Direct analysis of valsartan or candesartan in human plasma and urines by on-line solid phase extraction coupled to electrospray tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 10, 2009, Pages 919-926

  Levi, Mikaël ^a,b   Wuerzner, Grégoire ^c,d,e   Ezan, Eric ^a   Pruvost, Alain ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b SPI BIO   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e INSERM   (France)

Author keywords

Candesartan; High throughput; Mass spectrometry; On line solid phase extraction; Valsartan

Indexed keywords

ACCURACY AND PRECISION; ASSAY METHODS; AT1 RECEPTORS; CANDESARTAN; DIRECT ANALYSIS; ELECTROSPRAY TANDEM MASS SPECTROMETRIES; HIGH THROUGHPUT; HUMAN PLASMAS; NUMBER OF SAMPLES; ON-LINE SOLID PHASE EXTRACTION; RUN-TIME; TANDEM MASS SPECTROMETRIES; VALSARTAN;

BODY FLUIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS; SPECTRUM ANALYSIS; THROUGHPUT;

EXTRACTION;

CANDESARTAN; CANDESARTAN HEXETIL; VALSARTAN;

ACCURACY; ARTICLE; ASSAY; DRUG BLOOD LEVEL; DRUG URINE LEVEL; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

BENZIMIDAZOLES; HUMANS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TETRAZOLES; VALINE;

EID: 62249174362     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.02.030     Document Type: Article

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