Synthesis of 1-deoxy-l-gulonojirimycin and 1-deoxy-l-talonojirimycin

Tetrahedron Letters

Volumn 50, Issue 18, 2009, Pages 2045-2047

  Guaragna, Annalisa ^a   D'Alonzo, Daniele ^a   Paolella, Concetta ^a   Palumbo, Giovanni ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Dihydroxylation; Glycosidase inhibitors; l Iminosugars; Polyhydroxylated piperidines

Indexed keywords

1 DEOXY GULONOJIRIMYCIN; 1 DEOXY TALONOJIRIMYCIN; ALDEHYDE; GLYCOSIDASE INHIBITOR; IMINOSUGAR; PIPERIDINE; UNCLASSIFIED DRUG;

ARTICLE; DIHYDROXYLATION; DRUG SYNTHESIS;

GULO;

EID: 62349097770     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.02.111     Document Type: Article

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26. 4: C, 44.16; H, 8.03; N, 8.58. Found: C, 43.89; H, 7.87; N, 8.70.
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28. 4: C, 44.16; H, 8.03; N, 8.58. Found: C, 44.45; H, 8.10; N, 8.39.
29. 3OD) δ 1.47 (s, 4.5H), 1.48 (s, 4.5H), 3.47-3.60 (m, 1H), 3.51 (br t, J = 10.8 Hz, 1H), 3.81 (br dd, J = 11.2, 3.3 Hz, 1H), 4.09-4.12 (m, 0.5H), 4.15-4.18 (m, 0.5H), 4.40 (br s, 1H), 4.54 (br s, 1H), 5.63 (br d, J = 10.2 Hz, 1H), 5.64-5.75 (m, 1H).