메뉴 건너뛰기




Volumn 20, Issue 4, 2009, Pages 461-474

Changes in connective tissue in patients with pelvic organ prolapse - A review of the current literature

Author keywords

Connective tissue; Extracellular matrix; Fibroblast; Pelvic floor; Prolapse

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 5; ELASTIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FIBULIN 5; GELATINASE B; MATRIX METALLOPROTEINASE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PENTOSIDINE;

EID: 62249160005     PISSN: 09373462     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00192-008-0737-1     Document Type: Review
Times cited : (197)

References (99)
  • 1
    • 0031743326 scopus 로고    scopus 로고
    • Epidemiology and natural history of pelvic floor dysfunction
    • Bump RC, Norton PA (1998) Epidemiology and natural history of pelvic floor dysfunction. Obstet Gynecol Clin North Am 25:723-746
    • (1998) Obstet Gynecol Clin North Am , vol.25 , pp. 723-746
    • Bump, R.C.1    Norton, P.A.2
  • 4
    • 0036205362 scopus 로고    scopus 로고
    • Pelvic organ prolapse and connective tissue abnormalities in Korean women
    • Bai SW, Choe BH, Kim JY, Park KH (2002) Pelvic organ prolapse and connective tissue abnormalities in Korean women. J Reprod Med 47:231-234
    • (2002) J Reprod Med , vol.47 , pp. 231-234
    • Bai, S.W.1    Choe, B.H.2    Kim, J.Y.3    Park, K.H.4
  • 5
    • 0030989578 scopus 로고    scopus 로고
    • Epidemiology of genital prolapse: Observations from the Oxford Family Planning Association Study
    • Mant J, Painter R, Vessey M (1997) Epidemiology of genital prolapse: observations from the Oxford Family Planning Association Study. Br J Obstet Gynaecol 104:579-585
    • (1997) Br J Obstet Gynaecol , vol.104 , pp. 579-585
    • Mant, J.1    Painter, R.2    Vessey, M.3
  • 7
    • 33846384326 scopus 로고    scopus 로고
    • Sequence variant in the laminin gamma 1 (LAMC1) gene associated with familial pelvic organ prolapse
    • Nikolova G, Lee H, Berkovitz S, Nelson S, Sinsheimer J, Vilain E et al (2007) Sequence variant in the laminin gamma 1 (LAMC1) gene associated with familial pelvic organ prolapse. Human Genetics 120:847-856
    • (2007) Human Genetics , vol.120 , pp. 847-856
    • Nikolova, G.1    Lee, H.2    Berkovitz, S.3    Nelson, S.4    Sinsheimer, J.5    Vilain, E.6
  • 8
    • 34648858638 scopus 로고    scopus 로고
    • Familial transmission of urogenital prolapse and incontinence
    • Twiss C, Triaca V, Rodriguez LV (2007) Familial transmission of urogenital prolapse and incontinence. Curr Opin Obstet Gynecol 19:464-468
    • (2007) Curr Opin Obstet Gynecol , vol.19 , pp. 464-468
    • Twiss, C.1    Triaca, V.2    Rodriguez, L.V.3
  • 12
    • 16644362978 scopus 로고    scopus 로고
    • Stem cell therapy for urinary incontinence and pelvic floor disorders: A novel approach
    • Bhatia NN, Ho MH (2004) Stem cell therapy for urinary incontinence and pelvic floor disorders: A novel approach. Curr Opin Obstet Gynecol 16:397-398
    • (2004) Curr Opin Obstet Gynecol , vol.16 , pp. 397-398
    • Bhatia, N.N.1    Ho, M.H.2
  • 14
    • 0026682792 scopus 로고
    • Anatomic aspects of vaginal eversion after hysterectomy
    • Delancey JO (1992) Anatomic aspects of vaginal eversion after hysterectomy. Am J Obstet Gynecol 166:1717-1724
    • (1992) Am J Obstet Gynecol , vol.166 , pp. 1717-1724
    • Delancey, J.O.1
  • 15
    • 0037391231 scopus 로고    scopus 로고
    • Pelvic connective tissue resilience decreases with vaginal delivery, menopause and uterine prolapse
    • Reay Jones NH, Healy JC, King LJ, Saini S, Shousha S, Len-Mersh TG (2003) Pelvic connective tissue resilience decreases with vaginal delivery, menopause and uterine prolapse. Br J Surg 90:466-472
    • (2003) Br J Surg , vol.90 , pp. 466-472
    • Reay Jones, N.H.1    Healy, J.C.2    King, L.J.3    Saini, S.4    Shousha, S.5    Len-Mersh, T.G.6
  • 16
    • 0142247232 scopus 로고    scopus 로고
    • Biomechanical and biochemical assessments for pelvic organ prolapse
    • Goh JT (2003) Biomechanical and biochemical assessments for pelvic organ prolapse. Curr Opin Obstet Gynecol 15:391-394
    • (2003) Curr Opin Obstet Gynecol , vol.15 , pp. 391-394
    • Goh, J.T.1
  • 17
    • 0000523565 scopus 로고
    • Structure of collagen
