The Lymphotoxin LTα1β2 Controls Postnatal and Adult Spleen Marginal Sinus Vascular Structure and Function

Immunity

Volumn 30, Issue 3, 2009, Pages 408-420

  Zindl, Carlene L ^a,b   Kim, Tea Hyun ^b   Zeng, Meiqin ^b   Archambault, Angela S ^a   Grayson, Mitchell H ^a   Choi, Kyunghee ^a   Schreiber, Robert D ^a   Chaplin, David D ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

CELLIMMUNO

Indexed keywords

LYMPHOTOXIN ALPHA BETA; LYMPHOTOXIN BETA RECEPTOR; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; SMOOTH MUSCLE ACTIN; VASCULOTROPIN RECEPTOR 2; BACTERIAL ANTIGEN; CADHERIN; CD31 ANTIGEN; CELL ADHESION MOLECULE; LEUKOCYTE ANTIGEN; MADCAM1 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SINUS VENOSUS; SPLEEN; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, CD; ANTIGENS, CD31; CADHERINS; CELL ADHESION MOLECULES; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN;

EID: 61949160618     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2009.01.010     Document Type: Article

References (48)

1. Balazs M., Horvath G., Grama L., and Balogh P. Phenotypic identification and development of distinct microvascular compartments in the postnatal mouse spleen. Cell. Immunol. 212 (2001) 126-137
2. Balazs M., Martin F., Zhou T., and Kearney J. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 17 (2002) 341-352
3. Balogh P., Balazs M., Czompoly T., Weih D.S., Arnold H.H., and Weih F. Distinct roles of lymphotoxin-beta signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen. Cell Tissue Res. 328 (2007) 473-486
4. Banks T.A., Rouse B.T., Kerley M.K., Blair P.J., Godfrey V.L., Kuklin N.A., Bouley D.M., Thomas J., Kanangat S., and Mucenski M.L. Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness. J. Immunol. 155 (1995) 1685-1693
5. Bohnsack J.F., and Brown E.J. The role of the spleen in resistance to infection. Annu. Rev. Med. 37 (1986) 49-59
6. Browning J.L., Dougas I., Ngam-ek A., Bourdon P.R., Ehrenfels B.N., Miatkowski K., Zafari M., Yampaglia A.M., Lawton P., Meier W., et al. Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors. J. Immunol. 154 (1995) 33-46
7. Browning J.L., Sizing I.D., Lawton P., Bourdon P.R., Rennert P.D., Majeau G.R., Ambrose C.M., Hession C., Miatkowski K., Griffiths D.A., et al. Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes. J. Immunol. 159 (1997) 3288-3298
8. Bullard D.C., Hu X., Schoeb T.R., Collins R.G., Beaudet A.L., and Barnum S.R. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis. J. Immunol. 178 (2007) 851-857
9. De Togni P., Goellner J., Ruddle N.H., Streeter P.R., Fick A., Mariathasan S., Smith S.C., Carlson R., Shornick L.P., Strauss-Schoenberger J., et al. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264 (1994) 703-707
10. Dejardin E., Droin N.M., Delhase M., Haas E., Cao Y., Makris C., Li Z.W., Karin M., Ware C.F., and Green D.R. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 17 (2002) 525-535
11. Eberl G., Marmon S., Sunshine M.J., Rennert P.D., Choi Y., and Littman D.R. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5 (2004) 64-73
12. Ejstrud P., Kristensen B., Hansen J.B., Madsen K.M., Schonheyder H.C., and Sorensen H.T. Risk and patterns of bacteraemia after splenectomy: A population-based study. Scand. J. Infect. Dis. 32 (2000) 521-525
13. Ettinger R., Browning J.L., Michie S.A., van Ewijk W., and McDevitt H.O. Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein. Proc. Natl. Acad. Sci. USA 93 (1996) 13102-13107
14. Fu Y.X., and Chaplin D.D. Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol. 17 (1999) 399-433
15. Futterer A., Mink K., Luz A., Kosco-Vilbois M.H., and Pfeffer K. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9 (1998) 59-70
16. Gale N.W., Baluk P., Pan L., Kwan M., Holash J., DeChiara T.M., McDonald D.M., and Yancopoulos G.D. Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells. Dev. Biol. 230 (2001) 151-160
17. Girkontaite I., Sakk V., Wagner M., Borggrefe T., Tedford K., Chun J., and Fischer K.D. The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization. J. Exp. Med. 200 (2004) 1491-1501
18. Grayson M.H., Chaplin D.D., Karl I.E., and Hotchkiss R.S. Confocal fluorescent intravital microscopy of the murine spleen. J. Immunol. Methods 256 (2001) 55-63
19. Karlsson M.C., Guinamard R., Bolland S., Sankala M., Steinman R.M., and Ravetch J.V. Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone. J. Exp. Med. 198 (2003) 333-340
20. Koike R., Nishimura T., Yasumizu R., Tanaka H., Hataba Y., Hataba Y., Watanabe T., Miyawaki S., and Miyasaka M. The splenic marginal zone is absent in alymphoplastic aly mutant mice. Eur. J. Immunol. 26 (1996) 669-675
