A multiphase microscopic diffusion model for stratum corneum permeability. II. Estimation of physicochemical parameters, and application to a large permeability database

Journal of Pharmaceutical Sciences

Volumn 96, Issue 11, 2007, Pages 3024-3051

  Wang, Tsuo Feng ^a,c   Kasting, Gerald B ^b   Nitsche, Johannes M ^a  

^a State University of New York ^*  (United States)

^b UNIVERSITY OF CINCINNATI ACADEMIC HEALTH CENTER   (United States)

^c National Science Council   (Taiwan)

Author keywords

Corneocyte; Diffusion coefficient; Intercellular lipid; Microstructure; Partition coefficient; Permeability; Stratum corneum (SC)

Indexed keywords

NICOTINAMIDE; TESTOSTERONE; WATER;

AQUEOUS SOLUTION; ARTICLE; CELL COMMUNICATION; CELL STRUCTURE; CELL SWELLING; DIFFUSION COEFFICIENT; DRUG DIFFUSION; DRUG PENETRATION; ELECTRON SPIN RESONANCE; HYDRATION; HYDRODYNAMICS; LIPOPHILICITY; MATHEMATICAL MODEL; MOLECULAR SIZE; MOLECULAR WEIGHT; PARTITION COEFFICIENT; PH MEASUREMENT; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; SKIN CELL; SKIN PERMEABILITY; SKIN SURFACE; STEADY STATE; STRATUM CORNEUM;

EID: 36849008672     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20883     Document Type: Article

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