    • Ramachandran G, Kartha G (1955) Structure of collagen. Nature 176:593-395
    • (1955) Nature , vol.176 , pp. 395-593
    • Ramachandran, G.1    Kartha, G.2
  • 18
    • 0035978878 scopus 로고    scopus 로고
    • Molecular mechanisms of ageing in connective tissues
    • Bailey AJ (2001) Molecular mechanisms of ageing in connective tissues. Mech Ageing Dev 122:735-755
    • (2001) Mech Ageing Dev , vol.122 , pp. 735-755
    • Bailey, A.J.1
  • 19
    • 0025870239 scopus 로고
    • Synthesis of collagen types I and III in reincised wounds in humans
    • Haukipuro K (1991) Synthesis of collagen types I and III in reincised wounds in humans. Br J Surg 78:708-712
    • (1991) Br J Surg , vol.78 , pp. 708-712
    • Haukipuro, K.1
  • 20
    • 0020663639 scopus 로고
    • Alterations in collagen production in mixed mononuclear leukocyte-fibroblast cultures
    • Hibbs MS, Postlethwaite AE, Mainardi CL, Seyer JM, Kang AH (1983) Alterations in collagen production in mixed mononuclear leukocyte-fibroblast cultures. J Exp Med 157:47-59
    • (1983) J Exp Med , vol.157 , pp. 47-59
    • Hibbs, M.S.1    Postlethwaite, A.E.2    Mainardi, C.L.3    Seyer, J.M.4    Kang, A.H.5
  • 21
    • 0035219340 scopus 로고    scopus 로고
    • Type V collagen: Heterotypic type I/V collagen interactions in the regulation of fibril assembly
    • Birk DE (2001) Type V collagen: Heterotypic type I/V collagen interactions in the regulation of fibril assembly. Micron 32:223-237
    • (2001) Micron , vol.32 , pp. 223-237
    • Birk, D.E.1
  • 22
    • 0025343595 scopus 로고
    • Collagen fibrillogenesis in vitro: Interaction of types I and V collagen regulates fibril diameter
    • Birk DE, Fitch JM, Babiarz JP, Doane KJ, Linsenmayer TF (1990) Collagen fibrillogenesis in vitro: Interaction of types I and V collagen regulates fibril diameter. J Cell Sci 95:649-657
    • (1990) J Cell Sci , vol.95 , pp. 649-657
    • Birk, D.E.1    Fitch, J.M.2    Babiarz, J.P.3    Doane, K.J.4    Linsenmayer, T.F.5
  • 23
    • 14644397265 scopus 로고    scopus 로고
    • Pelvic Organ Support Study (POSST): The distribution, clinical definition, and epidemiologic condition of pelvic organ support defects
    • Swift S, Woodman P, O'Boyle A, Kahn M, Valley M, Bland D et al (2005) Pelvic Organ Support Study (POSST): The distribution, clinical definition, and epidemiologic condition of pelvic organ support defects. Am J Obstet Gynecol 192:795-806
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 795-806
    • Swift, S.1    Woodman, P.2    O'Boyle, A.3    Kahn, M.4    Valley, M.5    Bland, D.6
  • 24
    • 0032401898 scopus 로고    scopus 로고
    • Mechanisms of maturation and ageing of collagen
    • Bailey AJ, Paul RG, Knott L (1998) Mechanisms of maturation and ageing of collagen. Mech Ageing Dev 106:1-56
    • (1998) Mech Ageing Dev , vol.106 , pp. 1-56
    • Bailey, A.J.1    Paul, R.G.2    Knott, L.3
  • 25
    • 0030477949 scopus 로고    scopus 로고
    • Glycation of collagen: The basis of its central role in the late complications of ageing and diabetes
    • Paul RG, Bailey AJ (1996) Glycation of collagen: The basis of its central role in the late complications of ageing and diabetes. Int J Biochem Cell Biol 28:1297-1310
    • (1996) Int J Biochem Cell Biol , vol.28 , pp. 1297-1310
    • Paul, R.G.1    Bailey, A.J.2
  • 26
    • 4444304939 scopus 로고    scopus 로고
    • Regulation of matrix biology by matrix metalloproteinases
    • Mott JD, Werb Z (2004) Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol 16:558-564
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 558-564
    • Mott, J.D.1    Werb, Z.2
  • 27
    • 0041352075 scopus 로고    scopus 로고
    • The matrix metalloproteinase system: Changes, regulation, and impact throughout the ovarian and uterine reproductive cycle
    • Curry TE Jr, Osteen KG (2003) The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle. Endocr Rev 24:428-465
    • (2003) Endocr Rev , vol.24 , pp. 428-465
    • Curry Jr., T.E.1    Osteen, K.G.2
  • 28
    • 0038675051 scopus 로고    scopus 로고
    • Differences in estrogen modulation of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-1 expression in cultured fibroblasts from continent and incontinent women
