Direct detection and magnetic isolation of Chlamydia trachomatis major outer membrane protein-specific CD8+ CTLs with HLA class I tetramers

Journal of Immunology

Volumn 165, Issue 12, 2000, Pages 7285-7292

  Kim, S K ^a   Devine, L ^a   Angevine, M ^a   DeMars, R ^a   Kavathas, P B ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; HLA A2 ANTIGEN; HLA ANTIGEN CLASS 1; OUTER MEMBRANE PROTEIN; TETRAMER;

ARTICLE; BACTERIAL MEMBRANE; BACTERIUM DETECTION; BACTERIUM ISOLATION; CELL SPECIFICITY; CELL STIMULATION; CHLAMYDIA TRACHOMATIS; CLINICAL ARTICLE; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENITAL TRACT INFECTION; HUMAN; MAGNETISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ISOLATION;

EID: 0034672107     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.12.7285     Document Type: Article

References (54)

1. Chlamydia trachomatis infections progress and problems
2. Trachoma
3. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure
4. Characterization of B-cell responses to Chlamydia trachomatis antigens in humans with trachoma
5. Antigen and isotype specificity of human B cell responses in immunopathogenesis of genital Chlamydia trachomatis infection
6. Persistence of chlamydial antibodies after pelvic inflammatory disease
7. Human serology in Chlamydia trachomatis infection with microimmunofluorescence
8. The role of immunoglobulin in the neutralization of trachoma infectivity
9. A peptide of Chlamydia trachomatis shown to be a primary T-cell epitope in vitro induces cell-mediated immunity in vivo
10. Synthetic peptides based on Chlamydia trachomatis antigens identify cytotoxic T lymphocyte responses in subjects from a trachoma-endemic population
11. Identification of T cells that respond to serovar-specific regions of the Chlamydia trachomatis major outer membrane protein in persons with serovar E infection
12. + CTLs specific for the major outer membrane protein of Chlamydia trachomatis in human genital tract infections
13. Chlamydia trachomatis major outer membrane protein (MOMP) epitopes that activate HLA class II-restricted T cells from infected humans
14. T-cell epitopes in variable segments of Chlamydia trachomatis major outer membrane protein elicit serovar-specific immune responses by infected humans
15. Cellular immune response during uncomplicated genital infection with Chlamydia trachomatis in humans
16. Lymphocyte proliferative responses to chlamydial antigens in human chlamydial eye infections
17. Antigen-specific proliferative human T-lymphocyte clones with specificity for Chlamydia trachomatis
18. Class II-HLA restriction of antigen-specific human T-lymphocyte clones
19. The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group
20. Experimental inclusion conjunctivitis in man
21. Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes
22. Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis
23. Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis
24. + T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract
25. Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection
26. + T cells in primary Chlamydia infection
27. Safe haven the cell biology of nonfusogenic pathogen vacuoles
28. The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments
29. Cell Biology
30. Phenotypic analysis of antigen-specific T lymphocytes
31. Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood
32. + T cells specific for EBV in healthy virus carriers
33. The minimum peptide epitope from the influenza virus matrix protein extra and intracellular loading of HLA-A2
34. Use of peptide libraries to map the substrate specificity of a peptide-modifying enzyme a 13 residue consensus peptide specifies biotinylation in Escherichia coli
35. HLA-A2-peptide complexes refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides
36. + T cells during the primary immune response to Epstein-Barr virus in vivo
37. Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization
38. Comparative analysis of cytotoxic T lymphocytes in lymph nodes and peripheral blood of simian immunodeficiency virus-infected rhesus monkeys
39. Chlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates
40. + T cell epitope from the vacuolar intracellular pathogen Chlamydia trachomatis
41. Immunological memory and protective immunity understanding their relation
42. + cytotoxic T lymphocytes for resistance to mucosal viral transmission in mice and enhancement of resistance by local administrations of IL-12
43. Long-term immunity and protection against herpes simplex virus type 2 in the murine female genital tract after mucosal but not systemic immunization
44. HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women
45. Molecular and mutation trends analyses of omp1 alleles for serovar E of Chlamydia trachomatis implications for the immunopathogenesis of disease
46. Human antibodies to linear B cell epitopes in variable sequence regions of the major outer membrane protein of Chlamydia trachomatis
47. Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph
48. 7 integrins in human intestinal mucosa and organized gut-associated lymphoid tissue
49. Differential homing commitments of antigen-specific T cells after oral or parenteral immunization in humans
50. + cells with memory for intestinal rotavirus
51. Homing of naive and memory T lymphocyte subsets to Peyer's patches, lymph nodes, and spleen
52. Mucosal phenotype of antiviral cytotoxic T lymphocytes in the vaginal mucosa of SIV-infected rhesus macaques
53. Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice