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Volumn 48, Issue 3, 2009, Pages 272-284

Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BISULFITE; CPG OLIGODEOXYNUCLEOTIDE; DNA METHYLTRANSFERASE INHIBITOR; GENOMIC DNA; PROTEIN KINASE FES;

EID: 62449123072     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20638     Document Type: Article
Times cited : (17)

References (44)
  • 3
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer-A mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. 2006. Epigenetic gene silencing in cancer-A mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6:107-116.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 4
    • 0025975985 scopus 로고
    • DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
    • Boyes J, Bird A. 1991. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 64:1123-1134.
    • (1991) Cell , vol.64 , pp. 1123-1134
    • Boyes, J.1    Bird, A.2
  • 5
    • 0033506708 scopus 로고    scopus 로고
    • Regulation of c-Fes tyrosine kinase and biological activities by N-ter-minal coiled-coil oligomerization domains
    • Cheng HY, Rogers JA, Dunham NA, Smithgall TE. 1999. Regulation of c-Fes tyrosine kinase and biological activities by N-ter-minal coiled-coil oligomerization domains. Mol Cell Biol 19:8335-8343.
    • (1999) Mol Cell Biol , vol.19 , pp. 8335-8343
    • Cheng, H.Y.1    Rogers, J.A.2    Dunham, N.A.3    Smithgall, T.E.4
  • 6
    • 0035724447 scopus 로고    scopus 로고
    • A point mutation in the N-terminal coiled-coil domain releases c-Fes tyrosine ki-nase activity and survival signaling in myeloid leukemia cells
    • Cheng HY, Schiavone AP, Smithgall TE. 2001. A point mutation in the N-terminal coiled-coil domain releases c-Fes tyrosine ki-nase activity and survival signaling in myeloid leukemia cells. Mol Cell Biol 21:6170-6180.
    • (2001) Mol Cell Biol , vol.21 , pp. 6170-6180
    • Cheng, H.Y.1    Schiavone, A.P.2    Smithgall, T.E.3
  • 7
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy
    • Christman JK. 2002. 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy. Oncogene 21:5483-5495.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 8
    • 0030977310 scopus 로고    scopus 로고
    • A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins
    • Cross SH, Meehan RR, Nan X, Bird A. 1997. A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins. Nat Genet 16:256-259.
    • (1997) Nat Genet , vol.16 , pp. 256-259
    • Cross, S.H.1    Meehan, R.R.2    Nan, X.3    Bird, A.4
  • 9
    • 33749389961 scopus 로고    scopus 로고
    • The KRAB-associ-ated co-repressor KAP-1 is a coiled-coil binding partner, substrate, and activator of the c-Fes protein-tyrosine kinase
    • Delfino FJ, Shaffer JM, Smithgall TE. 2006a. The KRAB-associ-ated co-repressor KAP-1 is a coiled-coil binding partner, substrate, and activator of the c-Fes protein-tyrosine kinase. Biochem J 399:141-150.
    • (2006) Biochem J , vol.399 , pp. 141-150
    • Delfino, F.J.1    Shaffer, J.M.2    Smithgall, T.E.3
  • 10
    • 33646830138 scopus 로고    scopus 로고
    • A growth-sup-pressive function for the c-Fes protein-tyrosine kinase in colorectal cancer
    • Delfino FJ, Stevenson HM, Smithgall TE. 2006b. A growth-sup-pressive function for the c-Fes protein-tyrosine kinase in colorectal cancer. J Biol Chem 281:8829-8835.
    • (2006) J Biol Chem , vol.281 , pp. 8829-8835
    • Delfino, F.J.1    Stevenson, H.M.2    Smithgall, T.E.3
  • 11
    • 0141606726 scopus 로고    scopus 로고
    • Effects of DNA methylation on expression of tumor suppressor genes and proto-onco-gene in human colon cancer cell lines
    • Fang JY, Lu J, Chen YX, Yang L. 2003. Effects of DNA methylation on expression of tumor suppressor genes and proto-onco-gene in human colon cancer cell lines. World J Gastroenterol 9:1976-1980.