    • Chen B, Wen Y, Wang H, Polan ML (2003) Differences in estrogen modulation of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-1 expression in cultured fibroblasts from continent and incontinent women. Am J Obstet Gynecol 189:59-65
    • (2003) Am J Obstet Gynecol , vol.189 , pp. 59-65
    • Chen, B.1    Wen, Y.2    Wang, H.3    Polan, M.L.4
  • 29
    • 0030717692 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
    • Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP (1997) Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions. Eur J Cell Biol 74:111-22
    • (1997) Eur J Cell Biol , vol.74 , pp. 111-122
    • Gomez, D.E.1    Alonso, D.F.2    Yoshiji, H.3    Thorgeirsson, U.P.4
  • 30
    • 20644467063 scopus 로고    scopus 로고
    • Estrogen increases collagen I and III mRNA expression in the pelvic support tissues of the rhesus macaque
    • Clark AL, Slayden OD, Hettrich K, Brenner RM (2005) Estrogen increases collagen I and III mRNA expression in the pelvic support tissues of the rhesus macaque. Am J Obstet Gynecol 192:1523-1529
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 1523-1529
    • Clark, A.L.1    Slayden, O.D.2    Hettrich, K.3    Brenner, R.M.4
  • 31
    • 0031759613 scopus 로고    scopus 로고
    • Hydroxyapatite induces autolytic degradation and inactivation of matrix metalloproteinase-1 and -3
    • Kremer EA, Chen Y, Suzuki K, Nagase H, Gorski JP (1998) Hydroxyapatite induces autolytic degradation and inactivation of matrix metalloproteinase-1 and -3. J Bone Miner Res 13:1890-1902
    • (1998) J Bone Miner Res , vol.13 , pp. 1890-1902
    • Kremer, E.A.1    Chen, Y.2    Suzuki, K.3    Nagase, H.4    Gorski, J.P.5
  • 32
    • 0348012918 scopus 로고    scopus 로고
    • Aspartic acid racemization: Evidence for marked longevity of elastin in human skin
    • Ritz-Timme S, Laumeier I, Collins MJ (2003) Aspartic acid racemization: evidence for marked longevity of elastin in human skin. Br J Dermatol 149:951-959
    • (2003) Br J Dermatol , vol.149 , pp. 951-959
    • Ritz-Timme, S.1    Laumeier, I.2    Collins, M.J.3
  • 33
    • 33144484432 scopus 로고    scopus 로고
    • Failure of elastic fiber homeostasis leads to pelvic floor disorders
    • Liu X, Zhao Y, Pawlyk B, Damaser M, Li T (2006) Failure of elastic fiber homeostasis leads to pelvic floor disorders. Am J Pathol 168:519-528
    • (2006) Am J Pathol , vol.168 , pp. 519-528
    • Liu, X.1    Zhao, Y.2    Pawlyk, B.3    Damaser, M.4    Li, T.5
  • 34
    • 44649084286 scopus 로고    scopus 로고
    • LOXL1 deficiency negatively impacts the biomechanical properties of the mouse vagina and supportive tissues
    • Alperin M, Debes K, Abramowitch S, Meyn L, Moalli PA (2008) LOXL1 deficiency negatively impacts the biomechanical properties of the mouse vagina and supportive tissues. Int Urogynecol J Pelvic Floor Dysfunct 19:977-986
    • (2008) Int Urogynecol J Pelvic Floor Dysfunct , vol.19 , pp. 977-986
    • Alperin, M.1    Debes, K.2    Abramowitch, S.3    Meyn, L.4    Moalli, P.A.5
  • 36
    • 33947501362 scopus 로고    scopus 로고
    • Pelvic organ prolapse in fibulin-5 knockout mice: Pregnancy-induced changes in elastic fiber homeostasis in mouse vagina
    • Drewes PG, Yanagisawa H, Starcher B, Hornstra I, Csiszar K, Marinis SI et al (2007) Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Am J Pathol 170:578-589
    • (2007) Am J Pathol , vol.170 , pp. 578-589
    • Drewes, P.G.1    Yanagisawa, H.2    Starcher, B.3    Hornstra, I.4    Csiszar, K.5    Marinis, S.I.6
  • 37
    • 0034267605 scopus 로고    scopus 로고
    • Effects of food restriction or delayed photostimulation on ovarian follicle number, plasma oestradiol concentration and vaginal collagen content in male-line turkeys
    • Buchanan S, Robertson GW, Hocking PM (2000) Effects of food restriction or delayed photostimulation on ovarian follicle number, plasma oestradiol concentration and vaginal collagen content in male-line turkeys. Br Poult Sci 41:502-507
    • (2000) Br Poult Sci , vol.41 , pp. 502-507
    • Buchanan, S.1    Robertson, G.W.2    Hocking, P.M.3
  • 39
    • 0347357752 scopus 로고    scopus 로고
    • Collagen content of nonsupport tissue in pelvic organ prolapse and stress urinary incontinence
