-
1
-
-
24944519346
-
Impaired insulin sensitivity as an independent risk factor for mortality in patients with stable chronic heart failure
-
Doehner W, Rauchhaus M, Ponikowski P, Godsland IF, von Haehling S, Okonko DO, Leyva F, Proudler AJ, Coats AJ, Anker SD. Impaired insulin sensitivity as an independent risk factor for mortality in patients with stable chronic heart failure. J Am Coll Cardiol. 2005;46:1019-1026.
-
(2005)
J Am Coll Cardiol.
, vol.46
, pp. 1019-1026
-
-
Doehner, W.1
Rauchhaus, M.2
Ponikowski, P.3
Godsland, I.F.4
Von Haehling, S.5
Okonko, D.O.6
Leyva, F.7
Proudler, A.J.8
Coats, A.J.9
Anker, S.D.10
-
2
-
-
0037046203
-
Adaptation and maladaptation of the heart in diabetes: Part I. General concepts
-
DOI 10.1161/01.CIR.0000012466.50373.E8
-
Taegtmeyer H, McNulty P, Young ME. Adaptation and maladaptation of the heart in diabetes. Part I: general concepts. Circulation. 2002;105: 1727-1733. (Pubitemid 34298619)
-
(2002)
Circulation
, vol.105
, Issue.14
, pp. 1727-1733
-
-
Taegtmeyer, H.1
McNulty, P.2
Young, M.E.3
-
3
-
-
33847080728
-
AMP-activated protein kinase in metabolic control and insulin signaling
-
Towler MC, Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res. 2007;100:328-341.
-
(2007)
Circ Res.
, vol.100
, pp. 328-341
-
-
Towler, M.C.1
Hardie, D.G.2
-
4
-
-
33947526130
-
AMP-activated protein kinase in the heart: Role during health and disease
-
Arad M, Seidman CE, Seidman JG. AMP-activated protein kinase in the heart: role during health and disease. Circ Res. 2007;100:474-488.
-
(2007)
Circ Res.
, vol.100
, pp. 474-488
-
-
Arad, M.1
Seidman, C.E.2
Seidman, J.G.3
-
5
-
-
61949300140
-
Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure
-
Gundewar S, Calvert JW, Jha S, Toedt-Pingel I, Ji SY, Nunez D, Ram-achandran A, Anaya-Cisneros M, Tian R, Lefer DJ. Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure. Circ Res. 2009;104:403-411.
-
(2009)
Circ Res.
, vol.104
, pp. 403-411
-
-
Gundewar, S.1
Calvert, J.W.2
Jha, S.3
Toedt-Pingel, I.4
Ji, S.Y.5
Nunez, D.6
Ram-Achandran, A.7
Anaya-Cisneros, M.8
Tian, R.9
Lefer, D.J.10
-
6
-
-
40949087724
-
Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling
-
Calvert JW, Gundewar S, Jha S, Greer JJ, Bestermann WH, Tian R, Lefer DJ. Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling. Diabetes. 2008;57: 696-705.
-
(2008)
Diabetes
, vol.57
, pp. 696-705
-
-
Calvert, J.W.1
Gundewar, S.2
Jha, S.3
Greer, J.J.4
Bestermann, W.H.5
Tian, R.6
Lefer, D.J.7
-
7
-
-
0034614420
-
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex i
-
El-Mir M-Y, Nogueira V, Fontaine E, Averet N, Rigoulet M, Leverve X. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem. 2000;275:223-228.
-
(2000)
J Biol Chem.
, vol.275
, pp. 223-228
-
-
El-Mir, M.-Y.1
Nogueira, V.2
Fontaine, E.3
Averet, N.4
Rigoulet, M.5
Leverve, X.6
-
8
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J. 2000;348:607-614.
-
(2000)
Biochem J.
, vol.348
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
9
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
Hawley SA, Gadalla AE, Olsen GS, Hardie DG. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes. 2002;51: 2420-2425.
-
(2002)
Diabetes
, vol.51
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
10
-
-
21144446106
-
PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis
-
Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semen-kovich CF, Kelly DP. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol. 2005;3:e101.
-
(2005)
PLoS Biol.
, vol.3
-
-
Leone, T.C.1
Lehman, J.J.2
Finck, B.N.3
Schaeffer, P.J.4
Wende, A.R.5
Boudina, S.6
Courtois, M.7
Wozniak, D.F.8
Sambandam, N.9
Bernal-Mizrachi, C.10
Chen, Z.11
Holloszy, J.O.12
Medeiros, D.M.13
Schmidt, R.E.14
Saffitz, J.E.15
Abel, E.D.16
Semen-Kovich, C.F.17
Kelly, D.P.18
-
11
-
-
33745627066
-
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha
-
Arany Z, Novikov M, Chin S, Ma Y, Rosenzweig A, Spiegelman BM. Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-gamma coactivator 1alpha. Proc Natl Acad Sci U S A. 2006;103:10086-10091.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, pp. 10086-10091
-
-
Arany, Z.1
Novikov, M.2
Chin, S.3
Ma, Y.4
Rosenzweig, A.5
Spiegelman, B.M.6
-
12
-
-
34248151855
-
Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage
-
Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, Tian R. Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007;117:1432-1439.
-
(2007)
J Clin Invest.
, vol.117
, pp. 1432-1439
-
-
Luptak, I.1
Shen, M.2
He, H.3
Hirshman, M.F.4
Musi, N.5
Goodyear, L.J.6
Yan, J.7
Wakimoto, H.8
Morita, H.9
Arad, M.10
Seidman, C.E.11
Seidman, J.G.12
Ingwall, J.S.13
Balschi, J.A.14
Tian, R.15
-
13
-
-
40649104960
-
Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage
-
Ofir M, Arad M, Porat E, Freimark D, Chepurko Y, Vidne BA, Seidman CE, Seidman JG, Kemp BE, Hochhauser E. Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage. Biochem Pharmacol. 2008;75:1482-1491.
-
(2008)
Biochem Pharmacol.
, vol.75
, pp. 1482-1491
-
-
Ofir, M.1
Arad, M.2
Porat, E.3
Freimark, D.4
Chepurko, Y.5
Vidne, B.A.6
Seidman, C.E.7
Seidman, J.G.8
Kemp, B.E.9
Hochhauser, E.10
-
14
-
-
29444432915
-
The ubiquitous role of nitric oxide in cardioprotection
-
Jones SP, Bolli R. The ubiquitous role of nitric oxide in cardioprotection. J Mol Cell Cardiol. 2006;40:16-23.
-
(2006)
J Mol Cell Cardiol.
, vol.40
, pp. 16-23
-
-
Jones, S.P.1
Bolli, R.2
-
15
-
-
12844265354
-
Myocardial ischemia differentially regulates LKB1 and an alternate 5-AMP-activated protein kinase kinase
-
Altarejos JY, Taniguchi M, Clanachan AS, Lopaschuk GD. Myocardial ischemia differentially regulates LKB1 and an alternate 5--AMP-activated protein kinase kinase. J Biol Chem. 2005;280:183-190.
-
(2005)
J Biol Chem.
, vol.280
, pp. 183-190
-
-
Altarejos, J.Y.1
Taniguchi, M.2
Clanachan, A.S.3
Lopaschuk, G.D.4
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