Quantitative structure-activity relationship models with receptor-dependent descriptors for predicting peroxisome proliferator-activated receptor activities of thiazolidinedione and oxazolidinedione derivatives

Chemical Biology and Drug Design

Volumn 73, Issue 4, 2009, Pages 428-441

  Lather, Viney ^a   Kairys, Visvaldas ^a   Fernandes, Miguel X ^a  

^a Centro de Quimica da Madeira   (Portugal)

Author keywords

Multiple linear regression; Peroxisome proliferator activated receptor; Quantitative structure activity relationship

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; LIGAND; OXAZOLIDINEDIONE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; MOLECULAR MODEL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY; STRUCTURE ANALYSIS;

BINDING SITES; DRUG DESIGN; HUMANS; LIGANDS; LINEAR MODELS; MODELS, MOLECULAR; OXAZOLES; PPAR ALPHA; PPAR GAMMA; PROTEIN BINDING; PROTEIN ISOFORMS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINEDIONES;

EID: 61949250262     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00788.x     Document Type: Article

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