Growing steers grazing high versus low endophyte (Neotyphodium coenophialum) -infected tall fescue have reduced serum enzymes, increased hepatic glucogenic enzymes, and reduced liver and carcass mass

Journal of Animal Science

Volumn 87, Issue 2, 2009, Pages 748-760

  Brown, K R ^a   Anderson, G A ^a   Son, K ^a   Rentfrow, G ^a   Bush, L P ^a   Klotz, J L ^b   Strickland, J R ^b   Boling, J A ^a   Matthews, J C ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Alkaloid; Aspartate aminotransferase; Bovine; Liver; Phosphoenolpyruvate carboxykinase

Indexed keywords

AMINO ACID TRANSPORTER; ENZYME; MINERAL;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; BLOOD; BLOOD CELL; BODY WEIGHT; CATTLE; CATTLE DISEASE; COMPARATIVE STUDY; CYTOLOGY; ENZYMOLOGY; ERGOTISM; FESCUE; LIVER; MALE; MEAT; METABOLISM; MICROBIOLOGY; NEOTYPHODIUM; ORGAN SIZE; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; STANDARD;

AMINO ACID TRANSPORT SYSTEMS; ANIMAL FEED; ANIMALS; BLOOD CELLS; BODY WEIGHT; CATTLE; CATTLE DISEASES; ENZYMES; ERGOTISM; FESTUCA; LIVER; MALE; MEAT; MINERALS; NEOTYPHODIUM; ORGAN SIZE; RANDOM ALLOCATION;

BOS; BOVINAE; FESTUCA ARUNDINACEA; NEOTYPHODIUM COENOPHIALUM;

EID: 62249126273     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2008-1108     Document Type: Article

References (82)

