Opioid, cannabinoid CB1 and NOP receptors do not mediate APAP-induced hypothermia in rats

Pharmacology Biochemistry and Behavior

Volumn 92, Issue 3, 2009, Pages 503-507

  Corley, Gladys ^a   Rawls, Scott M ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

APAP; Cannabinoid; CB1; Delta; Hypothermia; Kappa; Nociceptin; NOP; Opioid

Indexed keywords

CANNABINOID 1 RECEPTOR; N (4 AMINO 2 METHYL 6 QUINOLINYL) 2 (4 ETHYLPHENOXYMETHYL)BENZAMIDE; NALTREXONE; NALTRINDOLE; NOCICEPTIN RECEPTOR; NORBINALTORPHIMINE; OPIATE RECEPTOR; PARACETAMOL; RIMONABANT; AMINOQUINOLINE DERIVATIVE; BENZAMIDE DERIVATIVE; DRUG DERIVATIVE; N-(4-AMINO-2-METHYLQUINOLIN-6-YL)-2-(4-ETHYLPHENOXYMETHYL)BENZAMIDE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CRYOANESTHESIA; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ACETAMINOPHEN; AMINOQUINOLINES; ANIMALS; BENZAMIDES; BODY TEMPERATURE; HYPOTHERMIA, INDUCED; MALE; NALTREXONE; PIPERIDINES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RECEPTORS, OPIOID;

EID: 62249085382     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.01.020     Document Type: Article

References (50)

