Quantification of peramivir (a novel anti-influenza drug) in human plasma by hydrophilic interaction chromatography/tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 10, 2009, Pages 933-938

  Li, Ying ^a   Zhang, Xinzhong ^a   Wang, Xiaoying ^a   Li, Song ^a   Ruan, Jinxiu ^a   Zhang, Zhenqing ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Avian influenza; Hydrophilic interaction chromatography (HILIC); Neuraminidase inhibitor; Peramivir; Tandem mass spectrometry; TSK gel Amide 80 column

Indexed keywords

ACETONITRILE; AMIDES; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; DRUG INTERACTIONS; GELATION; GELS; HYDROPHILICITY; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC ACIDS; PLASMA (HUMAN); PLASMAS; SPECTRUM ANALYSIS;

AVIAN INFLUENZA; HYDROPHILIC INTERACTION CHROMATOGRAPHY (HILIC); NEURAMINIDASE INHIBITOR; PERAMIVIR; TANDEM MASS SPECTROMETRY; TSK GEL AMIDE-80 COLUMN;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID; ACETONITRILE; AMIDE; FORMIC ACID; PERAMIVIR; WATER;

ACCURACY; ARTICLE; ASSAY; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG STABILITY; HUMAN; HUMAN TISSUE; HYDROPHILIC INTERACTION CHROMATOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

ANTIVIRAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOPENTANES; GUANIDINES; HUMANS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

AVES;

EID: 62249219754     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.02.044     Document Type: Article

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