1. Amundson, J. L., T. L. Mader, R. J. Rasby, and Q. S. Hu. 2006. Environmental effects on pregnancy rate in beef cattle. J. Anim. Sci. 84:3415-3420.
2. Barnett, P. S., E. Palazidou, J. P. Mitchell, P. B. Coskeran, J. Butler, J. M. Dawson, J. Maccabe, and A. M. McGregor. 1991. Endocrine function, psychiatric and clinical consequences in patients with macroprolactinomas after long-term treatment with the new non-ergot dopamine agonist CV205-502. Q. J. Med. 81:891-906.
3. Beck, P. A., S. A. Gunter, K. S. Lusby, C. P. West, K. B. Watkins, and D. S. Hubbell III. 2008. Animal performance and economic comparison of novel- and toxic-endophyte tall fescues to cool-season annuals. J. Anim. Sci. doi:10.2527/jas.2007-0522.
4. Ben-Jonathan, N., L. A. Arbogast, and J. F. Hyde. 1989. Neuroendocrine regulation of prolactin release. Prog. Neurobiol. 33:399-447.
5. Bernard, J. K., A. B. Chestnut, B. H. Erickson, and F. M. Kelly. 1993. Effects of prepartum consumption of endophyte-infected tall fescue on serum prolactin and subsequent milk production of Holstein cows. J. Dairy Sci. 76:1928-1933.
6. Bhusari, S., L. B. Hearne, D. E. Spiers, W. R. Lamberson, and E. Antoniou. 2006. Effect of fescue toxicosis on hepatic gene expression in mice. J. Anim. Sci. 84:1600-1612.
7. Brancaccio, P., N. Maffulli, R. Buonauro, and F. M. Limongelli. 2007. Serum enzyme monitoring in sports medicine. Clin. Sports Med. 27:1-18.
8. Brown, M. A., W. A. Phillips, A. H. Brown Jr., S. W. Coleman, W. G. Jackson, and J. R. Miesner. 1999. Postweaning performance of calves from Angus, Brahman, and reciprocal-cross cows grazing endophyte-infected tall fescue or common bermudagrass. J. Anim. Sci. 77:25-31.
9. Browning, R. Jr., and M. L. Leite-Browning. 1997. Effects of ergotamine and ergonovine on thermal regulation and cardiovascular function in cattle. J. Anim. Sci. 75:176-181.
10. Bush, L., J. Boling, and S. Yates. 1979. Animal disorders. Pages 247-292 in Tall Fescue. R. C. Buckner and L. P. Bush, ed. Am. Soc. Agron., Madison, WI.
11. Cardinet, G. H., J. F. Littrell, and R. A. Freedland. 1967. Comparative investigations of serum creatine Phosphokinase and glutamic-oxaloacetate transaminase activities in equine paralytic myoglobinuria. Res. Vet. Sci. 8:219-226.
12. Chan, C., F. Berthiaume, K. Lee, and M. L. Yarmush. 2003. Metabolic flux analysis of hepatocyte function in hormone- and amino acid-supplemented plasma. Metab. Eng. 5:1-15.
13. Cheeke, P. R. 1995. Endogenous toxins and mycotoxins in forage grasses and their effects on livestock. J. Anim. Sci. 73:909-918.
14. Chestnut, A. B., P. D. Anderson, M. A. Cochran, A. Fribourg, and K. D. Gwinn. 1992. Effects of hydrated sodium calcium aluminosilicate on fescue toxicosis and mineral absorption. J. Anim. Sci. 70:2838-2846.
15. Cincotta, A. H., and A. H. Meier. 1989. Reductions of body fat stores and total plasma cholesterol and triglyceride concentrations in several species by bromocryptine treatment. Life Sci. 45:2247-2254.
16. Crawford, R. J., J. R. Forwood, R. L. Belyea, and G. B. Gardner. 1989. Relationship between level of endophyte infection and cattle gains in tall fescue. J. Prod. Agric. 2:147-150.
17. Da Fonseca-Wollheim, F. 1973. The significance of the hydrogen ion concentration and the addition of ADP in the determination of ammonia with glutamate dehydrogenase. An improved enzymatic determination of ammonia. Clin. Biochem. 10:421-425.
18. Daniels, L. B., A. Ahmed, T. S. Nelson, E. L. Piper, and J. N. Beasley. 1984. Physiological responses in pregnant white rabbits given a chemical extract of toxic tall fescue. Nutr. Rep. Int. 29:505-510.
19. Davenport, G. M., J. A. Boling, and C. H. Rahe. 1993. Growth and endocrine responses of cattle to implantation of estradiol-17 beta during continuous or discontinuous grazing of high- and low-endophyte-infected tall fescue. J. Anim. Sci. 71:757-764.
20. Dehnes, Y., F. A. Chaudhry, K. Ullensvang, K. P. Lehre, J. StormMathisen, and N. C. Danbolt. 1998. The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia. J. Neurosci. 18:3606-3619.
