Fatty acids and postprandial inflammation

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 12, Issue 2, 2009, Pages 129-137

  Margioris, Andrew N ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

C reactive protein; N 3 and n 6 polyunsaturated fatty acids; Postprandial inflammation

Indexed keywords

ACUTE PHASE PROTEIN; CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; SATURATED FATTY ACID;

ADIPOCYTE; CARDIOVASCULAR DISEASE; FOOD INDUSTRY; FOOD INTAKE; FOOD QUALITY; GLYCEMIC INDEX; HUMAN; INFLAMMATION; INSULIN RESISTANCE; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LIFESTYLE MODIFICATION; MACROPHAGE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRITIONAL VALUE; OBESITY; OXIDATIVE STRESS; POSTPRANDIAL STATE; REVIEW;

CARDIOVASCULAR DISEASES; DIETARY FATS; FATTY ACIDS; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; HUMANS; INFLAMMATION; POSTPRANDIAL PERIOD;

EID: 62149108596     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: 10.1097/MCO.0b013e3283232a11     Document Type: Review

References (49)

1. Hansen K, Sickelmann F, Pietrowsky R, et al. Systemic immune changes following meal intake in humans. Am J Physiol 1997; 273:R548-R553.
2. Burdge GC, Calder PC. Plasma cytokine response during the postprandial period: a potential causal process in vascular disease? BrJ Nutr 2005; 93:3-9.
3. Bell DS, O'Keefe JH, Jellmger P. Postprandial dysmetabolism: the missing link between diabetes and cardiovascular events? Endocr Pract 2008; 14:112-124.
4. O'Keefe JH, Gheewala NM, O'Keefe JO. Dietary strategies for improving postprandial glucose, lipids, inflammation, and cardiovascular health. J Am Coll Cardiol 2008; 51:249-255.
5. Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444:860-867. A tour-de-force on metabolic inflammation from the pioneer on this subject. A 'must'-read article.
6. Wellen KE, Fucho R, Gregor MF, et al. Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell 2007; 129:537-548. An excellent study from the pioneers in the field of metabolic inflammation describing an interesting pathophysiological mechanism responsible for the chronic low-grade metabolic inflammation of obesity and most probably of the hyperresponse of the obese to high-fat diets. The STAMP2 membrane receptor in adipocytes blocks the TLR4 inflammatory cascade; its expression decreases as the visceral adipocyle accumulates triglycerides in obesity. A 'must'-read article. See also the excellent comments of Abedini and Shoelson in Ref. [7].
7. Abedini A, Shoelson SE. Inflammation and obesity: STAMPing out insulin resistance? Immunol Cell Biol 2007; 85:399-400. Excellent comments on the Hotamisligil's group paper on STAMP2.
8. Blackburn P, Després JP, Lamarche B, et al. Postprandial variations of plasma inflammatory markers in abdominally obese men. Obesity 2006; 14:1747-1754.
9. Jellema A, Plat J, Mensink RP. Weight reduction, but not a moderate intake of fish oil, lowers concentrations of inflammatory markers and PAI-1 antigen in obese men during the fasting and postprandial state. Eur J Clin Invest 2004; 34:766-773.
10. Plat J, Jellema A, Ramakers J, Mensink RP. Weight loss, but not fish oil consumption, improves fasting and postprandial serum lipids, markers of endothelial function, and inflammatory signatures in moderately obese men. J Nutr 2007; 137:2635-2640.
11. Nappo F, Esposito K, Michele Cioffi M, et al. Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals. Am Coll Cardiol 2002; 39:1145-1150.
12. Esposito K, Ciotola M, Sasso FC, et al. Effect of a single high-fat meal on endothelial function in patients with the metabolic syndrome: role of tumor necrosis factor-alpha. Nutr Metab Cardiovasc Dis 2007; 17:274-279.
13. Taki K, Nishio K, Hamajima N, Niwa T. Metabolic syndrome defined by new criteria in Japanese is associated with increased liver enzymes and C-reactive protein. Nagoya J Med Sci 2008; 70:1-9.
14. Wautier JL, Boulanger E, Wautier MP. Postprandial hyperglycemia alters inflammatory and hemostatic parameters. Diabetes Metab 2006; 32:34-36.
15. Huffman KM, Orenduff MC, Samsa GP, et al. Dietary carbohydrate intake and high-sensitivity C-reactive protein in at-risk women and men. Am Heart J 2007; 154:962-968.
16. van Oostrom AJ, Sijmonsma TP, Verseyden C, et al. Postprandial recruitment of neutrophils may contribute to endothelial dysfunction. J Lipid Res 2003; 44:576-583.
17. Napolitano M, Bravo E. Lipid metabolism and TNF-alpha secretion in response to dietary sterols in human monocyte derived macrophages. Eur J Clin Invest 2005; 35:482-490.
18. Luu NT, Madden J, Calder PC, et al. Dietary supplementation with fish oil modifies the ability of human monocytes to induce an inflammatory response. J Nutr 2007; 137:2769-2774.
19. Alipour A, van Oostrom AJ, Izraeljan A, et al. Leukocyte activation by triglyceride-rich lipoproteine. Arterioscler Thromb Vase Biol 2008; 28:792-797.
20. Poppitt SD, Keogh GF, Lithander FE, et al. Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition 2008; 4:322-329. A well designed study on the acute postprandial response of several circulating markers of inflammation to high-fat meals (high or low ratio of saturated : unsaturated fatty acids). The authors were unable to document any postprandial change.
21. Calder PC. Polyunsaturated fatty acids and inflammation. Biochem Soc Trans 2005; 33:423-427.