    • (2003) World J Gastroenterol , vol.9 , pp. 1976-1980
    • Fang, J.Y.1    Lu, J.2    Chen, Y.X.3    Yang, L.4
  • 12
    • 0024439569 scopus 로고
    • A highly efficient retroviral vector allows detection of the transforming activity of the human c-fpslfes proto-oncogene
    • Feldman RA, Lowy DR, Vass WC, Velu TJ. 1989. A highly efficient retroviral vector allows detection of the transforming activity of the human c-fpslfes proto-oncogene. J Virol 63:5469-5474.
    • (1989) J Virol , vol.63 , pp. 5469-5474
    • Feldman, R.A.1    Lowy, D.R.2    Vass, W.C.3    Velu, T.J.4
  • 13
    • 0036273766 scopus 로고    scopus 로고
    • Closing in on the biological functions of Fps/Fes and Fer
    • Greer PA. 2002. Closing in on the biological functions of Fps/Fes and Fer. Nat Rev Mol Cell Biol 3:278-289.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 278-289
    • Greer, P.A.1
  • 14
    • 0023832116 scopus 로고
    • The human c-fpslfes gene product expressed ectopically in rat fibroblasts is nontransforming and has restrained protein-tyrosine kinase activity
    • Greer PA, Meckling-Hansen K, Pawson T. 1988. The human c-fpslfes gene product expressed ectopically in rat fibroblasts is nontransforming and has restrained protein-tyrosine kinase activity. Mol Cell Biol 8:578-587.
    • (1988) Mol Cell Biol , vol.8 , pp. 578-587
    • Greer, P.A.1    Meckling-Hansen, K.2    Pawson, T.3
  • 15
    • 0028095405 scopus 로고
    • The Fps/Fes protein-tyrosine kinase promotes angiogene-sis in transgenic mice
    • Greer P, Haigh J, Mbamalu G, Khoo W, Bernstein A, Pawson T. 1994. The Fps/Fes protein-tyrosine kinase promotes angiogene-sis in transgenic mice. Mol Cell Biol 14:6755-6763.
    • (1994) Mol Cell Biol , vol.14 , pp. 6755-6763
    • Greer, P.1    Haigh, J.2    Mbamalu, G.3    Khoo, W.4    Bernstein, A.5    Pawson, T.6
  • 16
    • 0029804948 scopus 로고    scopus 로고
    • The Fps/Fes tyrosine kinase is expressed in myeloid, vascular endothelial, epithelial and neuronal cells and is localized to the trans-golgi network
    • Haigh J, McVeigh J, Greer P. 1996. The Fps/Fes tyrosine kinase is expressed in myeloid, vascular endothelial, epithelial and neuronal cells and is localized to the trans-golgi network. Cell Growth Differentiation 7:931-944.
    • (1996) Cell Growth Differentiation , vol.7 , pp. 931-944
    • Haigh, J.1    McVeigh, J.2    Greer, P.3
  • 17
    • 0024121584 scopus 로고
    • Cytosine methylation does not affect binding of transcription factor Sp1
    • Harrington MA, Jones PA, Imagawa M, Karin M. 1988. Cytosine methylation does not affect binding of transcription factor Sp1. Proc Natl Acad Sci USA 85:2066-2070.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2066-2070
    • Harrington, M.A.1    Jones, P.A.2    Imagawa, M.3    Karin, M.4
  • 19
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, Sidransky D, Baylin SB. 1995. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55:4525-4530.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 20
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB. 2003. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349:2042-2054.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 21
    • 0029883719 scopus 로고    scopus 로고
    • The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU1, and a novel transcription factor
    • Heydemann A, Juang G, Hennessy K, Parmacek MS, Simon MC. 1996. The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU1, and a novel transcription factor. Mol Cell Biol 16:1676-1686.