21. Ding, G. J., P. A. Fischer, R. C. Boltz, J. A. Schmidt, J. J. Colaianne, A. Gough, R. A. Rubin, and D. K. Miller. 1998. Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system. J. Biol. Chem. 273:28897-28905.
22. Dougherty, C. T., L. M. Lauriault, N. W. Bradley, N. Gay, and P. L. Cornelius. 1991. Induction of tall fescue toxicosis in heatstressed cattle and its alleviation with thiamin. J. Anim. Sci. 69:1008-1018.
23. Duehlmeier, R., K. Sammet, A Widdel, W. von Engelhardt, U. Wernery, J. Kinne, and H.-P. Sallman. 2007. Distribution patterns of the glucose transporters GLUT4 and GLUTI in skeletal muscles of rats (Rattus norvegicus), pigs (Sus seroja), cows (Bos taurus), adult goats, goat kids (Capra hircus), and camels (Camelus dromedaries). Comp. Biochem. Physiol. A 146:274-282.
24. Duncan, J. R., K. W. Prasse, and E. A. Mahaffey. 1994. Veterinary Laboratory Medicine: Clinical Pathology. 3rd ed. Iowa State Univ. Press, Ames.
25. Fan, M. Z., J. C. Matthews, N. M. Etienne, B. Stoll, D. Lackeyram, and D. G. Burrin. 2004. Expression of apical membrane L-glutamate transporters in neonatal porcine epithelial cells along the small intestinal crypt-villus axis. Am. J. Physiol. Gastrointest. Liver Physiol. 287:G385-G398.
26. Finco, D. R. 1997. Kidney function. Page 443 in Clinical Biochemistry of Domestic Animals. J. Kaneko. 5th ed. Academic Press, San Diego, CA.
27. Fiorito, I. M., L. D. Bunting, G. M. Davenport, and J. A. Boling. 1991. Metabolic and endocrine responses of lambs fed acremonium-coenophialum-infected or noninfected tall fescue hay at equivalent nutrient intake. J. Anim. Sci. 69:2108-2114.
28. Fleisher, G. A., and K. G. Wakim. 1963a. The fate of enzymes in body fluids-An experimental study I. Disappearance rates of glutamic-pyruvic transaminase under various conditions. J. Lab. Clin. Med. 61:76-85.
29. Fleisher, G. A., and K. G. Wakim. 1963b. The fate of enzymes in body fluids-An experimental study II. Disappearance rates of glutamic-oxalacetic transaminase II under various conditions. J. Lab. Clin. Med. 61:98-106.
30. Freeman, M. E., B. Kanyicska, A. Lerant, and G. Nagy. 2000. Prolactin: Structure, function, and regulation of secretion. Physiol. Rev. 80:1523-1631.
31. Goetsch, A. L., A. L. Jones, S. R. Stokes, K. W. Beers, and E. L. Piper. 1987. Intake, digestion, passage rate and serum prolactin in growing dairy steers fed endophyte-infected fescue with uoninfected fescue, clover and wheat straw. J. Anim. Sci. 64:1759-1768.
32. Groff, J. L., and S. S. Gropper. 2000. Protein. Pages 185-188 in Advanced Nutrition and Human Metabolism. 3rd ed. Wadsworth, Belmont, CA.
33. Hahn, G. L. 1999. Dynamic responses of cattle to thermal heat loads. J. Anim. Sci. 77:10-20.
34. Hahn, G. L., and T. L. Mader. 1997. Heat waves in relation to thermoregulation, feeding behavior and mortality of feedlot cattle. Pages 563-571 in Proc. 5th Int. Livest. Environ. Symp. (Vol. I). ASAE SP-01-97. Am. Soc. Agric. Eng., St. Joseph, MI.
35. Harris, P. 1997. Equine rhabdomyolysis symdrome. Pages 115-121 in Current therapy in equine medicine 4. N. E. Robinson, ed. W. B. Saunders Company, Philadelphia, PA.
36. Häussinger, D. 1986. Regulation of hepatic ammonia metabolism: The intercellular glutamine cycle. Adv. Enzyme Regul. 25:159-180.
37. Hemken, R. W., J. A. Boling, L. S. Bull, R. H. Hatton, R. C. Buckner, and L. P. Bush. 1981. Interaction of environmental temperature and anti-quality factors on the severity of summer fescue toxicosis. J. Anim. Sci. 52:710-714.
38. Hemken, R. W., J. A. Jackson Jr., and J. A. Boling. 1984. Toxic factors in tall fescue. J. Anim. Sci. 58:1011-1016.
39. Hill, N. S., D. P. Belesky, and W. C. Stringer. 1991. Competitiveness of tall fescue as influenced by Acremonium coenophialum. Crop Sci. 31:185-190.
40. Hoveland, C. S. 1993. Economic importance of Acremonium endophytes. Agrie. Ecosyst. Environ. 44:3-12.
