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Volumn 6, Issue 1, 2009, Pages 84-89

Structure and activity of the internal ribosome entry site within the human p27Kip1 5′-untranslated region

Author keywords

5 UTR; Cell cycle; IRES; p27Kip1; RNA structure

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; HUR PROTEIN; MESSENGER RNA; NUCLEASE; NUCLEOTIDE;

EID: 62549122944     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.6.1.7572     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • Chu IM, Hengst L, Slingerland JM. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 2008; 8:253-67.
    • (2008) Nat Rev Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 2
    • 0041308069 scopus 로고    scopus 로고
    • Cell cycle-dependent translation of p27 involves a responsive element in its 5′-UTR that overlaps with a uORF
    • Gopfert U, Kullmann M, Hengst L. Cell cycle-dependent translation of p27 involves a responsive element in its 5′-UTR that overlaps with a uORF. Hum Mol Genet 2003; 12:1767-79.
    • (2003) Hum Mol Genet , vol.12 , pp. 1767-1779
    • Gopfert, U.1    Kullmann, M.2    Hengst, L.3
  • 3
    • 0029670477 scopus 로고    scopus 로고
    • Kip1 accumulation during the cell cycle
    • Kip1 accumulation during the cell cycle. Science 1996; 271:1861-4.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 5
    • 0037053407 scopus 로고    scopus 로고
    • Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status
    • Vidal A, Millard SS, Miller JP, Koff A. Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status. J Biol Chem 2002; 277:16433-40.
    • (2002) J Biol Chem , vol.277 , pp. 16433-16440
    • Vidal, A.1    Millard, S.S.2    Miller, J.P.3    Koff, A.4
  • 6
    • 15144357686 scopus 로고    scopus 로고
    • Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest
    • Millard SS, Yan JS, Nguyen H, Pagano M, Kiyokawa H, Koff A. Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J Biol Chem 1997; 272:7093-8.
    • (1997) J Biol Chem , vol.272 , pp. 7093-7098
    • Millard, S.S.1    Yan, J.S.2    Nguyen, H.3    Pagano, M.4    Kiyokawa, H.5    Koff, A.6
  • 7
    • 0034947868 scopus 로고    scopus 로고
    • Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation
    • Miskimins WK, Wang G, Hawkinson M, Miskimins R. Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation. Mol Cell Biol 2001; 21:4960-7.
    • (2001) Mol Cell Biol , vol.21 , pp. 4960-4967
    • Miskimins, W.K.1    Wang, G.2    Hawkinson, M.3    Miskimins, R.4
  • 8
    • 0036894711 scopus 로고    scopus 로고
    • Kullmann M, Gopfert U, Siewe B, Hengst L. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes Dev 2002; 16:3087-99.
    • Kullmann M, Gopfert U, Siewe B, Hengst L. ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes Dev 2002; 16:3087-99.
  • 9
    • 0033864096 scopus 로고    scopus 로고
    • A U-rich element in the 5′ untranslated region is necessary for the translation of p27 mRNA
    • Millard SS, Vidal A, Markus M, Koff A. A U-rich element in the 5′ untranslated region is necessary for the translation of p27 mRNA. Mol Cell Biol 2000; 20:5947-59.
    • (2000) Mol Cell Biol , vol.20 , pp. 5947-5959
    • Millard, S.S.1    Vidal, A.2    Markus, M.3    Koff, A.4
  • 11
    • 36248998866 scopus 로고    scopus 로고
    • Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation
    • Chaudhuri S, Vyas K, Kapasi P, Komar AA, Dinman JD, Barik S, Mazumder B. Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation. RNA 2007; 13:2224-37.
    • (2007) RNA , vol.13 , pp. 2224-2237
    • Chaudhuri, S.1    Vyas, K.2    Kapasi, P.3    Komar, A.A.4    Dinman, J.D.5    Barik, S.6    Mazumder, B.7
  • 15
    • 15744386891 scopus 로고    scopus 로고
    • Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway
