Discovery of novel triple helical DNA intercalators by an integrated virtual and actual screening platform

Nucleic Acids Research

Volumn 37, Issue 4, 2009, Pages 1280-1287

  Holt, Patrick A ^a   Ragazzon, Patricia ^a   Strekowski, Lucjan ^c   Chaires, Jonathan B ^a,b   Trent, John O ^a,b  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b University of Louisville School of Medicine   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERCALATING AGENT; NAPTHYLQUINOLINE MHQ 12; OLIGONUCLEOTIDE; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DENATURATION; DNA BINDING; DNA HELIX; LIGAND BINDING; MOLECULAR DOCKING; NUCLEIC ACID STRUCTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TRIPLE HELIX; VIRTUAL SCREENING;

CIRCULAR DICHROISM; DIALYSIS; DNA; DRUG DISCOVERY; INTERCALATING AGENTS; LIGANDS; NUCLEIC ACID DENATURATION; POLYDEOXYRIBONUCLEOTIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOFTWARE;

EID: 62549131251     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn1043     Document Type: Article

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