Effect of cold storage on in vitro human skin absorption of six 14C-radiolabeled environmental contaminants: Benzo[a]pyrene, ethylene glycol, methyl parathion, naphthalene, nonyl phenol, and toluene

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 72, Issue 8, 2009, Pages 505-517

  Moody, Richard P ^a   Yip, Anna ^a   Chu, Ih ^a  

^a HEALTH CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; BENZO[A]PYRENE; BOVINE SERUM ALBUMIN; CARBON 14; ETHYLENE GLYCOL; NAPHTHALENE; NONYLPHENOL; PARATHION METHYL; TOLUENE;

ARTICLE; BREAST; CONTROLLED STUDY; CRYOPRESERVATION; DIFFUSION; FEMALE; HUMAN; HUMAN TISSUE; ISOTOPE LABELING; LIPOPHILICITY; LOW TEMPERATURE; PERFUSION; PRIORITY JOURNAL; SKIN ABSORPTION; STORAGE TEMPERATURE; TISSUE PRESERVATION;

BENZO(A)PYRENE; COLD TEMPERATURE; ENVIRONMENTAL POLLUTANTS; ETHYLENE GLYCOL; FEMALE; HUMANS; METHYL PARATHION; NAPHTHALENES; PHENOLS; SKIN; SKIN ABSORPTION; TISSUE PRESERVATION; TOLUENE; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

BOVINAE;

EID: 62249222621     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390802328713     Document Type: Article

References (47)

