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Volumn 78, Issue 2, 2009, Pages 471-485

Regio- and stereoselective ring-opening reaction of chiral aziridines: A facile synthesis of chiral β-amino alcohols

Author keywords

Amino Alcohol; Chiral Aziridine; Regioselectivity; Ring Opening; Stereoselectivity

Indexed keywords


EID: 62649095819     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-08-11537     Document Type: Article
Times cited : (7)

References (35)
  • 30
    • 62649175270 scopus 로고    scopus 로고
    • X-Ray Crystal structure determinations: A colorless prismatic crystal of C21H27NOBr2 having an approximate dimension of 0.4 x 0.4 x 0.4 mm grown from hexane was used for the data collection of a Rigaku AFC 7R diffractometer with graphic monochromated Cu-Koα radiation, r, 1.54178 Å) and rotating anode generator. Crystal data of 5d, M, 469.26; orthorhombic, space group P212121, 19, Z, 4 with a, 10.979(2) Å, b, 19.261(4) Å, c, 10.289(1) Å, V, 2175.8(6) Å3, and Dcale, 1.432g/cm3. All calculations were performed using the teXsan program. The structure was solved by direct methods and expanded using Fourier techniques. The final R- and Rw-factors after full-matrix least-squares refinement were 0.043 and 0.040, respectively, based on 1475 observed reflections (I>3.00σI
    • w-factors after full-matrix least-squares refinement were 0.043 and 0.040, respectively, based on 1475 observed reflections (I>3.00σ(I)).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.