Magnetic separation of melanoma-specific cytotoxic T lymphocytes from a vaccinated melanoma patient's blood using MHC/peptide complex-conjugated bacterial magnetic particles

Bioconjugate Chemistry

Volumn 20, Issue 2, 2009, Pages 304-309

  Takahashi, Masayuki ^a,b   Akiyama, Yasuto ^a,b   Dcezumi, Junpei ^a,b   Nagata, Takeshi ^a,b   Yoshino, Tomoko ^a,b   Iizuka, Akira ^a,b   Yamaguchi, Ken ^a,b   Matsunaga, Tadashi ^a,b  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b SHIZUOKA CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; BINDING SITES; BLOOD; CELL MEMBRANES; CYTOLOGY; DERMATOLOGY; DISEASES; MAGNETIC SEPARATION; NANOMAGNETICS; NANOPARTICLES; SYNTHESIS (CHEMICAL); T-CELLS;

ANTI VIRUS; BACTERIAL MAGNETIC PARTICLES; CANCER IMMUNOTHERAPY; CELL/B.E; CYTOTOXIC T LYMPHOCYTES; FUNDAMENTAL RESEARCH; IMMUNE CELLS; MAJOR HISTOCOMPATIBILITY COMPLEX; PEPTIDE COMPLEX; STREPTAVIDIN;

ONCOLOGY;

BACTERIAL MAGNETIC PARTICLE; BIOTIN; MACROGOL; MELANOMA ANTIGEN 1; NANOPARTICLE; STREPTAVIDIN; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; ARTICLE; BIOTINYLATION; CANCER IMMUNOTHERAPY; CANCER PATIENT; CELL SEPARATION; CELL STIMULATION; CELL SURFACE; CONJUGATION; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DISPERSION; ENZYME SYNTHESIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MELANOMA; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN BINDING; PROTEIN MODIFICATION; VACCINATION;

BACTERIA (MICROORGANISMS);

EID: 62549143466     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc800398d     Document Type: Article

References (27)

