Csorgo Z, Wan Y, Datta S, Voorhees JJ. 2002. Mechanisms of photoaging and chronological skin aging. Arch Dermatol 138:1462-1470.
5. Honda A, Abe R, Makino T, Norisugi O, Fujita Y, Watanabe H, Nishihira J, Iwakura Y, Yamagishi S, Shimizu H, Shimizu T. 2008. nterleukin-1beta and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA-induced matrix metalloproteinase-1 expression. J Dermatol Sci 49:63-72.
6. Ichihashi M, Ueda M, Budiyanto A, Bito T, Oka M, Fukunaga M, Tsuru K, Horikawa T. 2003. UV-induced skin damage. Toxicology 189:21-39.
7. Ishiyama M, Tominaga H, Shiga M, Sasamoto K, Ohkura Y, Ueno K. 1996. A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. Biol Pharm Bull 19:1518-1520.
8. Kim JH, Cho YH, Park SM, Lee KE, Lee JJ, Lee BC, Pyo HB, Song KS, Park HD, Yun YP. 2004. Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves of Zostera marina L. Arch Pharm Res 27:177-183.
9. Kimoto T, Koya S, Hino K, Yamamoto Y, Nomura Y, Micallef MJ, Hanaya T, Arai S, Ikeda M, Kurimoto M. 2000. Renal carcinogenesis induced by ferric nitrilotriacetate in mice, and protection from it by Brazilian propolis and artepillin C. Pathol Int 50:679-689.
10. Kurata S, Senoo H, Hata R. 1993. Transcriptional activation of type I collagen genes by ascorbic acid 2-phosphate in human skin fibroblasts and its failure in cells from a patient with alpha 2(I)-chain-defective Ehlers-Danlos syndrome. Exp Cell Res 206:63-71.
11. Liardet S, Scaletta C, Panizzon R, Hohlfeld P, Laurent-Applegate L. 2001. Protection against pyrimidine dimers, p53, and 8-hydroxy-2′- deoxyguanosine expression in ultraviolet-irradiated human skin by sunscreens: Difference between UVB + UVA and UVB alone sunscreens. J Invest Dermatol 117:1437-1441.
12. Marin-Castaño ME, Csaky KG, Cousins SW. 2005. Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity. Invest Ophthalmol Vis Sci 46:3331-3340.
13. Molho-Pessach V, Lotem M. 2007. Ultraviolet radiation and cutaneous carcinogenesis. Curr Probl Dermatol 35:14-27.
14. Nakamura T, Seki S, Matsubara O, Ito S, Kasuga T. 1988. Specific incorporation of 4-S-cysteinylphenol into human melanoma cells. J Invest Dermatol 90:725-728.
15. Negishi T, Kawai K, Arakawa R, Higashi S, Nakamura T, Watanabe M, Kasai H, Fujikawa K. 2007. Increased levels of 8-hydroxy-2′-deoxyguanosine in Drosophila larval DNA after irradiation with 364-nm laser light but not with X-rays. Photochem Photobiol 83:658-663.
16. Ochiai Y, Kaburagi S, Obayashi K, Ujiie N, Hashimoto S, Okano Y, Masaki H, Ichihashi M, Sakurai H. 2006. A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties. J Dermatol Sci 44:37-44.
17. Saied IT, Shamsuddin AM. 1998. Up-regulation of the tumor suppressor gene p53 and WAF1 gene expression by IP6 in HT-29 human colon carcinoma cell line. Anticancer Res 18:1479-1484.
18. Sancéau J, Truchet S, Bauvois B. 2003. Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in Ewing's sarcoma cells. J Biol Chem 278:36537-36546.
19. Sudel KM, Venzke K, Knussmann-Hartig E, Moll I, Stab F, Wenck H, Wittern KP, Gercken G, Gallinat S. 2003. Tight control of matrix metalloproteinase-1 activity in human skin. Photochem Photobiol 78:355-360.
20. Suschek CV, Briviba K, Bruch-Gerharz D, Sies H, Kröncke KD, Kolb-Bachofen V. 2001. Even after UVA-exposure will nitric oxide protect cells from reactive oxygen intermediate-mediated apoptosis and necrosis. Cell Death Differ 8:515-527.
21. Szejda P, Parce JW, Seeds MS, Bass DA. 1984. Flow cytometric quantitation of oxidative product formation by polymorphonuclear leukocytes during phagocytosis. J Immunol 133:3303-3307.
22. Tai A, Kawasaki D, Goto S, Gohda E, Yamamoto I. 2003. Vitamin C activity in guinea pigs of 6-O-acyl-2-O-alpha-D-glucopyranosyl-L-ascorbic acids with a branched-acyl chain. Biosci Biotechnol Biochem 67:1675-1682.
23. Thomas FH, Leask R, Srsen V, Riley SC, Spears N, Telfer EE. 2001. Effect of ascorbic acid on health and morphology of bovine preantral follicles during long-term culture. Reproduction 122:487-495.
24. Wlaschek M, Briviba K, Stricklin GP, Sies H, Scharffetter-Kochanek K. 1995. Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase. J Invest Dermatol 104:194-198.
25. Yu H, Xia Q, Yan J, Herreno-Saenz D, Wu YS, Tang IW, Fu PP. 2006. Photoirradiation of polycyclic aromatic hydrocarbons with UVA light - A pathway leading to the generation of reactive oxygen species, lipid peroxidation, and DNA damage. Int J Environ Res Public Health 3:348-354.