    • Wong MY, Harmanli OH, Agar M, Dandolu V, Grody MH (2003) Collagen content of nonsupport tissue in pelvic organ prolapse and stress urinary incontinence. Am J Obstet Gynecol 189:1597-1599
    • (2003) Am J Obstet Gynecol , vol.189 , pp. 1597-1599
    • Wong, M.Y.1    Harmanli, O.H.2    Agar, M.3    Dandolu, V.4    Grody, M.H.5
  • 42
    • 0142134108 scopus 로고    scopus 로고
    • Changes in extracellular matrix proteins in the cardinal ligaments of post-menopausal women with or without prolapse: A computerized immunohistomorphometric analysis
    • Ewies AA, Al-Azzawi F, Thompson J (2003) Changes in extracellular matrix proteins in the cardinal ligaments of post-menopausal women with or without prolapse: A computerized immunohistomorphometric analysis. Hum Reprod 18:2189-2195
    • (2003) Hum Reprod , vol.18 , pp. 2189-2195
    • Ewies, A.A.1    Al-Azzawi, F.2    Thompson, J.3
  • 43
  • 44
    • 0032730185 scopus 로고    scopus 로고
    • Regulation of extracellular matrix gene expression by mechanical stress
    • Chiquet M (1999) Regulation of extracellular matrix gene expression by mechanical stress. Matrix Biol 18:417-426
    • (1999) Matrix Biol , vol.18 , pp. 417-426
    • Chiquet, M.1
  • 47
    • 0036271444 scopus 로고    scopus 로고
    • Collagen metabolism and turnover in women with stress urinary incontinence and pelvic prolapse
    • Chen BH, Wen Y, Li H, Polan ML (2002) Collagen metabolism and turnover in women with stress urinary incontinence and pelvic prolapse. Int Urogynecol J Pelvic Floor Dysfunct 13:80-87
    • (2002) Int Urogynecol J Pelvic Floor Dysfunct , vol.13 , pp. 80-87
    • Chen, B.H.1    Wen, Y.2    Li, H.3    Polan, M.L.4
  • 48
    • 33748252069 scopus 로고    scopus 로고
    • Remodeling of vaginal connective tissue in patients with prolapse
    • Alperin M, Moalli PA (2006) Remodeling of vaginal connective tissue in patients with prolapse. Curr Opin Obstet Gynecol 18:544-550
    • (2006) Curr Opin Obstet Gynecol , vol.18 , pp. 544-550
    • Alperin, M.1    Moalli, P.A.2
  • 49
    • 33947705625 scopus 로고    scopus 로고
    • Regulation of MMP-1 by sex steroid hormones in fibroblasts derived from the female pelvic floor
    • Zong W, Zyczynski HM, Meyn LA, Gordy SC, Moalli PA (2007) Regulation of MMP-1 by sex steroid hormones in fibroblasts derived from the female pelvic floor. Am J Obstet Gynecol 196:349-311
    • (2007) Am J Obstet Gynecol , vol.196 , pp. 311-349
    • Zong, W.1    Zyczynski, H.M.2    Meyn, L.A.3    Gordy, S.C.4    Moalli, P.A.5
  • 50
    • 33644804403 scopus 로고    scopus 로고
    • Collagen metabolism in the uterosacral ligaments and vaginal skin of women with uterine prolapse
    • Phillips CH, Anthony F, Benyon C, Monga AK (2006) Collagen metabolism in the uterosacral ligaments and vaginal skin of women with uterine prolapse. Br J Obstet Gynaec 113:39-46
    • (2006) Br J Obstet Gynaec , vol.113 , pp. 39-46
    • Phillips, C.H.1    Anthony, F.2    Benyon, C.3    Monga, A.K.4
  • 51
    • 28244441145 scopus 로고    scopus 로고
    • Marfan's syndrome
    • Judge DP, Dietz HC (2005) Marfan's syndrome. Lancet 366:1965-1976
    • (2005) Lancet , vol.366 , pp. 1965-1976
    • Judge, D.P.1    Dietz, H.C.2
  • 52
    • 0034089434 scopus 로고    scopus 로고
    • Urinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers Danlos syndrome
    • Carley ME, Schaffer J (2000) Urinary incontinence and pelvic organ prolapse in women with Marfan or Ehlers Danlos syndrome. Am J Obstet Gynecol 182:1021-1023
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 1021-1023
    • Carley, M.E.1    Schaffer, J.2
  • 53
    • 34447135704 scopus 로고    scopus 로고
    • Elastin expression and elastic fibre width in the anterior vaginal wall of postmenopausal women with and without prolapse
    • Karam JA, Vazquez DV, Lin VK, Zimmern PE (2007) Elastin expression and elastic fibre width in the anterior vaginal wall of postmenopausal women with and without prolapse. BJU Int 100:346-350
    • (2007) BJU Int , vol.100 , pp. 346-350
    • Karam, J.A.1    Vazquez, D.V.2    Lin, V.K.3    Zimmern, P.E.4
  • 54
    • 0017388541 scopus 로고
    • Determination of the elastin content of tissues by measuring desmosine and isodesmosine
    • Starcher BC (1977) Determination of the elastin content of tissues by measuring desmosine and isodesmosine. Anal Biochem 79:11-15
