Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry

Journal of Separation Science

Volumn 31, Issue 9, 2008, Pages 1628-1633

  Ji, Hye Young ^a   Park, Eun Jeong ^a   Lee, Kang Choon ^b   Lee, Hye Suk ^a  

^a Wonkwang University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Doxazosin; HILIC MS; Human plasma; MS

Indexed keywords

AMMONIUM COMPOUNDS; CHEMICALS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ESTERS; FLOW INTERACTIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS; QUANTUM CHEMISTRY; SILICA; SILICATE MINERALS; SILICON COMPOUNDS; STANDARDS;

ALKALINE PH; AMMONIUM FORMATE; ANALYTES; APPLIED (CO); ATLANTIS; CISAPRIDE; CONCENTRATION RANGES; DOXAZOSIN; ESI MS MS; ETHYL ACETATE (ETAC); HILIC-MS/MS; HUMAN PLASMAS; HYDROPHILIC INTERACTION CHROMATOGRAPHY (HILIC); HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY (HILIC); HYDROPHILIC INTERACTIONS; INTERNAL STANDARD (IS); MATRIX EFFECTS; MOBILE PHASE; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; RELATIVE ERROR (RE); SELECTIVE METHOD; SILICA COLUMNS; TANDEM MASS SPECTROMETRY (MS/MS);

LIQUID CHROMATOGRAPHY;

CISAPRIDE; DOXAZOSIN;

AREA UNDER THE CURVE; ARTICLE; CHROMATOGRAPHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; HUMAN; HUMAN EXPERIMENT; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PHASE SEPARATION; PRIORITY JOURNAL; QUANTITATIVE STUDY; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

CHROMATOGRAPHY, LIQUID; CISAPRIDE; DOXAZOSIN; HUMANS; QUALITY CONTROL; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 45949105364     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200700662     Document Type: Article

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