Improvement of the high-speed log D assay using an injection marker for the water plug aspiration/injection method

Journal of Chromatography A

Volumn 1216, Issue 15, 2009, Pages 2984-2988

  Nishimura, Ikuko ^a   Hirano, Atsushi ^a   Yamashita, Taro ^a   Fukami, Takehiro ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

High speed log D; Injection marker; Lipophilicity; Log D measurements

Indexed keywords

AUTOMATED SAMPLINGS; HIGH-SPEED LOG D; IMPROVED METHODS; INJECTION MARKER; LIPOPHILICITY; LOG D MEASUREMENTS; MANUAL INSPECTIONS; WATER PHASE;

SPEED;

WATER INJECTION;

2 (4 METHOXYPHENOXY) 4,8 DIMETHYLQUINOLINE; 3 (4 CHLOROPHENYL) 2 PHENOXYQUINOLINE; ALPRENOLOL; BIFONAZOLE; CARBAMAZEPINE; CHLORPROMAZINE; CHLORPROTHIXENE; CLOTRIMAZOLE; DESIPRAMINE; DEXAMETHASONE; DILTIAZEM; FLUFENAMIC ACID; LIDOCAINE; METOPROLOL; NIFEDIPINE; NIFLUMIC ACID; OCTANOL; PHENAZONE; PROPRANOLOL; QUINOLINE DERIVATIVE; TOLNAFTATE; UNCLASSIFIED DRUG;

ARTICLE; ASPIRATION; AUTOMATION; CHEMICAL ANALYSIS; DRUG DETERMINATION; PRIORITY JOURNAL; SAMPLING; SCREENING;

ALGORITHMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; HYDROPHOBICITY; LIPIDS; MASS SPECTROMETRY; OCTANOLS; QUINOLINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLUBILITY; WATER;

EID: 62249181516     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.02.004     Document Type: Article

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