    • (1977) Anal Biochem , vol.79 , pp. 11-15
    • Starcher, B.C.1
  • 55
    • 1542333614 scopus 로고    scopus 로고
    • Elastolytic activity in women with stress urinary incontinence and pelvic organ prolapse
    • Chen B, Wen Y, Polan ML (2004) Elastolytic activity in women with stress urinary incontinence and pelvic organ prolapse. Neurourol Urodyn 23:119-126
    • (2004) Neurourol Urodyn , vol.23 , pp. 119-126
    • Chen, B.1    Wen, Y.2    Polan, M.L.3
  • 56
    • 43049179553 scopus 로고    scopus 로고
    • Differential elastin and tenascin immunolabeling in the uterosacral ligaments in postmenopausal women with and without pelvic organ prolapse
    • Goepel C (2007) Differential elastin and tenascin immunolabeling in the uterosacral ligaments in postmenopausal women with and without pelvic organ prolapse. Acta Histochem 110:204-209
    • (2007) Acta Histochem , vol.110 , pp. 204-209
    • Goepel, C.1
  • 57
    • 0031227466 scopus 로고    scopus 로고
    • Decrease in elastin gene expression and protein synthesis in fibroblasts derived from cardinal ligaments of patients with prolapsus uteri
    • Yamamoto K, Yamamoto M, Akazawa K, Tajima S, Wakimoto H, Aoyagi M (1997) Decrease in elastin gene expression and protein synthesis in fibroblasts derived from cardinal ligaments of patients with prolapsus uteri. Cell Biol Int 21:605-611
    • (1997) Cell Biol Int , vol.21 , pp. 605-611
    • Yamamoto, K.1    Yamamoto, M.2    Akazawa, K.3    Tajima, S.4    Wakimoto, H.5    Aoyagi, M.6
  • 58
    • 0036916319 scopus 로고    scopus 로고
    • Histopathological evaluation of the connective tissue of the vaginal fascia and the uterine ligaments in women with and without pelvic relaxation
    • Kokcu A, Yanik F, Cetinkaya M, Alper T, Kandemir B, Malatyalioglu E (2002) Histopathological evaluation of the connective tissue of the vaginal fascia and the uterine ligaments in women with and without pelvic relaxation. Arch Gynecol Obstet 266:75-78
    • (2002) Arch Gynecol Obstet , vol.266 , pp. 75-78
    • Kokcu, A.1    Yanik, F.2    Cetinkaya, M.3    Alper, T.4    Kandemir, B.5    Malatyalioglu, E.6
  • 59
    • 0022466261 scopus 로고
    • Histological changes in the vaginal connective tissue of patients with and without uterine prolapse
    • Makinen J, Soderstrom KO, Kiilholma P, Hirvonen T (1986) Histological changes in the vaginal connective tissue of patients with and without uterine prolapse. Arch Gynecol 239:17-20
    • (1986) Arch Gynecol , vol.239 , pp. 17-20
    • Makinen, J.1    Soderstrom, K.O.2    Kiilholma, P.3    Hirvonen, T.4
  • 60
    • 13444310991 scopus 로고    scopus 로고
    • The expression and function of the endothelin system in contractile properties of vaginal myofibroblasts of women with uterovaginal prolapse
    • Poncet S, Meyer S, Richard C, Aubert JD, Juillerat-Jeanneret L (2005) The expression and function of the endothelin system in contractile properties of vaginal myofibroblasts of women with uterovaginal prolapse. Am J Obstet Gynecol 192:426-432
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 426-432
    • Poncet, S.1    Meyer, S.2    Richard, C.3    Aubert, J.D.4    Juillerat-Jeanneret, L.5
  • 62
    • 40049103909 scopus 로고    scopus 로고
    • Changes in transcription profile and cytoskeleton morphology in pelvic ligament fibroblasts in response to stretch - The effects of oestradiol and levormeloxifene
    • Ewies AA, El-Shafie M, Li J, Stanley A, Thompson J, Styles JA et al (2008) Changes in transcription profile and cytoskeleton morphology in pelvic ligament fibroblasts in response to stretch - the effects of oestradiol and levormeloxifene. Mol Hum Reprod 14:127-135
    • (2008) Mol Hum Reprod , vol.14 , pp. 127-135
    • Ewies, A.A.1    El-Shafie, M.2    Li, J.3    Stanley, A.4    Thompson, J.5    Styles, J.A.6
  • 63
    • 0031986776 scopus 로고    scopus 로고
    • Decrease in p53 protein in cultured cardinal ligament fibroblasts from patients with prolapsus uteri
    • Yamamoto M, Aoyagi M, Akazawa K, Tajima S, Yamamoto K (1998) Decrease in p53 protein in cultured cardinal ligament fibroblasts from patients with prolapsus uteri. Cell Biol Int 22:31-40
    • (1998) Cell Biol Int , vol.22 , pp. 31-40
    • Yamamoto, M.1    Aoyagi, M.2    Akazawa, K.3    Tajima, S.4    Yamamoto, K.5
  • 64