21. Koni P.A., Sacca R., Lawton P., Browning J.L., Ruddle N.H., and Flavell R.A. Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice. Immunity 6 (1997) 491-500
22. Kraal G. Cells in the marginal zone of the spleen. Int. Rev. Cytol. 132 (1992) 31-74
23. Kraal G., and Janse M. Marginal metallophilic cells of the mouse spleen identified by a monoclonal antibody. Immunology 58 (1986) 665-669
24. Kraal G., and Mebius R. New insights into the cell biology of the marginal zone of the spleen. Int. Rev. Cytol. 250 (2006) 175-215
25. Kraal G., Schornagel K., Streeter P.R., Holzmann B., and Butcher E.C. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Pathol. 147 (1995) 763-771
26. Lo J.C., Basak S., James E.S., Quiambo R.S., Kinsella M.C., Alegre M.L., Weih F., Franzoso G., Hoffmann A., and Fu Y.X. Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues. Blood 107 (2006) 1048-1055
27. Lu T.T., and Cyster J.G. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 297 (2002) 409-412
28. Mackay F., Majeau G.R., Lawton P., Hochman P.S., and Browning J.L. Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice. Eur. J. Immunol. 27 (1997) 2033-2042
29. Mandik-Nayak L., Huang G., Sheehan K.C., Erikson J., and Chaplin D.D. Signaling through TNF receptor p55 in TNF-alpha-deficient mice alters the CXCL13/CCL19/CCL21 ratio in the spleen and induces maturation and migration of anergic B cells into the B cell follicle. J. Immunol. 167 (2001) 1920-1928
30. Matsushima A., Kaisho T., Rennert P.D., Nakano H., Kurosawa K., Uchida D., Takeda K., Akira S., and Matsumoto M. Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I. J. Exp. Med. 193 (2001) 631-636
31. Mebius R.E., and Kraal G. Structure and function of the spleen. Nat. Rev. Immunol. 5 (2005) 606-616
32. Mebius R.E., Streeter P.R., Michie S., Butcher E.C., and Weissman I.L. A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93 (1996) 11019-11024
33. Mebius R.E., Nolte M.A., and Kraal G. Development and function of the splenic marginal zone. Crit. Rev. Immunol. 24 (2004) 449-464
34. Neumann B., Luz A., Pfeffer K., and Holzmann B. Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor. J. Exp. Med. 184 (1996) 259-264
35. Ngo V.N., Korner H., Gunn M.D., Schmidt K.N., Riminton D.S., Cooper M.D., Browning J.L., Sedgwick J.D., and Cyster J.G. Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189 (1999) 403-412
36. Pasparakis M., Alexopoulou L., Episkopou V., and Kollias G. Immune and inflammatory responses in TNF alpha-deficient mice: A critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J. Exp. Med. 184 (1996) 1397-1411
37. Pasparakis M., Alexopoulou L., Grell M., Pfizenmaier K., Bluethmann H., and Kollias G. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor. Proc. Natl. Acad. Sci. USA 94 (1997) 6319-6323
38. Pasparakis M., Kousteni S., Peschon J., and Kollias G. Tumor necrosis factor and the p55TNF receptor are required for optimal development of the marginal sinus and for migration of follicular dendritic cell precursors into splenic follicles. Cell. Immunol. 201 (2000) 33-41
39. Rennert P.D., Browning J.L., Mebius R., Mackay F., and Hochman P.S. Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs. J. Exp. Med. 184 (1996) 1999-2006
40. Rennert P.D., James D., Mackay F., Browning J.L., and Hochman P.S. Lymph node genesis is induced by signaling through the lymphotoxin beta receptor. Immunity 9 (1998) 71-79
41. Schmidt E.E., MacDonald I.C., and Groom A.C. Microcirculation in mouse spleen (nonsinusal) studied by means of corrosion casts. J. Morphol. 186 (1985) 17-29
42. Shin D., Garcia-Cardena G., Hayashi S., Gerety S., Asahara T., Stavrakis G., Isner J., Folkman J., Gimbrone Jr. M.A., and Anderson D.J. Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. Dev. Biol. 230 (2001) 139-150
43. Smith C., Andreakos E., Crawley J.B., Brennan F.M., Feldmann M., and Foxwell B.M. NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts. J. Immunol. 167 (2001) 5895-5903
44. Steiniger B., and Barth P. Microanatomy and function of the spleen. Adv. Anat. Embryol. Cell Biol. 151 (2000) III-IX, 1-101
45. Waghorn D.J. Overwhelming infection in asplenic patients: Current best practice preventive measures are not being followed. J. Clin. Pathol. 54 (2001) 214-218
46. Wang H.U., Chen Z.F., and Anderson D.J. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93 (1998) 741-753
47. Weih D.S., Yilmaz Z.B., and Weih F. Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines. J. Immunol. 167 (2001) 1909-1919
48. Yin L., Wu L., Wesche H., Arthur C.D., White J.M., Goeddel D.V., and Schreiber R.D. Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. Science 291 (2001) 2162-2165