    • (1996) Mol Cell Biol , vol.16 , pp. 1676-1686
    • Heydemann, A.1    Juang, G.2    Hennessy, K.3    Parmacek, M.S.4    Simon, M.C.5
  • 22
    • 0030664221 scopus 로고    scopus 로고
    • Expression of two myeloid cell-specific genes requires the novel transcription factor, c-fes expression factor
    • Heydemann A, Boehmler JH, Simon MC. 1997. Expression of two myeloid cell-specific genes requires the novel transcription factor, c-fes expression factor. J Biol Chem 272:29527-29537.
    • (1997) J Biol Chem , vol.272 , pp. 29527-29537
    • Heydemann, A.1    Boehmler, J.H.2    Simon, M.C.3
  • 23
    • 0024083068 scopus 로고
    • Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated
    • Holler M, Westin G, Jiricny J, Schaffner W. 1988. Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev 2:1127-1135.
    • (1988) Genes Dev , vol.2 , pp. 1127-1135
    • Holler, M.1    Westin, G.2    Jiricny, J.3    Schaffner, W.4
  • 24
    • 0033928171 scopus 로고    scopus 로고
    • The epigenetics of colorectal cancer
    • Issa JP. 2000. The epigenetics of colorectal cancer. Ann NY Acad Sci 910:140-153.
    • (2000) Ann NY Acad Sci , vol.910 , pp. 140-153
    • Issa, J.P.1
  • 25
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. 2002. The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415-428.
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 26
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones PA, Takai D. 2001. The role of DNA methylation in mammalian epigenetics. Science 293:1068-1070.
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 27
    • 0842278570 scopus 로고    scopus 로고
    • Epigenetic changes in colorectal cancer
    • Kondo Y, Issa JP. 2004. Epigenetic changes in colorectal cancer. Cancer Metastisis Rev 23:29-39.
    • (2004) Cancer Metastisis Rev , vol.23 , pp. 29-39
    • Kondo, Y.1    Issa, J.P.2
  • 28
    • 0026747761 scopus 로고
    • Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P, Klein F, Bird A. 1992. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69:905-914.
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1    Meehan, R.R.2    Henzel, W.J.3    Maurer-Fogy, I.4    Jeppesen, P.5    Klein, F.6    Bird, A.7
  • 29
    • 0034652454 scopus 로고    scopus 로고
    • The c-Fes protein-tyrosine kinase suppresses cytokine-independent outgrowth of myeloid leukemia cells induced by Bcr-Abl
    • Lionberger JM, Smithgall TE. 2000. The c-Fes protein-tyrosine kinase suppresses cytokine-independent outgrowth of myeloid leukemia cells induced by Bcr-Abl. Cancer Res 60:1097-1103.
    • (2000) Cancer Res , vol.60 , pp. 1097-1103
    • Lionberger, J.M.1    Smithgall, T.E.2
  • 31
    • 0024342686 scopus 로고
    • Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
    • Meehan RR, Lewis JD, McKay S, Kleiner EL, Bird AP. 1989.Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs. Cell 58:499-507.
    • (1989) Cell , vol.58 , pp. 499-507
    • Meehan, R.R.1    Lewis, J.D.2    McKay, S.3    Kleiner, E.L.4    Bird, A.P.5
  • 33
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • Nan X, Campoy FJ, Bird A. 1997. MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88:471-481.
    • (1997) Cell , vol.88 , pp. 471-481
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 34
    • 0033960560 scopus 로고    scopus 로고
    • Single-site methylation within the p53 promoter region reduces gene expression in a reporter gene construct: Possible in vivo relevance during tumorigenesis
    • Pogribny IP, Pogribna M, Christman JK, James SJ. 2000. Single-site methylation within the p53 promoter region reduces gene expression in a reporter gene construct: possible in vivo relevance during tumorigenesis. Cancer Res 60:588-594.