    • Shi Y, Sharma A, Wu H, Lichtenstein A, Gera J. Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway. J Biol Chem 2005; 280:10964-73.
    • (2005) J Biol Chem , vol.280 , pp. 10964-10973
    • Shi, Y.1    Sharma, A.2    Wu, H.3    Lichtenstein, A.4    Gera, J.5
  • 17
    • 33646543044 scopus 로고    scopus 로고
    • Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita
    • Yoon A, Peng G, Brandenburger Y, Zollo O, Xu W, Rego E, Ruggero D. Impaired control of IRES-mediated translation in X-linked dyskeratosis congenita. Science 2006; 312:902-6.
    • (2006) Science , vol.312 , pp. 902-906
    • Yoon, A.1    Peng, G.2    Brandenburger, Y.3    Zollo, O.4    Xu, W.5    Rego, E.6    Ruggero, D.7
  • 20
    • 21244431682 scopus 로고    scopus 로고
    • Internal ribosome entry sites in cellular mRNAs: Mystery of their existence
    • Komar AA, Hatzoglou M. Internal ribosome entry sites in cellular mRNAs: mystery of their existence. J Biol Chem 2005; 280:23425-8.
    • (2005) J Biol Chem , vol.280 , pp. 23425-23428
    • Komar, A.A.1    Hatzoglou, M.2
  • 21
    • 2342633872 scopus 로고    scopus 로고
    • Cellular internal ribosome entry segments: Structures, trans-acting factors and regulation of gene expression
    • Stoneley M, Willis AE. Cellular internal ribosome entry segments: structures, trans-acting factors and regulation of gene expression. Oncogene 2004; 23:3200-7.
    • (2004) Oncogene , vol.23 , pp. 3200-3207
    • Stoneley, M.1    Willis, A.E.2
  • 24
    • 0037349339 scopus 로고    scopus 로고
    • The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr
    • Mitchell SA, Spriggs KA, Coldwell MJ, Jackson RJ, Willis AE. The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. Mol Cell 2003; 11:757-71.
    • (2003) Mol Cell , vol.11 , pp. 757-771
    • Mitchell, S.A.1    Spriggs, K.A.2    Coldwell, M.J.3    Jackson, R.J.4    Willis, A.E.5
  • 27
    • 4344604206 scopus 로고    scopus 로고
    • Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs
    • Martineau Y, Le Bec C, Monbrun L, Allo V, Chiu IM, Danos O, Moine H, Prats H, Prats AC. Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs. Mol Cell Biol 2004; 24:7622-35.
    • (2004) Mol Cell Biol , vol.24 , pp. 7622-7635
    • Martineau, Y.1    Le Bec, C.2    Monbrun, L.3    Allo, V.4    Chiu, I.M.5    Danos, O.6    Moine, H.7    Prats, H.8    Prats, A.C.9
  • 29
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res 2003; 31:3406-15.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 30
    • 0023665902 scopus 로고
    • An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res 1987; 15:8125-48.
    • (1987) Nucleic Acids Res , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 31
    • 55849133028 scopus 로고    scopus 로고
    • Stoppoloni D, Cardillo I, Verdina A, Vincenzi B, Menegozzo S, Santini M, Sacchi A, Baldi A, Galati R. Expression of the embryonic lethal abnormal vision-like protein HuR in human mesothelioma: association with cyclooxygenase-2 and prognosis. Cancer 2008.
    • Stoppoloni D, Cardillo I, Verdina A, Vincenzi B, Menegozzo S, Santini M, Sacchi A, Baldi A, Galati R. Expression of the embryonic lethal abnormal vision-like protein HuR in human mesothelioma: association with cyclooxygenase-2 and prognosis. Cancer 2008.
  • 35
    • 25144472553 scopus 로고    scopus 로고
    • Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma
    • Erkinheimo TL, Sivula A, Lassus H, Heinonen M, Furneaux H, Haglund C, Butzow R, Ristimaki A. Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma. Gynecol Oncol 2005; 99:14-9.
    • (2005) Gynecol Oncol , vol.99 , pp. 14-19
    • Erkinheimo, T.L.1    Sivula, A.2    Lassus, H.3    Heinonen, M.4    Furneaux, H.5    Haglund, C.6    Butzow, R.7    Ristimaki, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.