41. Hoveland, C. S., S. P. Schmidt, C. C. King Jr., J. W. Odom, E. M. Clark, J. A. McGuire, L. A. Smith, H. W. Grimes, and J. L. Holliman. 1983. Steer performance and association of Acremonium coenophialum fungal endophyte on tall fescue pasture. Agron. J. 75:821-824.
42. Howell, J. A., A. D. Matthews, K. C. Swanson, D. L. Harmon, and J. C. Matthews. 2001. Molecular identification of high-affinity glutamate transporters in sheep and cattle forestomach, intestine, liver, kidney, and pancreas. J. Anim. Sci. 79:1329-1336.
43. Howell, J. A., A. D. Matthews, K. C. Swanson, D. L. Harmon, and J. C. Matthews. 2003. Content of ileal EAAC1 and hepatic GLT-1 high-affinity glutamate transporters is increased in growing vs. nongrowing lambs, paralleling increased tissue D- and Lglutamate, plasma glutamine, and alanine concentrations. J. Anim. Sci. 81:1030-1039.
44. Huber, K., J. Petzold, C. Rehfeldt, K. Ender, and I. Fiedler. 2007. Muscle energy metabolism: structural and functional features in different types of porcine striated muscles. J. Muscle Res. Cell Motil. 28:249-258.
45. Kaneko, J. J., J. W. Harvey, and M. L. Bruss. 1997. Clinical Biochemistry of Domestic Animals. 5th ed. Academic Press, San Diego, CA.
46. Kenward, M. G., and J. H. Roger. 1997. Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 53:983-997.
47. Kilberg, M. S. 1989. Measurement of amino acid transport by hepatocytes in suspension and monolayer culture. Methods Enzymol. 173:564-575.
48. LCI. 1970. Patterns of Transit Losses. Livestock Conservation Inc., Omaha, NE.
49. Lobley, G. E., and G. D. Milano. 1997. Regulation of hepatic nitrogen metabolism in ruminants. Proc. Nutr. Soc. 56:547-563.
50. Mader, T. L., S. M. Holt, G. L. Halm, M. S. Davis, and D. E. Spiers. 2002. Feeding strategies for managing heat load in feedlot cattle. J. Anim. Sci. 80:2373-2382.
51. Matthews, J. C. 2005. Expression and function of non-organelle glutamate transporters to support peripheral tissue function. 2005. Pages 47-75 in Glutamate Receptors in Peripheral Tissues: Excitatory Transmission Outside the CNS. S. Gill and O. Pulido, ed. Kluwer Academic/Plenum Press, New York, NY.
52. Monroe, J. L., D. L. Cross, L. W. Hudson, D. M. Henricks, S. W. Kennedy, and W. C. Bridges Jr. 1988. Effect of selenium and endophyte-contaminated fescue on performance and reproduction in mares. Equine Vet. Sci. 8:148-153.
53. Nihsen, M. E., E. L. Piper, C. P. West, R. J. Crawford Jr., T. M. Denard, Z. B. Johnson, C. A. Roberts, D. A. Spiers, and C. F. Rosenkrans Jr. 2004. Growth rate and physiology of steers grazing tall fescue inoculated with novel endophytes. J. Anim. Sci. 82:878-883.
54. Oliver, J. W. 1997. Physiological manifestations of endophyte toxicosis in ruminant and laboratory species. Pages 311-346 in Neotyphodium/Grass Interactions. C. W. Bacon and N. S. Hill, ed. Plenum Press, New York, NY.
55. Oliver, J. W., A. E. Schultze, B. W. Rohrbach, H. A. Fribourg, T. Ingle, and J. C. Waller. 2000. Alterations in hemograms and serum biochemical analytes of steers after prolonged consumption of endophyte-infected tall fescue. J. Anim. Sci. 78:1029-1035.
56. Pahua, D. N., and H. F. DeLuca. 1981. Stimulation of intestinal calcium transport and calcium mobilization by prolactin in vitamin D-deficient rats. Science 214:1038-1039.
57. Peters, L. L., M. T. Hoefer, and N. Ben-Jonathan. 1981. The posterior pituitary: Regulation of anterior pituitary prolactin secretion. Science 213:659-661.
58. Porter, J. K., J. D. Robbins, W. P. Norred, G. B. Garner, and C. W. Bacon. 1985. Serum prolactin and brain catecholamine metabolite depression in rats administered extracts of endophyteinfected fescue. J. Agrie. Food Chem. 33:34-36.
59. Porter, J. K., and F. N. Thompson Jr. 1992. Effects of fescue toxicosis on reproduction in livestock. J. Anim. Sci. 70:1594-1603.
60. Realini, C. E., S. K. Duckett, N. S. Hill, C. S. Hoveland, B. G. Lyon, J. R. Sackmann, and M. H. Gillis. 2005. Effect of endophyte type on carcass traits, meat quality, and fatty acid composition of beef cattle grazing tall fescue. J. Anim. Sci. 83:430-439.
