Synthesis, physicochemical properties, and evaluation of N-substituted- 2-alkyl-3-hydroxy-4(1H)-pyridinones

Journal of Medicinal Chemistry

Volumn 41, Issue 18, 1998, Pages 3347-3359

  Rai, Bijaya L ^a   Dekhordi, Lotfollah S ^a   Khodr, Hicham ^a   Jin, Yi ^a   Liu, Zudong ^a   Hider, Robert C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYL 1 (2' HYDROXYETHYL) 3 HYDROXYPYRIDIN 4 ONE; DEFERIPRONE; IRON COMPLEX; LIGAND; PYRIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; IRON CHELATION; IRON KINETICS; IRON OVERLOAD; LIGAND BINDING; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PKA; RAT; THALASSEMIA;

ANIMALS; BILE; FERRITINS; IRON; IRON CHELATING AGENTS; MALE; MOLECULAR CONFORMATION; PYRIDONES; RATS; RATS, INBRED F344; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032572829     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9707784     Document Type: Article

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