    • 0033923014 scopus 로고    scopus 로고
    • Changes in biological characteristics during the cellular aging of ligament fibroblasts derived from patients with prolapsus uteri
    • Yamamoto M, Akazawa K, Aoyagi M, Yamamoto K (2000) Changes in biological characteristics during the cellular aging of ligament fibroblasts derived from patients with prolapsus uteri. Mech Ageing Dev 115:175-187
    • (2000) Mech Ageing Dev , vol.115 , pp. 175-187
    • Yamamoto, M.1    Akazawa, K.2    Aoyagi, M.3    Yamamoto, K.4
  • 65
    • 27744523363 scopus 로고    scopus 로고
    • Roles of estrogen receptor, progesterone receptor, p53 and p21 in pathogenesis of pelvic organ prolapse
    • Bai SW, Chung DJ, Yoon JM, Shin JS, Kim SK, Park KH (2005) Roles of estrogen receptor, progesterone receptor, p53 and p21 in pathogenesis of pelvic organ prolapse. Int Urogynecol J 16:492-496
    • (2005) Int Urogynecol J , vol.16 , pp. 492-496
    • Bai, S.W.1    Chung, D.J.2    Yoon, J.M.3    Shin, J.S.4    Kim, S.K.5    Park, K.H.6
  • 67
    • 0027499648 scopus 로고
    • Type III collagen content in the skin of postmenopausal women receiving oestradiol and testosterone implants
    • Savvas M, Bishop J, Laurent G, Watson N, Studd J (1993) Type III collagen content in the skin of postmenopausal women receiving oestradiol and testosterone implants. Br J Obstet Gynaecol 100:154-156
    • (1993) Br J Obstet Gynaecol , vol.100 , pp. 154-156
    • Savvas, M.1    Bishop, J.2    Laurent, G.3    Watson, N.4    Studd, J.5
  • 68
    • 0023136843 scopus 로고
    • Decline in skin collagen content and metacarpal index after the menopause and its prevention with sex hormone replacement
    • Brincat M, Moniz CF, Kabalan S, Versi E, O'Dowd T, Magos AL et al (1987) Decline in skin collagen content and metacarpal index after the menopause and its prevention with sex hormone replacement. Br J Obstet Gynaecol 94:126-129
    • (1987) Br J Obstet Gynaecol , vol.94 , pp. 126-129
    • Brincat, M.1    Moniz, C.F.2    Kabalan, S.3    Versi, E.4    O'Dowd, T.5    Magos, A.L.6
  • 69
    • 0023520996 scopus 로고
    • A study of the decrease of skin collagen content, skin thickness, and bone mass in the postmenopausal woman
    • Brincat M, Kabalan S, Studd JW, Moniz CF, de Trafford J, Montgomery J (1987) A study of the decrease of skin collagen content, skin thickness, and bone mass in the postmenopausal woman. Obstet Gynecol 70:840-845
    • (1987) Obstet Gynecol , vol.70 , pp. 840-845
    • Brincat, M.1    Kabalan, S.2    Studd, J.W.3    Moniz, C.F.4    de Trafford, J.5    Montgomery, J.6
  • 70
    • 33748282945 scopus 로고    scopus 로고
    • Roles of sex steroid receptors and cell cycle regulation in pathogenesis of pelvic organ prolapse
    • Da Chung J, Bai SW (2006) Roles of sex steroid receptors and cell cycle regulation in pathogenesis of pelvic organ prolapse. Curr Opin Obstet Gynecol 18:551-554
    • (2006) Curr Opin Obstet Gynecol , vol.18 , pp. 551-554
    • Da Chung, J.1    Bai, S.W.2
  • 71
    • 0037225414 scopus 로고    scopus 로고
    • Estrogen levels and estrogen receptors in patients with stress urinary incontinence and pelvic organ prolapse
    • Lang JH, Zhu L, Sun ZJ, Chen J (2003) Estrogen levels and estrogen receptors in patients with stress urinary incontinence and pelvic organ prolapse. Int J Gynaecol Obstet 80:35-39
    • (2003) Int J Gynaecol Obstet , vol.80 , pp. 35-39
    • Lang, J.H.1    Zhu, L.2    Sun, Z.J.3    Chen, J.4
  • 72
    • 3242877222 scopus 로고    scopus 로고
    • Changes in gonadal steroid receptors in the cardinal ligaments of prolapsed uteri: Immunohistomorphometric data
    • Ewies AA, Thompson J, Al Azzawi F (2004) Changes in gonadal steroid receptors in the cardinal ligaments of prolapsed uteri: immunohistomorphometric data. Hum Reprod 19:1622-1628
    • (2004) Hum Reprod , vol.19 , pp. 1622-1628
    • Ewies, A.A.1    Thompson, J.2    Al Azzawi, F.3
  • 74
    • 40549132219 scopus 로고    scopus 로고
    • Combined estrogen and ghrelin administration restores number of blood vessels and collagen type I/III ratio in the urethral and anal canal submucosa of old ovariectomized rats
