Lipid rafts uncouple surface expression of transmembrane TNF-α from its cytotoxicity associated with ICAM-1 clustering in Raji cells

Molecular Immunology

Volumn 46, Issue 7, 2009, Pages 1551-1560

  Zhang, Shu ^a   Liu, Tao ^a   Liang, Huifang ^a   Zhang, Hailong ^a   Yan, Dan ^a   Wang, Nidan ^a   Jiang, Xiaodan ^a   Feng, Wei ^a   Wang, Jing ^a   Li, Pinlan ^b   Li, Zhuoya ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytotoxicity; ICAM 1; Lipid rafts; Transmembrane TNF

Indexed keywords

ALANINE; CAVEOLIN 1; CYSTEINE; INTERCELLULAR ADHESION MOLECULE 1; METHYL BETA CYCLODEXTRIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL CONTACT; CELL SURFACE; CONTROLLED STUDY; CYTOTOXICITY; DISSOCIATION; HUMAN; HUMAN CELL; LIPID RAFT; MOLECULAR INTERACTION; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAJI CELL; SIGNAL TRANSDUCTION;

ANTIGENS, SURFACE; CELL ADHESION; CELL LINE, TUMOR; CELL MEMBRANE; CYTOTOXICITY, IMMUNOLOGIC; HELA CELLS; HUMANS; IMMUNITY, CELLULAR; INTERCELLULAR ADHESION MOLECULE-1; MEMBRANE MICRODOMAINS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; RECEPTORS, TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 62549129029     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.01.001     Document Type: Article

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