1. Anderson B.J., Holford N.H., Woollard G.A., and Chan P.L. Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children. Br J Clin Pharmacol 46 (1998) 237-243
2. Aronoff D.M., and Romanovsky A.A. Eicosanoids in non-febrile thermoregulation. Prog Brain Res 162 (2007) 15-25
3. Ayoub S.S., Botting R.M., Goorha S., Colville-Nash P.R., Willoughby D.A., and Ballou L.R. APAP-induced hypothermia in mice is mediated by a prostaglandin endoperoxide synthase 1 gene-derived protein. Proc Natl Acad Sci U S A 101 (2004) 11165-11169
4. Ayoub S.S., Colville-Nash P.R., Willoughby D.A., and Botting R.M. The involvement of a cyclooxygenase 1 gene-derived protein in the antinociceptive action of paracetamol in mice. Eur J Pharmacol 538 (2006) 57-65
5. Baker A.K., and Meert T.F. Functional effects of systemically administered agonists and antagonists of mu, delta, and kappa opioid receptor subtypes on body temperature in mice. J Pharmacol Exp Ther 302 (2002) 1253-1264
6. Björkman R. Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol, Experimental studies in the rat. Acta Anaesthesiol Scand Suppl 103 (1995) 1-44
7. Blakley G.G., Pohorecky L.A., and Benjamin D. Behavioral and endocrine changes following antisense oligonucleotide-induced reduction in the rat NOP receptor. Psychopharmacology (Berl) 171 (2004) 421-428
8. Botting R., and Ayoub S.S. COX-3 and the mechanism of action of paracetamol/acetaminophen. Prostaglandins Leukot Essent Fatty Acids 72 (2005) 85-87
9. Bujalska M. Effect of nonselective and selective opioid receptors antagonists on antinociceptive action of APAP [part III]. Pol J Pharmacol 56 (2004) 539-545
10. Canini F., Bourdon L., and Bittel J. Effect of ambient temperatures ranging from cold to heat on thermoregulation in conscious MK801-treated rats. Can J Physiol Pharmacol 81 (2003) 959-965
11. Chandrasekharan N.V., Dai H., Roos K.L., Evanson N.K., Tomsik J., Elton T.S., et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A 99 (2002) 13926-13931
12. Chen X., McClatchy D.B., Geller E.B., Liu-Chen L., Tallarida R.J., and Adler M.W. Possible mechanism of hypothermia induced by intracerebroventricular injection of orphanin FQ/nociceptin. Brain Res 904 (2001) 252-258
13. Compton D.R., Gold L.H., Ward S.J., Balster R.L., and Martin B.R. Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol. J Pharmacol Exp Ther 263 (1992) 1118-1126
14. Courade J.P., Caussade F., Martin K., Besse D., Delchambre C., Hanoun N., et al. Effects of acetaminophen on monoaminergic systems in the rat central nervous system. Naunyn Schmiedebergs Arch Pharmacol 364 (2001) 534-537
15. Denes E., Amaniou M., Rogez J.P., Weinbreck P., and Merle L. APAP-induced hypothermia, an AIDS related side-effect? About 4 cases. Ann Med Interne (Paris) 153 (2004) 411-413
16. Dippel D.W., van Breda E.J., van der Worp H.B., van Gemert H.M., Kappelle L.J., Algra A., et al. Timing of the effect of APAP on body temperature in patients with acute ischemic stroke. Neurology 61 (2003) 677-679
17. Feleder C., Perlik V., and Blatteis C.M. Preoptic alpha 1- and alpha 2-noradrenergic agonists induce, respectively, PGE2-independent and PGE2-dependent hyperthermic responses in guinea pigs. Am J Physiol Regul Integr Comp Physiol 286 (2004) R1156-1166
18. Feleder C., Perlik V., and Blatteis C.M. Preoptic nitric oxide attenuates endotoxic fever in guinea pigs by inhibiting the POA release of norepinephrine. Am J Physiol Regul Integr Comp Physiol 293 (2007) R1144-1151
19. Geller E.B., Hawk C., Tallarida R.J., and Adler M.W. Postulated thermoregulatory roles for different opiate receptors in rats. Life Sci 31 (1982) 2241-2244
20. Gourine A.V. Pharmacological evidence that nitric oxide can act as an endogenous antipyretic factor in endotoxin-induced fever in rabbits. Gen Pharmacol 26 (1995) 835-841
21. Granados-Soto V., Flores-Murrieta F.J., López-Muñoz F.J., Salazar L.A., Villarreal J.E., and Castañeda-Hernández G. Relationship between paracetamol plasma levels and its analgesic effect in the rat. J Pharm Pharmacol 44 (1992) 741-744
22. Handler C.M., Geller E.B., and Adler M.W. Effect of mu-, kappa-, and delta-selective opioid agonists on thermoregulation in the rat. Pharmacol Biochem Behav 43 (1992) 1209-1216
23. Higgins G.A., Grottick A.J., Ballard T.M., Richards J.G., Messer J., Takeshima H., et al. Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function. Neuropharmacology 41 (2001) 97-107