22. Bogani P, Galli C, Villa M, Visioli F. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. Atherosclerosis 2007; 190:181 -186.
23. Pacheco YM, Lopez S, Bermudez B, etal. A meal rich in oleic acid beneficially modulates postprandial sICAM-1 and sVCAM-1 in normotensive and hypertensive hypertnglyceridemic subjects. J Nutr Biochem 2008; 19:200-205. High-fat meals produced an elevation of the circulating levels of adhesion molecules in hypertnglyceridemic patients 8 h postprandially.
24. Calder PC. Immunomodulation by omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids 2007; 77:327-335.
25. Calder PC, Deckelbaum RJ. Omega-3 fatty acids: time to get the messages rightl Curr Opin Clin Nutr Metab Care 2008; 11:91 -93.
26. Devaraj S, Swarbrick MM, Singh U, et al. CRP and adiponectin and its oligomers in the metabolic syndrome: evaluation of new laboratory-based biomarkers. Am J Clin Pathol 2008; 129:815-822.
27. Carroll MF, Schade DS. Timing of antioxidant vitamin ingestion alters postprandial pro-atherogenic serum markers. Circulation 2003; 108:24-31.
28. Assaloni R, Da Ros R, Quagliaro L, et al. Effects of S21403 (mitiglinide) on postprandial generation of oxidative stress and inflammation in type 2 diabetic patients. Diabetologia 2005; 48:1919-1924.
29. Corpeleijn E, Saris WH, Jansen EH, et al. Postprandial interleukin-6 release from skeletal muscle in men with impaired glucose tolerance can be reduced by weight loss. J Clin Endocrinol Metab 2005; 90:5819-5824.
30. Campbell CG, Brown BD, Dufner D, Thorland WG. Effects of soy or milk protein during a high-fat feeding challenge on oxidative stress, inflammation, and lipids in healthy men. Lipids 2006; 41:257-265.
31. Jiao P, Chen Q, Shah S, et al. Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of NF-(kappa) B and JNK pathways. Diabetes 2008 Oct 3. [Epub ahead of print.]
32. Bang HO, Dyerberg J. Lipid metabolism and ischemic heart disease in Greenland Eskimos. In: Draper H, editor. Advances in nutrition research. New York: Plenum Press; 1980. pp. 1-22.
33. GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E in 11,324 patients with myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 1999; 354:447-455.
34. Krauss RM, Eckel RH, Howard B, et al. AHA dietary guidelines. Revision 2000: a statement for Healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation 2000; 102:2284-2299.
35. Kris-Etherton PM, Harris WS, Appel LJ. Fish consumption, fish oil, omega-3 fatty acids and cardiovascular disease. Circulation 2002; 106: 274-357.
36. Tsatsanis C, Androulidaki A, Venihaki M, Margioris AN. Signalling networks regulating cyclooxygenase-2. Int J Biochem Cell Biol 2006; 38:1654-1661.
37. Wang L, Lim EJ, Toborek M, Hennig B. The role of fatty acids and caveolin-1 in tumor necrosis factor alpha-induced endothelial cell activation. Metabolism 2008; 57:1328-1339.
38. Schmilz G, Ecker J. The opposing effects of n-3 and n-6 fatty acids. Prog Lipid Res 2008; 47:147-155.
39. Zhao G, Etherton TD, Martin KR, et al. Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects. Am J Clin Nutr 2007; 85:385-391.
40. Paschos GK, Rallidis LS, Liakos GK, et al. Background diet influences the anti-inflammatory effect of alpha-linolenic acid in dyslipidaemic subjects. Br J Nutr 2004; 92:649-655.
41. Niu K, Hozawa A, Kuriyama S, et al. Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine products. Am J Clin Nutr 2006; 84:223-229.
42. Murphy KJ, Meyer BJ, Mori TA, et al. Impact of foods enriched with n-3 long-chain polyunsaturated fatty acids on erythrocyte n-3 levels and cardiovascular risk factors. Br J Nutr 2007; 97:593-595. Overweight volunteers on a 6-month n-3-enriched diet had the n-3 PUFA of their erythrocytes rise by 35-50%, a finding positively associated with arterial compliance and negatively with serum CRP and urinary 11 -dehydro-TXB2 excretion (main enzymatic metabolite of thromboxane A2, an eicosanoid produced within the platelets by thromboxane-A synthase from the endoperoxides that are produced by cyclooxygenase from arachidonic acid; a powerful vasoconstrictor and hypertensive agent that facilitates platelet aggregation).
43. Madsen T, Christensen JH, Blom M, Schmidt EB. The effect of dietary n-3 fatty acids on serum concentrations of C-reactive protein: a dose-response study. Br J Nutr 2003; 89:517-522.
44. Fredrikson GN, Hedblad B, Nilsson JA, et al. Association between diet, lifestyle, metabolic cardiovascular risk factors, and plasma C-reactive protein levels. Metabolism 2005; 54:1266-1267.
45. Madsen T, Schmidt EB, Christensen JH. The effect of n-3 fatty acids on C-reactive protein levels in patients with chronic renal failure. J Ren Nutr 2007; 17:258-263.
46. Madsen T, Christensen JH, Schmidt EB. C-reactive protein and n-3 fatty acids in patients with a previous myocardial Infarction: a placebo-controlled rando-mized study. Eur J Nutr 2007; 46:428-430.
47. Gravanis A, Margioris AN. The corticotropin-releasing factor (CRF) family of neuropeptides in inflammation: potential therapeutic applications. Curr Med Chem 2005; 12:1503-1512.
48. Elenkov IJ, Chrousos GP. Stress system - organization, physiology and immunoregulation. Neuroimmunomodulation 2006; 13:257-267.
49. Tsigos C, Chrousos GP. Stress, obesity, and the metabolic syndrome: soul and metabolism. Ann N Y Acad Sci 2006; 1083:77-110.