1. Babu, R. J., Kanikkannan, N., Kikwai, L., Ortega, C., Andega, S., Ball, K., Yim, S., and Singh, M. 2003. The influence of various methods of cold storage of skin on the permeation of melatonin and nimesulide. J. Controlled Release 86:49-57.
2. Baxter, C., Aggarwal, S., and Diller, K. R. 1985. Cryopreservation of skin: A review. Transplant. Proc. 17(Suppl. 4):112-120.
3. Ben-Bassat, H., Chaouat, M., Segal, N., Zumai, E., Wexler, M. R., and Eldad, A. 2001. How long can cryopreserved skin be stored to maintain adequate graft performance? Burns 27:425-431.
4. Bosman, I. J., Ensing, K., and de Zeeuw, R. A. 1998. Standardization procedure for the in vitro skin permeation of anticholinergics. Int. J. Pharm. 169: 65-73.
5. Bronaugh, R. L., Stewart, R. F., and Simon, M. 1986. Methods for in vitro percutaneous absorption studies. VII: Use of excised human skin. J. Pharm. Sci. 75:1094-1097.
6. Chu, I. 1995. Alternative methods to animal testing: A Canadian Health Protection Branch perspective. ATLA 23:257-261.
7. Collier, S. W., Sheikh, N. M., Sakr, A., Lichtin, J. L., Stewart, R. F., and Bronaugh, R. L. 1989. Maintenance of skin viability during in vitro percutaneous absorption/metabolism studies. Toxicol. Appl. Pharmacol. 99:522-533.
8. Dayan, N. 2005. Pathways for skin penetration. Cosmet. Toiletries 120:67-74.
9. Feldmann, R. J., and Maibach, H. I. 1970. Absorption of some organic compounds through the skin in man. J. Invest. Dermatol. 54:399-404.
10. Feldmann, R. J., and Maibach, H. I. 1974. Percutaneous penetration of some pesticides and herbicides in man. Toxicol. Appl. Pharmacol. 28:126-132.
11. Franklin, C. A., Somers, D. A., and Chu, I. 1989. Use of percutaneous absorption data in risk assessment. J. Am. Coll. Toxicol. 8:815-827.
12. Hadzija, B. W., Ruddy, S. B., and Ballenger, E. S. 1992. Effect of freezing on iontophoretic transport through hairless rat skin. J. Pharm. Pharmacol. 44:387-390.
13. Harrison, S. M., Barry, B. W., and Dugard, P. H. 1984. Effects of freezing on human skin permeability. J. Pharm. Pharmacol. 36:261-262.
14. Hawkins, G. S., Jr., and Reifenrath, W. G. 1984. Development of an in vitro model for determining the fate of chemicals applied to skin. Fundam. Appl. Toxicol. 4:S133-S144.
15. Hoang, K. T. 1992. Dermal exposure assessment: Principles and applications. U.S. Environmental Protection Agency, Exposure Assessment Group. Washington, DC: Office of Health and Environmental Assessment. Accessed January 23, 2008, at http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=12188.
16. Holland, J. M., Kao, J. Y., and Whitaker, M. J. 1984. A multisample apparatus for kinetic evaluation of skin penetration in vitro: The influence of viability and metabolic status of the skin. Toxicol. Appl. Pharmacol. 72:272-280.
17. Kasting G. B., and Bowman, L. A. 1990. Electrical analysis of fresh, excised human skin: A comparison with frozen skin. Pharm. Res. 7:1141-1146.
18. Kemppainen, B. W., Riley, R. T., Pace, J. G., and Hoerr, F. J. 1986. Effects of skin storage conditions and concentration of applied dose on [3H]T-2 toxin penetration through excised human and monkey skin. Food Chem. Toxicol. 24:221-227.
19. Kwah, M. 2001. In vitro viability assays. In Toxicology of skin, Target Organ Toxicology Series, ed. H. I. Maibach, pp. 513-529., Boca Raton, FL: Taylor & Francis.
20. May, S. R., and deClement, F. A. 1981. Skin banking. Part III. Cadaveric allograft skin viability. J. Burn Care Rehab. 2:128-141.
21. Menon, G. K., and Elias, P. M. 1997. Morphologic basis for a pore-pathway in mammalian stratum corneum. Skin Pharmacol. 10:235-246.
22. Mikhailov, I. N. 1976. Changes in the ultrastructure on the human epidermis on freezing. Bull. Exp. Biol. Med. 81:379-461.
23. Moir, D., Marwood, T. M., and Moody R. P. 1994. In vitro cutaneous metabolism of DDT in human and animal skins. Bull. Environ. Contam. Toxicol. 52:474-478.
24. Moody, R. P., Akram, M., Dickson, E., and Chu, I. 2007a. In vitro dermal absorption of methyl salicylate, ethyl parathion, and malathion: First responder safety. J. Toxicol. Environ. Health A 70:985-999.
25. Moody, R. P., Joncas, J., Richardson, M., and Chu, I. 2007b. Contaminated soils (I): In vitro dermal absorption of benzo[a]pyrene in human skin. J. Toxicol. Environ. Health A 70:1858-1865.
26. Moody, R. P., and MacPherson, H. 2003. Determination of dermal absorption QSAR/QSPRs by brute force regression: Multiparameter model development with Molsuite 2000. J. Toxicol Environ Health A 66:1927-1942.
27. 14C-labelled N,N-diethyl-m-toluamide through human skin and effects of short-wave ultraviolet radiation on permeation. Toxicol. In Vitro 4:193-199.