24. Hinz B., and Brune K. Antipyretic analgesics: nonsteroidal antiinflammatory drugs, selective COX-2 inhibitors, paracetamol and pyrazolinones. Handb Exp Pharmacol 177 (2007) 65-93
25. Huang W.T., Wang J.J., and Lin M.T. Antipyretic effect of APAP by inhibition of glutamate release after staphylococcal enterotoxin A fever in rabbits. Neurosci Lett 355 (2004) 33-36
26. Hunskaar S., Berge O.G., and Hole K. A modified hot-plate test sensitive to mild analgesics. Behav Brain Res 21 (1986) 101-108
27. Li S., Dou W., Tang Y., Goorha S., Ballou L.R., and Blatteis C.M. APAP: antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant. Prostaglandins Other Lipid Mediat 85 (2008) 89-99
28. Maharaj D.S., Saravanan K.S., Maharaj H., Mohanakumar K.P., and Daya S. Acetaminophen and aspirin inhibit superoxide anion generation and lipid peroxidation, and protect against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats. Neurochem Int 44 (2004) 355-360
29. Maharaj D.S., Maharaj H., Daya S., and Glass B.D. Melatonin and 6-hydroxymelatonin protect against iron-induced neurotoxicity. J Neurochem. 96 (2006) 78-81
30. Massey T.E., Walker R.M., McElligott T.F., and Racz W.J. Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. Toxicology 25 (1982) 187-200
31. Meunier J.C. Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor. Eur J Pharmacol 340 (1997) 1-15
32. Mollereau C., and Mouledous L. Tissue distribution of the opioid receptor-like (ORL1) receptor. Peptides 21 (2000) 907-917
33. Oborilová A., Mayer J., Pospísil Z., and Korístek Z. Symptomatic intravenous antipyretic therapy: efficacy of metamizol, diclofenac, and propacetamol. J Pain Symptom Manage 24 (2002) 608-615
34. Ottani A., Leone S., Sandrini M., Ferrari A., and Bertolini A. The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors. Eur J Pharmacol 531 1-3 (2006) 280-281
35. Pelissier T., Alloui A., Caussade F., Dubray C., Cloarec A., Lavarenne J., et al. Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence. J Pharmacol Exp Ther 278 (1996) 8-14
36. Pini L.A., Vitale G., Ottani A., and Sandrini M. Naloxone-reversible antinociception by paracetamol in the rat. J Pharmacol Exp Ther 280 (1997) 934-940
37. Polk D.L., and Lipton J.M. Effects of sodium salicylate, aminopyrine and chlorpromazine on behavioral temperature regulation. Pharmacol Biochem Behav 3 (1975) 167-172
38. Prescott L.F. Paracetamol: past, present, and future. Am J Ther 7 (2000) 143-147
39. Rawls S.M., Cabassa J., Geller E.B., and Adler M.W. CB1 receptors in the preoptic anterior hypothalamus regulate WIN 55212-2 [(4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1ij]quinolin-6-one]-induced hypothermia. J Pharmacol Exp Ther 301 (2002) 963-968
40. Rawls S.M., Hewson J.M., Inan S., and Cowan A. Brain delta2 opioid receptors mediate SNC-80-evoked hypothermia in rats. Brain Res 1049 (2005) 61-69
41. Rawls S.M., Schroeder J.A., Ding Z., Rodriguez T., and Zaveri N. NOP receptor antagonist, JTC-801, blocks cannabinoid-evoked hypothermia in rats. Neuropeptides 41 (2007) 239-247
42. Sandrini M., Vitale G., Pini L.A., Lopetuso G., Romualdi P., and Candeletti S. Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. Eur J Pharmacol 507 (2005) 43-48
43. Satinoff E. Salicylate: action on normal body temperature in rats. Science 176 (1972) 532-533
44. Simmons D.L., Wagner D., and Westover K. Nonsteroidal anti-inflammatory drugs, acetaminophen, cyclooxygenase 2, and fever. Clin Infect Dis 31 Suppl 5 (2000) S211-218
45. Spencer R.L., Hruby V.J., and Burks T.F. Body temperature response profiles for selective mu, delta and kappa opioid agonists in restrained and unrestrained rats. J Pharmacol Exp Ther 246 (1988) 92-101
46. Uezu K., Sei H., Sano A., Toida K., Suzuki-Yamamoto T., Houtani T., et al. Lack of nociceptin receptor alters body temperature during resting period in mice. Neuroreport 15 (2004) 751-755
47. Van Tittelboom T., and Govaerts-Lepicard M. Hypothermia: an unusual side effect of paracetamol. Vet Hum Toxicol 31 (1989) 57-59
48. Walker R.M., Massey T.E., McElligott T.F., and Racz W.J. APAP-induced hypothermia, hepatic congestion, and modification by N-acetylcysteine in mice. Toxicol Appl Pharmacol 59 (1981) 500-507
49. Wang Y., Chen Y., Xu W., Lee D.Y., Ma Z., Rawls S.M., Cowan A., and Liu-Chen L.Y. 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. J Pharmacol Exp Ther 324 (2008) 1073-1083
50. Yakimova K.S., and Pierau F.K. Nociceptin/orphanin FQ: effects on thermoregulation in rats. Methods Find Exp Clin Pharmacol 21 (1999) 345-352