    • Rizk DE, Hassan HA, Al Marzouqi AH, Ramadan GA, Al Kedrah SS, Daoud SA et al (2008) Combined estrogen and ghrelin administration restores number of blood vessels and collagen type I/III ratio in the urethral and anal canal submucosa of old ovariectomized rats. Int Urogynecol J Pelvic Floor Dysfunct 19:547-552
    • (2008) Int Urogynecol J Pelvic Floor Dysfunct , vol.19 , pp. 547-552
    • Rizk, D.E.1    Hassan, H.A.2    Al Marzouqi, A.H.3    Ramadan, G.A.4    Al Kedrah, S.S.5    Daoud, S.A.6
  • 75
    • 0036518288 scopus 로고    scopus 로고
    • The effect of oestradiol on vaginal collagen metabolism in postmenopausal women with genuine stress incontinence
    • Jackson S, James M, Abrams P (2002) The effect of oestradiol on vaginal collagen metabolism in postmenopausal women with genuine stress incontinence. Br J Obstet Gynaecol 109:339-344
    • (2002) Br J Obstet Gynaecol , vol.109 , pp. 339-344
    • Jackson, S.1    James, M.2    Abrams, P.3
  • 76
    • 20144383817 scopus 로고    scopus 로고
    • Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus
    • Helvering LM, Adrian MD, Geiser AG, Estrem ST, Wei T, Huang S et al (2005) Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus. Biol Reprod 72:830-841
    • (2005) Biol Reprod , vol.72 , pp. 830-841
    • Helvering, L.M.1    Adrian, M.D.2    Geiser, A.G.3    Estrem, S.T.4    Wei, T.5    Huang, S.6
  • 77
    • 0023251277 scopus 로고
    • Skin collagen changes in postmenopausal women receiving different regimens of estrogen therapy
    • Brincat M, Versi E, Moniz CF, Magos A, de Trafford J, Studd JW (1987) Skin collagen changes in postmenopausal women receiving different regimens of estrogen therapy. Obstet Gynecol 70:123-127
    • (1987) Obstet Gynecol , vol.70 , pp. 123-127
    • Brincat, M.1    Versi, E.2    Moniz, C.F.3    Magos, A.4    de Trafford, J.5    Studd, J.W.6
  • 78
    • 0036071330 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression by estrogen in fibroblasts that are derived from the pelvic floor
    • Moalli PA, Klingensmith WL, Meyn LA, Zyczynski HM (2002) Regulation of matrix metalloproteinase expression by estrogen in fibroblasts that are derived from the pelvic floor. Am J Obstet Gynecol 187:72-79
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 72-79
    • Moalli, P.A.1    Klingensmith, W.L.2    Meyn, L.A.3    Zyczynski, H.M.4
  • 79
    • 29144505088 scopus 로고    scopus 로고
    • 17beta-estradiol suppresses proliferation of fibroblasts derived from cardinal ligaments in patients with or without pelvic organ prolapse
    • Liu YM, Choy KW, Lui WT, Pang MW, Wong YF, Yip SK (2006) 17beta-estradiol suppresses proliferation of fibroblasts derived from cardinal ligaments in patients with or without pelvic organ prolapse. Hum Reprod 21:303-308
    • (2006) Hum Reprod , vol.21 , pp. 303-308
    • Liu, Y.M.1    Choy, K.W.2    Lui, W.T.3    Pang, M.W.4    Wong, Y.F.5    Yip, S.K.6
  • 80
    • 0037660810 scopus 로고    scopus 로고
    • Menstrual phase-dependent gene expression differences in periurethral vaginal tissue from women with stress incontinence
    • Chen B, Wen Y, Zhang ZM, Wang HB, Warrington JA, Polan ML (2003) Menstrual phase-dependent gene expression differences in periurethral vaginal tissue from women with stress incontinence. Am J Obstet Gynecol 189:89-97
    • (2003) Am J Obstet Gynecol , vol.189 , pp. 89-97
    • Chen, B.1    Wen, Y.2    Zhang, Z.M.3    Wang, H.B.4    Warrington, J.A.5    Polan, M.L.6
  • 81
    • 0028001421 scopus 로고
    • The anatomy of the pelvic floor
    • Delancey JO (1994) The anatomy of the pelvic floor. Curr Opin Obstet Gynecol 6:313-316
    • (1994) Curr Opin Obstet Gynecol , vol.6 , pp. 313-316
    • Delancey, J.O.1
  • 82
    • 0032840146 scopus 로고    scopus 로고
    • The relationships between vaginal collagen, plasma oestradiol and uterine prolapse in turkeys
    • Buchanan S, Robertson GW, Hocking PM (1999) The relationships between vaginal collagen, plasma oestradiol and uterine prolapse in turkeys. Research in Veterinary Science 67:153-157
    • (1999) Research in Veterinary Science , vol.67 , pp. 153-157
    • Buchanan, S.1    Robertson, G.W.2    Hocking, P.M.3
  • 84
    • 0033975284 scopus 로고    scopus 로고
    • Differential expression of matrix metalloproteinases and their tissue-derived inhibitors in cutaneous wound repair