    • (2000) Cancer Res , vol.60 , pp. 588-594
    • Pogribny, I.P.1    Pogribna, M.2    Christman, J.K.3    James, S.J.4
  • 35
    • 0029125443 scopus 로고
    • DNA binding specificities of Spi-1/PU1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter
    • Ray-Gallet D, Mao C, Tavitian A, Moreau-Gachelin F. 1995. DNA binding specificities of Spi-1/PU1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter. Oncogene 11:303-313.
    • (1995) Oncogene , vol.11 , pp. 303-313
    • Ray-Gallet, D.1    Mao, C.2    Tavitian, A.3    Moreau-Gachelin, F.4
  • 36
    • 0034201441 scopus 로고    scopus 로고
    • EMBOSS: The European Molecular Biology Open Software Suite
    • Rice P, Longden I, Bleasby A. 2000. EMBOSS: The European Molecular Biology Open Software Suite. Trends Genet 16:276-277.
    • (2000) Trends Genet , vol.16 , pp. 276-277
    • Rice, P.1    Longden, I.2    Bleasby, A.3
  • 37
    • 0031771497 scopus 로고    scopus 로고
    • The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53
    • Robertson KD, Jones PA. 1998. The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Mol Cell Biol 18:6457-6473.
    • (1998) Mol Cell Biol , vol.18 , pp. 6457-6473
    • Robertson, K.D.1    Jones, P.A.2
  • 38
    • 0033727448 scopus 로고    scopus 로고
    • Src homology 2 domain substitution modulates the kinase and transforming activities of the Fes protein-tyrosine kinase
    • Rogers JA, Cheng HY, Smithgall TE. 2000. Src homology 2 domain substitution modulates the kinase and transforming activities of the Fes protein-tyrosine kinase. Cell Growth Differ 11:581-592.
    • (2000) Cell Growth Differ , vol.11 , pp. 581-592
    • Rogers, J.A.1    Cheng, H.Y.2    Smithgall, T.E.3
  • 40
    • 0026412583 scopus 로고
    • Elevated expression of the c-fes proto-oncogene in adult human myeloid leukemia cells in the absence of gene amplification
    • Smithgall TE, Johnston JB, Bustin M, Glazer RI. 1991. Elevated expression of the c-fes proto-oncogene in adult human myeloid leukemia cells in the absence of gene amplification. J Natl Cancer Inst 83:42-46.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 42-46
    • Smithgall, T.E.1    Johnston, J.B.2    Bustin, M.3    Glazer, R.I.4
  • 41
    • 0023723108 scopus 로고
    • Identification of the differentiation-associated p93 tyrosine protein kinase of HL-60 leukemia cells as the product of the human c-fes locus and its expression in myelomonocytic cells
    • Smithgall TE, Yu G, Glazer RI. 1988. Identification of the differentiation-associated p93 tyrosine protein kinase of HL-60 leukemia cells as the product of the human c-fes locus and its expression in myelomonocytic cells. J Biol Chem 263:15050-15055.
    • (1988) J Biol Chem , vol.263 , pp. 15050-15055
    • Smithgall, T.E.1    Yu, G.2    Glazer, R.I.3
  • 43
    • 14644396228 scopus 로고    scopus 로고
    • Detection and interpretation of altered methyl-ation patterns in cancer cells
    • Ushijima T. 2005. Detection and interpretation of altered methyl-ation patterns in cancer cells. Nat Rev Cancer 5:223-231.
    • (2005) Nat Rev Cancer , vol.5 , pp. 223-231
    • Ushijima, T.1
  • 44
    • 0024356203 scopus 로고
    • K562 leukemia cells trans-fected with the human c-fes gene acquire the ability to undergo myeloid differentiation
    • Yu G, Smithgall TE, Glazer RI. 1989. K562 leukemia cells trans-fected with the human c-fes gene acquire the ability to undergo myeloid differentiation. J Biol Chem 264:10276-10281.
    • (1989) J Biol Chem , vol.264 , pp. 10276-10281
    • Yu, G.1    Smithgall, T.E.2    Glazer, R.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.