Differential elastin and tenascin immunolabeling in the uterosacral ligaments in postmenopausal women with and without pelvic organ prolapse

Acta Histochemica

Volumn 110, Issue 3, 2008, Pages 204-209

  Goepel, Christian ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Connective tissue; Elastin; Glycoproteins; Immunofluorescence; Pelvic floor; Pelvic organ prolapse; Tenascin; Uterosacral ligament; Women

Indexed keywords

COLLAGEN; ELASTIN; GLYCOPROTEIN; TENASCIN;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYSTERECTOMY; IMMUNOFLUORESCENCE MICROSCOPY; LIGAMENT; MAJOR CLINICAL STUDY; MUSCLE RELAXATION; PELVIC ORGAN PROLAPSE; PELVIS FLOOR; POSTMENOPAUSE; PROTEIN LOCALIZATION; UTEROSACRAL LIGAMENT;

AGED; AGED, 80 AND OVER; COLLAGEN; CONNECTIVE TISSUE; ELASTIN; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LIGAMENTS; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MYOMA; PELVIC FLOOR; POSTMENOPAUSE; SACRUM; TENASCIN; UTERINE PROLAPSE; UTERUS;

EID: 43049179553     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2007.10.014     Document Type: Article

References (27)

1. Amundsen C.L., Flynn B.J., and Webster G.D. Anatomical correction of vaginal vault prolapse by uterosacral ligament fixation in women who also require a pubovaginal sling. J Urol 169 (2003) 1770-1774
2. Bernstein E.F., Chen Y.Q., Tamai K., Shepley K.J., Resnik K.S., Zhang H., et al. Enhanced elastin and fibrillin gene expression in chronically photodamaged skin. J Invest Dermatol 103 (1994) 182-186
3. Bidmead J., and Cardozo L.D. Pelvic floor changes in the older woman. Br J Urol 82 (1998) 18-25
4. Boreham M.K., Wai C.Y., Miller R.T., Schaffer J.I., and Word R.A. Morphometric analysis of smooth muscle in the anterior vaginal wall of women with pelvic organ prolapse. Am J Obstet Gynecol 187 (2002) 56-63
5. Buller J.L., Thompson J.R., Cundiff G.W., Krueger Sullivan L., Schon Ybarra M.A., and Bent A.E. Uterosacral ligament: description of anatomic relationships to optimize surgical safety. Obstet Gynecol 97 (2001) 873-879
6. Bump R.C., and Norton P.A. Epidemiology and natural history of pelvic floor dysfunction. Obstet Gynecol Clin North Am 25 (1998) 723-746
7. Chadwick D., and Goode J. Ciba foundation symposium: the molecular biology and pathology of elastic tissues (1995), Wiley, New York
8. Cleary E. Skin. In: Comper W. (Ed). Extracellular matrix vol. 1 (1996), Harwood, Amsterdam 77-109 [Tissue Function]
9. DeLancey J.O.L. Anatomic aspects of vaginal eversion after hysterectomy. Am J Obstet Gynecol 166 (1992) 1717-1724
10. Ewies A.A., Al-Azzawi F., and Thompson J. Changes in extracellular matrix proteins in the cardinal ligaments of postmenopausal women with or without prolapse: a computerized immunohistomorphometric analysis. Hum Reprod 18 (2003) 2189-2195
11. Fazio M.J., Olsen D.R., Kuivaniemi H., Chu M.L., Davidson J.M., Rosenbloom J., et al. Isolation and characterization of human elastin cDNAs and age-associated variation in elastin gene expression in cultured skin fibroblasts. Lab Invest 58 (1988) 270-277
12. Jones F.S., and Jones P.L. The tenascin family of ECM glycoproteins: structure, function and regulation during embryonic development and tissue remodelling. Dev Dyn 218 (2000) 235-259
13. Liotta L.A., and Kohn E.C. The microenvironment of the tumor-host interface. Nature 411 (2001) 375-379
14. Liu S., Yang R., Al-Shaikh R., and Lane J. Collagen in tendons, ligaments and bone healing. Clin Orthopaed 318 (1995) 265-278
15. MacLennan A. The descent of woman. Climacteric 3 (2000) 225-226
16. Mokrzycki M., Mittal K., Smilen S., Blechman A., Porges R., and Demopolous R. Estrogen and progesterone receptors in the uterosacral ligament. Obstet Gynecol 90 (1997) 402-404
17. Neurath M. Expression of tenascin, laminin and fibronectin following traumatic rupture of the anterior cruciate ligament. Z Orthop 131 (1993) 168-172
18. Norton P., Boyd C., and Deak S. Collagen synthesis in women with genital prolapse or stress urinary incontinence. Neurol Urodyn 11 (1992) 300-301
19. Norton P., Baker J., Sharp H., and Warenski J. Genitourinary prolapse and joint hypermobility in women. Obstet Gynecol 85 (1995) 225-228
20. Pierce R., Mariani T., and Senior R. Elastin in lung development and disease. In: Chadwick D., and Goode J. (Eds). Ciba foundation symposium: the molecular biology and pathology of elastic tissues vol. 192 (1995), Wiley, New York 199-212
21. Scott J.E. Proteoglycan-fibrillar collagen interactions. Biochem J 252 (1988) 313-323
22. Smith A.R., Hosker G.L., and Warrell D.W. The role of partial denervation of the pelvic floor in the aetiology of genitourinary prolapse and stress incontinence of urine. A neurophysiological study. Br J Obstet Gynecol 96 (1989) 24-28
23. Uitto J., Fazio M., Bashir M., and Rosenbloom J. Elastic fibres of the connective tissue. In: Goldsmith L. (Ed). Physiology, biochemistry and molecular biology of the skin (1991), Oxford University Press, New York 533-557
24. Ulmsten U., and Falconer C. Connective tissue in female urinary incontinence. Curr Opin Obstet Gynecol 11 (1999) 509-515
25. Wallner K., Li C., Shah P.K., Fishbein M.C., Forrester J.S., Kaul S., et al. Tenascin-C is expressed in macrophage-rich human coronary atherosclerotic plaque. Circulation 99 (1999) 1284-1289
26. Yamamoto K., Yamamoto M., Akazawa K., Tajima S., Wakimoto H., and Aoyagi M. Decrease in elastin gene expression and protein synthesis in fibroblasts derived from cardinal ligaments of patients with prolapsus uteri. Cell Biol Int 21 (1997) 605-611
27. Yamamoto M., Akazawa K., Aoyagi M., and Yamamoto K. Changes in biological characteristics during the cellular aging of ligament fibroblasts derived from patients with prolapsus uteri. Mech Ageing Dev 115 (2000) 175-187