28. Nakai, J. S., Chu, I., Li-Muller, A., and Aucoin, R. 1997. Effect of environmental conditions on the penetration of benzene through human skin. J. Toxicol. Environ. Health A 51:447-462.
29. Nakai, J. S., Stathopulos, P. B., Campbell, G. L., Chu, I., Li-Muller, A., and Aucoin, R. 1999. Penetration of chloroform, trichloroethylene, and tetrachloroethylene through human skin. J. Toxicol. Environ. Health A 58:157-170.
30. Ng, K. M. E., Chu, I., Bronaugh, R. L., Franklin, C. A., and Somers, D. A. 1992. Percutaneous absorption and metabolism of pyrene, benzo[a]pyrene, and di(2-ethylhexyl) phthalate: Comparison of in vitro and in vivo results in the hairless guinea pig. Toxicol. Appl. Pharmacol. 115: 216-223.
31. Organization for Economic Cooperation and Cultural Development. 2000. Draft guidance document for the conduct of skin absorption studies. Environmental Health and Safety Publications, Environment Directorate series on testing and assessment No. 28. Paris: Organization for Economic Cooperation and Cultural Development.
32. Organization for Economic Cooperation and Cultural Development. 2004. Guideline for the testing of chemicals. Skin absorption: in vitro method 428. Paris: Organization for Economic Cooperation and Development.
33. Reifenrath, W. G., and Kemppainen, B. W. 1991. Skin storage conditons. In In vitro percutaneous absorption: Principles, fundamentals, and applications, eds. R. L. Bronaugh and H. I. Maibach, pp. 115-127. Boca Raton, FL: Taylor & Francis.
34. Rosenquist, M. D., Cram, A. E., and Kealey, G. P. 1988a. Short-term skin preservation at 4 degrees C: Skin storage configuration and tissue-tovolume medium ratio. J. Burn Care Rehab. 9:52-54.
35. Rosenquist, M. D., Cram, A. E., and Kealey, G. P. 1988b. Skin preservation at 4 degrees C: A species comparison. Cryobiology 25:31-37.
36. Ryan, J. 2006. General guide for cryogenically storing animal cell cultures. Technical bulletin. Corning Life Sciences. Sigma Cell Culture Manual 2005-2006, pp. 327-331. Accessed January 14, 2008, at www.corning. com/Lifesciences/technical-information/techDocs/t-cryoanimalcc.pdf.
37. Sintov, A. C., and Botner, S. 2006. Transdermal drug delivery using microencapsulation and aqueous systems: Influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems. Int. J. Pharma. 311:55-62.
38. Shaikh, N. A., Ademola, J. I., and Maibach, H. I. 1996. Effects of freezing and azide treatment of in vitro human skin on the flux and metabolism of 8-methoxypsoralen. Skin Pharmacol. 9:274-280.
39. Schuhmaker-Wolz, U., Kalberlah, F., Oppl, R., and Van Hemmen, J. J. 2003. A toolkit for dermal risk assessment: Toxicological approach for hazard characterization. Ann. Occup. Hyg. 47:641-652.
40. Swarbrick, J., Lee, G., and Brown, J. 1982. Drug permeation through human skin: I. Effect of storage conditions of skin. J. Invest. Dermatol. 78:63-66.
41. Tezel A., Sens A., and Mitragotri, S. 2002. Incorporation of lipophilic pathways into the porous pathway model for describing skin permeabilization during low-frequency sonophoresis. J. Control. Release 83:183-188.
42. Tezel, A., Sens, A., and Mitragotri, S. 2003. Description of transdermal transport of hydrophilic solutes during low-frequency sonophoresis based on a modified porous pathway model. J. Pharm. Sci. 92:381-393.
43. U.S. Environmental Protection Agency. 1997. Dermal route. In Exposure factors handbook revised, Vol, 1 General factors, Chapter 6. Washington, DC: U.S. Environmental Protection Agency, National Center for Environmental Assessment. Accessed January 23, 2008, at www.epa.gov/ncea/efh
44. Wang, T. F., Kasting, G. B., and Nitschei, J. M. 2007. Multiphase microscopic diffusion model for stratum corneum permeability. II. Estimation of physicochemical parameters, and application to a large permeability database. J. Pharm. Sci. 96:3024-3051.
45. Wester, R. C., Christoffel, J., Hartway, T., Poblete, N., Maibach, H. I., and Forsell, J. 1998. Human cadaver skin viability for in vitro percutaneous absorption: Storage and detrimental effects of heat-separation and freezing. Pharm. Res. 15:82-84.
46. Yourick, J. J., Koenig, M. L., Yourick, D. L., and Bronaugh, R. L. 2004. Fate of chemicals in skin after dermal application: Does the in vitro skin reservoir affect the estimate of systemic absorption? Toxicol. Appl. Pharmacol. 195:309-320.
47. Zieger, M. A. J., Tredget, E. E., Sykes, B. D., and McGann, L. E. 1997. Injury and protection in split-thickness skin after very rapid cooling and warming. Cryobiology 35: 53-69.