    • Soo C, Shaw WW, Zhang X, Longaker MT, Howard EW, Ting K (2000) Differential expression of matrix metalloproteinases and their tissue-derived inhibitors in cutaneous wound repair. Plast Reconstr Surg 105:638-647
    • (2000) Plast Reconstr Surg , vol.105 , pp. 638-647
    • Soo, C.1    Shaw, W.W.2    Zhang, X.3    Longaker, M.T.4    Howard, E.W.5    Ting, K.6
  • 85
    • 22744448697 scopus 로고    scopus 로고
    • Mechanical signals regulating extracellular matrix gene expression in fibroblasts
    • Sarasa-Renedo A, Chiquet M (2005) Mechanical signals regulating extracellular matrix gene expression in fibroblasts. Scand J Med Sci Sports 15:223-230
    • (2005) Scand J Med Sci Sports , vol.15 , pp. 223-230
    • Sarasa-Renedo, A.1    Chiquet, M.2
  • 88
    • 3042811911 scopus 로고    scopus 로고
    • Matrix metalloproteinase activity and immunohistochemical profile of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 during human dermal wound healing
    • Gillard JA, Reed MW, Buttle D, Cross SS, Brown NJ (2004) Matrix metalloproteinase activity and immunohistochemical profile of matrix metalloproteinase-2 and -9 and tissue inhibitor of metalloproteinase-1 during human dermal wound healing. Wound Repair Regen 12:295-304
    • (2004) Wound Repair Regen , vol.12 , pp. 295-304
    • Gillard, J.A.1    Reed, M.W.2    Buttle, D.3    Cross, S.S.4    Brown, N.J.5
  • 89
    • 0024533893 scopus 로고
    • The role of partial denervation of the pelvic floor in the aetiology of genitourinary prolapse and stress incontinence of urine. A neurophysiological study
    • Smith AR, Hosker GL, Warrell DW (1989) The role of partial denervation of the pelvic floor in the aetiology of genitourinary prolapse and stress incontinence of urine. A neurophysiological study. Br J Obstet Gynaecol 96:24-28
    • (1989) Br J Obstet Gynaecol , vol.96 , pp. 24-28
    • Smith, A.R.1    Hosker, G.L.2    Warrell, D.W.3
  • 91
    • 34250634834 scopus 로고    scopus 로고
    • Functional anatomy of the female pelvic floor
    • Ashton-Miller JA, Delancey JO (2007) Functional anatomy of the female pelvic floor. Ann N Y Acad Sci 1101:266-296
    • (2007) Ann N Y Acad Sci , vol.1101 , pp. 266-296
    • Ashton-Miller, J.A.1    Delancey, J.O.2
  • 92
    • 0031655968 scopus 로고    scopus 로고
    • The effects of birth on urinary continence mechanisms and other pelvic-floor characteristics
    • Meyer S, Schreyer A, De Grandi P, Hohlfeld P (1998) The effects of birth on urinary continence mechanisms and other pelvic-floor characteristics. Obstet Gynecol 92:613-618
    • (1998) Obstet Gynecol , vol.92 , pp. 613-618
    • Meyer, S.1    Schreyer, A.2    De Grandi, P.3    Hohlfeld, P.4
  • 93
    • 0242412392 scopus 로고    scopus 로고
    • Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra
    • Cannon TW, Lee JY, Somogyi G, Pruchnic R, Smith CP, Huard J et al (2003) Improved sphincter contractility after allogenic muscle-derived progenitor cell injection into the denervated rat urethra. Urology 62:958-963
    • (2003) Urology , vol.62 , pp. 958-963
    • Cannon, T.W.1    Lee, J.Y.2    Somogyi, G.3    Pruchnic, R.4    Smith, C.P.5    Huard, J.6
  • 95
    • 34250863235 scopus 로고    scopus 로고
    • Autologous myoblasts and fibroblasts versus collagen for treatment of stress urinary incontinence in women: A randomised controlled trial
    • Strasser H, Marksteiner R, Margreiter E, Pinggera GM, Mitterberger M, Frauscher F et al (2007) Autologous myoblasts and fibroblasts versus collagen for treatment of stress urinary incontinence in women: A randomised controlled trial. Lancet 369:2179-2186
    • (2007) Lancet , vol.369 , pp. 2179-2186
    • Strasser, H.1    Marksteiner, R.2    Margreiter, E.3    Pinggera, G.M.4    Mitterberger, M.5    Frauscher, F.6
  • 97
    • 0037672732 scopus 로고    scopus 로고
    • Periurethral connective tissue status of postmenopausal women with genital prolapse with and without stress incontinence
    • Goepel C, Hefler L, Methfessel HD, Koelbl H (2003) Periurethral connective tissue status of postmenopausal women with genital prolapse with and without stress incontinence. Acta Obstet Gynecol Scand 82:659-664
    • (2003) Acta Obstet Gynecol Scand , vol.82 , pp. 659-664
    • Goepel, C.1    Hefler, L.2    Methfessel, H.D.3    Koelbl, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.