Comparison of the cytocidal effect induced by transmembrane and secreted TNF-alpha

Chinese Journal of Microbiology and Immunology

Volumn 18, Issue 1, 1998, Pages 499-504

  Shi, Wenfang ^a   Li, Zhuoya ^a   Gong, Feili ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Cytotoxicity; Tumor necrosis factor

Indexed keywords

EID: 0346964820     PISSN: 02545101     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Kriegler M, Perez C, Defay K, et al. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF. Cell, 1998, 53: 45-53.
2. Peck R, Brockhaus M, Rudolf F J, et al. The principal tumor necrosis factor receptor in monocyte cytotoxicity is on the effector cell, not on the target cell. Cell Immunol, 1991, 132: 308-318.
3. Chomczynski P, Sacchi N Single-step method RNA isolation by acid guanidinium thiocyangte-phenol-chloroform extraction. Anal Biochem, 1987, 162: 156-162.
4. Nichletli I, Migliorati G, Pagliaci MC, et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Method, 1991, 139: 271-279.
5. Dealtry GB, Naylor MS, Fiers W, et al. DNA fragmentation and cytotoxicity caused by tumor necrosis factor is enhanced by interferon-gamma. Eur J Immunol, 1987, 17: 689-695.
6. Laster SM, Wood JG and Gooding. Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J Immunol, 1988, 141: 2629-2634.
7. Grell M, Douni E, Wajant H, et al. The transmenbrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell, 1995, 83: 793-801.
8. Sampson LE, Mire Sluis A, Meager A. Protein kinase C-dependent phosphorylation is involved in resistance to tumour necrosis factor-α-induced cytotoxicity in a human monocytoid cell line, Biochem Journal, 1993, 292: 289-294.
9. Yoshimura T and Sone S. Different and synergistic actions of human tumor necrosis factor and interferon-gamma in damage of liposome membranes. J Biol Chem, 1987, 262: 4597-4603.
10. Kull FC and Cuatrecasas P. Possible requirement of internalization in the mechanism of in vitro cytotoxicity in tumor necrosis serum. Cancer Res, 1981, 41: 4885-4891.