1. Anderson, B., Park, B. J., Verdaguer, J., Amrani, A., and Santamaria, P. (1999) Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes. Proc. Natl. Acad. Sci. U.S.A. 96, 9311-9316.
2. Pinilla, C., Rubio-Godoy, V., Dutoit, V., Guillaume, P., Simon, R., Zhao, Y., Houghten, R. A., Cerottini, J. C., Romero, P., and Valmori, D. (2001) Combinatorial peptide libraries as an alternative approach to the identification of ligands for tumor-reactive cytolytic T lymphocytes. Cancer Res. 61, 5153 5160.
3. Hermentin, P., Doenges, R., Franssen, U., Bieva, C., Vander Brugghen, F. J., Stryckmans, P., Friesen, H. J., Optaczy, B., Schneider, S., Ax, W., et al. (1990) Hinge-thiol coupling of monoclonal antibody to silanized iron oxide particles and evaluation of magnetic cell depletion. Bioconjugate Chem. 1, 411-418.
4. Campbell, J. D., Piechaczek, C., Winkels, G., Schwamborn, E., Micheli, D., Hennemann, S., and Schmitz, J. (2005) Isolation and generation of clinical-grade dendritic cells using the Clini-MACS system. Methods Mol. Med. 109, 55-70.
5. Jing, Y., Moore, L. R., Williams, P. S., Chalmers, J. J., Farag, S. S., Bolwell, B., and Zborowski, M. (2007) Blood progenitor cell separation from clinical leukapheresis product by magnetic nanoparticle binding and magnetophoresis. Biotechnol. Bioeng. 96, 1139-1154.
6. Leyendeckers, H., Voth, E., Schicha, H., Hunzelmann, N., Banga, P., and Schmitz, J. (2002) Frequent detection of thyroid peroxidase-specific IgG+ memory B cells in blood of patients with autoimmune thyroid disease. Eur. J. Immunol. 32, 3126-3132.
7. Miltenyi, S., Muller, W., Weichel, W., and Radbruch, A. (1990) High gradient magnetic cell separation with MACS. Cytometry 11, 231-238.
8. Altman, J. D., Moss, P. A., Goulder, P. J., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J., and Davis, M. M. (1996) Phenotypic analysis of antigen-specific T lymphocytes. Science 274, 94-96.
9. Verginis, P., McLaughlin, K. A., Wucherpfennig, K. W., von Boehmer, H., and Apostolou, I. (2008) Induction of antigen-specific regulatory T cells in wild-type mice: visualization and largels of suppression. Proc. Natl. Acad. Sci. U.S.A. 105, 3479-3484.
10. Vonderheide, R. H., Domchek, S. M., Schultze, J. L., George, D. J., Hoar, K. M., Chen, D. Y., Stephans, K. F., Masutomi, K., Loda, M., Xia, Z., Anderson, K. S., Hahn, W. C., and Nadler, L. M. (2004) Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin. Cancer. Res. 10, 828-839.
11. Yoshino, T., Hirabe, H., Takahashi, M., Kuhara, M., Takeyama, H., and Matsunaga, T. (2008) Magnetic cell separation using nano-sized bacterial magnetic particles wilh reconsttucled magnetosome membrane. Biotechnol. Bioeng. 101, 470-477.
12. Kuhara, M., Takeyama, H., Tanaka, T., and Matsunaga, T. (2004) Magnetic cell separation using antibody binding with protein a expressed on bacterial magnetic particles. Anal. Chem. 76, 6207-6213.
13. Matsunaga, T., Takahashi, M., Yoshino, T., Kuhara, M., and Takeyama, H. (2006) Magnetic separation of CD14+ cells using antibody binding with protein A expressed on bacterial magnetic particles for generating dendritic cells. Biochem. Biophys. Res. Commun. 350, 1019-1025.
14. Takahashi, M., Yoshino, T., Takeyama, H., and Matsunaga, T. (2008) Direct magnetic separation of immune cells from whole blood using bacterial magnetic particles displaying protein G, Biotechnol. Prog., in press.
15. Matsunaga, T., Sakaguchi, T., and Tadokoro, F. (1991) Magnetite formation by a magnetic bacterium capable of growing aerobically. Appl. Microbiol. Biotechnol. 35, 651-655.
16. Tanaka, T., and Matsunaga, T. (2000) Fully automated chemiluminescence immunoassay of insulin using antibody-protein A-bacterial magnetic particle complexes. Anal. Chem. 72, 3518-3522.
17. Akiyama, Y., Kuzushima, K., Tsurumi, T., and Yamaguchi, K. (2004) Analysis of HLA-A24-restricted CMVpp65 peptide-specific CTL with HLA-A*2402-CMVpp65 tetramer. Immunol. Lett. 95, 199-205.
18. Schwidop, W. D., Klossek, P., Muller, R., and Claus, R. (1990) Procedure for the purification of streptavidin by hydrophobic interaction chromatography. J. Chromatogr. 520, 325-331.
19. Horak, D., Babic, M., Jendelova, P., Herynek, V., Trchova, M., Pientka, Z., Pollert, E., Hajek, M., and Sykova, E. (2007) D-Mannose-modified iron oxide nanoparticles for stem cell labeling. Bioconjugate Chem. 18, 635-644.
20. Hu, Y., Xie, J., Tong, Y. W., and Wang, C. H. (2007) Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells. J. Controlled Release 118, 7-17.
21. Lewin, M., Carlesso, N., Tung, C. H., Tang, X. W., Cory, D., Scadden, D. T., and Weissleder, R. (2000) Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. 18, 410-414.
22. Natarajan, A., Gruettner, C., Ivkov, R., DeNardo, G. L., Mirick, G., Yuan, A., Foreman, A., and DeNardo, S. J. (2008) NanoFerrite particle based radioimmunonanoparticles: binding affinity and in vivo pharmacokinetics. Bioconjugate Chem. 19, 1211-1218.
23. Sadzuka, Y., Nakade, A., Hirama, R., Miyagishima, A., Nozawa, Y., Hirota, S., and Sonobe, T. (2002) Effects of mixed polyethyleneglycol modification on fixed aqueous layer thickness and antitumor activity of doxorubicin containing liposome. Int. J. Pharm. 238, 171-180.
24. Appel, H., Kuon, W., Kuhne, M., Wu, P., Kuhlmann, S., Kollnberger, S., Thiel, A., Bowness, P., and Sieper, J. (2004) Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis. Arthritis Res. Ther. 6, R521-534.
25. Barnes, E., Ward, S. M., Kasprowicz, V. O., Dusheiko, G., Klenerman, P., and Lucas, M. (2004) Ultra-sensitive class I tetramer analysis reveals previously undetectable populations of antiviral CD8+ T cells. Eur. J. Immunol. 34, 1570-1577.
26. Kim, S. K., Devine, L., Angevine, M., DeMars, R., and Kavathas, P. B. (2000) Direct detection and magnetic isolation of Chlamydia trachomatis major outer membrane protein-specific CD8+ CTLs with HLA class I tetramers. J. Immunol. 165, 7285-7292.
27. McDermott, A. B., Spiegel, H. M., Irsch, J., Ogg, G. S., and Nixon, D. F. (2001) A simple and rapid magnetic bead separation technique for the isolation of tetramer-positive virus-specific CD8 T cells. Aids 15, 810-812.