61. Sattler, T., and M. Fürll. 2004. Creatine kinase and aspartate aminotransferase in cows as indicators for endometritis. J. Vet. Med. 51:132-137.
62. Schillo, K. K., L. S. Leshin, J. A. Boling, and N. Gay. 1988. Effects of endophyte-infected fescue on concentrations of prolactin in blood sera and the anterior pituitary and concentrations of dopamine and dopamine metabolites in brain of steers. J. Anim. Sci. 66:713-718.
63. Schmidt, S. P., C. S. Hoveland, E. M. Clark, N. D. Davis, L. Aubrey Smith, H. W. Grimes, and J. L. Holliman. 1982. Association of an endophytic fungus with fescue toxicity in steers fed Kentucky-31 tall fescue seed or hay. J. Anim. Sci. 55:1259-1263.
64. Schultze, A. E., B. W. Rohrbach, H. A. Fribourg, J. C. Waller, and J. W. Oliver. 1999. Alterations in bovine serum biochemistry profiles associated with prolonged consumption of endophyte-infected tall fescue. Vet. Hum. Toxicol. 41:133-139.
65. Settivari, R. S., S. Bhusari, T. Evans, P. A. Eichen, L. B. Hearne, E. Antoniou, and D. E. Spiers. 2006. Genomic analysis of the impact of fescue toxicosis on hepatic function. J. Anim. Sci. 84:1279-1294.
66. Shennan, B. 1994. Regulation of water and solute transport across mammalian plasma cell membranes by prolactin. J. Dairy Res. 61:155-166.
67. -1- erythoid progenitors and replaces EpoR in a synergistic interaction with c-kit. Blood 92:1491-1496.
68. Stier, C. T., E. A. Cowden, H. G. Friesen, and M. E. M. Allison. 1984. Prolactin and the rat kidney: a clearance and micropuncture study. Endocrinology 115:362-367.
69. Stockham, S. L., and M. A. Scott. 2002. Proteins. Pages 264-265 in Fundamentals of Veterinary Clinical Pathology. Iowa State Press, Ames.
70. Strickland, J. R., D. L. Cross, T. C. Jenkins, R. J. Petroski, and R. G. Powell. 1992. The effect of alkaloids and seed extracts of endophyte-infected fescue on prolactin secretion in an in vitro rat pituitary perfusion system. J. Anim. Sci. 70:2779-2786.
71. Strickland, J. R., J. W. Oliver, and D. L. Cross. 1993. Fescue toxicosis and its impact on animal agriculture. Vet. Hum. Toxicol. 35:454-464.
72. Stuedemann, J. A., and C. S. Hoveland. 1988. Fescue endophyte: History and impact on animal agriculture. J. Prod. Agrie. 1:39-44.
73. Stuedemann, J. A., S. R. Wilkinson, D. P. Belesky, C. S. Hoveland, O. J. Devine, F. W. Thompson, H. S. Campbell, W. E. Townsend, and H. Ciordia. 1986. Effect of level of fungus and nitrogen fertilization rate of KY-31 tall fescue on steer performance. J. Anim. Sci. 63(Suppl.):290 (Abstr.)
74. Stuedemann, J. A., S. R. Wilkinson, D. J. Williams, H. Cioridia, J. V. Ernst, W. A. Jackson, and J. B. Jones Jr. 1975. Long-term broiler litter fertilization of tall fescue pastures and health and performance of beef cows. Pages 264-268 in Managing Livestock Wastes, Proc. 3rd Int. Symp. Livestock Wastes, Champaign, IL. ASAE, St. Joseph, MI.
75. Tennant, B. C. 1997. Hepatic function. Pages 337-338 and 346 in Clinical Biochemistry of Domestic Animals. 5th ed. J. Kaneko, ed. Academic Press, San Diego, CA.
76. Thorn, E. C. 1959. The discomfort index. Weatherwise 12:57-59.
77. Thompson, F. N., and J. A. Stuedemann. 1993. Pathophysiology of fescue toxicosis. Agric. Ecosyst. Environ. 44:263-281.
78. Turk, J. R., and S. W. Casteel. 1997. Clinical Biochemistry in Toxicology. Page 829 in Clinical Biochemistry of Domestic Animals. 5th ed. J. Kaneko, ed. Academic Press, San Diego, CA.
79. USDA. 1997. United States Standards for Beef Carcasses. Livest. Seed Program, Agrie. Market. Serv., Des Moines, IA.
80. Wakim, K. G., and G. A. Fleisher. The fate of enzymes in body fluids-An experimental study II. Disappearance rates of glutamic-oxalacetic transaminase I under various conditions. J. Lab. Clin. Med. 61:86-97.
81. Yamin, T. T., J. M. Ayala, and D. K. Miller. 1996. Activation of the native 45-kDa precursor form on interleuking-1-converting enzyme. J. Biol. Chem. 271:13273-13282.
82. Yates, S. G., and R. G. Powell. 1988. Analysis of ergopeptide alkaloids in endophyte-infected tall fescue. J. Agrie. Food Chem. 36:337-340.