Distinct response in maintenance of human naive and memory B cells via IL-21 receptor and TCL1/Akt pathways

Cellular Immunology

Volumn 256, Issue 1-2, 2009, Pages 56-63

  Nagumo, Haruo ^a,b   Abe, Jun ^c   Kano, Hirotsugu ^c   Taki, Shinsuke ^a   Yamazaki, Kazuko ^a   Yamazaki, Takashi ^b   Kobayashi, Norimoto ^b   Koike, Kenichi ^b   Sugane, Kazuo ^a   Saito, Hirohisa ^c   Agematsu, Kazunaga ^a,b  

^a SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Akt; IL 21 receptor; Lifespan; Maintenance; Memory B cells; Na ve B cells; TCL1

Indexed keywords

CD40 ANTIGEN; GENE PRODUCT; IMMUNOGLOBULIN ANTIBODY; INTERLEUKIN 21 RECEPTOR; PROTEIN KINASE B; PROTEIN TCL1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CPG ISLAND; ENZYME PHOSPHORYLATION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE SUBPOPULATION; MEMORY CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; STAPHYLOCOCCUS AUREUS; TCL1 GENE;

ADULT; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; BASE SEQUENCE; CELL SURVIVAL; DNA PRIMERS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, IGG; RECEPTORS, INTERLEUKIN-21; SIGNAL TRANSDUCTION; TRANSFECTION;

STAPHYLOCOCCUS AUREUS;

EID: 61849184052     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2009.01.005     Document Type: Article

References (48)

1. Jackson S.M., Wilson P.C., James J.A., and Capra J.D. Human B cell subsets. Adv. Immunol. 98 (2008) 151-224
2. LeBien T.W., and Tedder T.F. B lymphocytes: how they develop and function. Blood 112 (2008) 1570-1580
3. Agematsu K., Hokibara S., Nagumo H., and Komiyama A. CD27: a memory B-cell marker. Immunol. Today 21 (2000) 204-206
4. Fecteau J.F., and Neron S. CD40 stimulation of human peripheral B lymphocytes: distinct response from naive and memory cells. J. Immunol. 171 (2003) 4621-4629
5. Bernasconi N.L., Traggiai E., and Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298 (2002) 2199-2202
6. Klein U., Tu Y., Stolovitzky G.A., Keller J.L., Haddad Jr. J., Miljkovic V., Cattoretti G., Califano A., and Dalla-Favera R. Transcriptional analysis of the B cell germinal center reaction. Proc. Natl. Acad. Sci. USA 100 (2003) 2639-2644
7. Parrish-Novak J., Dillon S.R., Nelson A., Hammond A., Sprecher C., Gross J.A., Johnston J., Madden K., Xu W., West J., Schrader S., Burkhead S., Heipel M., Brandt C., Kuijper J.L., Kramer J., Conklin D., Presnell S.R., Berry J., Shiota F., Bort S., Hambly K., Mudri S., Clegg C., Moore M., Grant F.J., Lofton-Day C., Gilbert T., Rayond F., Ching A., Yao L., Smith D., Webster P., Whitmore T., Maurer M., Kaushansky K., Holly R.D., and Foster D. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 408 (2000) 57-63
8. Coquet J.M., Kyparissoudis K., Pellicci D.G., Besra G., Berzins S.P., Smyth M.J., and Godfrey D.I. IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production. J. Immunol. 178 (2007) 2827-2834
9. Brandt K., Bulfone-Paus S., Foster D.C., and Ruckert R. Interleukin-21 inhibits dendritic cell activation and maturation. Blood 102 (2003) 4090-4098
10. Habib T., Senadheera S., Weinberg K., and Kaushansky K. The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3. Biochemistry 41 (2002) 8725-8731
11. Mehta D.S., Wurster A.L., Whitters M.J., Young D.A., Collins M., and Grusby M.J. IL-21 induces the apoptosis of resting and activated primary B cells. J. Immunol. 170 (2003) 4111-4118
12. Jin H., Carrio R., Yu A., and Malek T.R. Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis. J. Immunol. 173 (2004) 657-665
13. Zeng R., Spolski R., Casas E., Zhu W., Levy D.E., and Leonard W.J. The molecular basis of IL-21-mediated proliferation. Blood 109 (2007) 4135-4142
14. Pekarsky Y., Hallas C., and Croce C.M. Molecular basis of mature T-cell leukemia. JAMA 286 (2001) 2308-2314
15. Said J.W., Hoyer K.K., French S.W., Rosenfelt L., Garcia-Lloret M., Koh P.J., Cheng T.C., Sulur G.G., Pinkus G.S., Kuehl W.M., Rawlings D.J., Wall R., and Teitell M.A. TCL1 oncogene expression in B cell subsets from lymphoid hyperplasia and distinct classes of B cell lymphoma. Lab. Invest. 81 (2001) 555-564
16. Teitell M., Damore M.A., Sulur G.G., Turner D.E., Stern M.H., Said J.W., Denny C.T., and Wall R. TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues. Proc. Natl. Acad. Sci. USA 96 (1999) 9809-9814
17. Nakayama I., Murao S., Kitazawa S., Azumi A., Yamamoto M., and Maeda S. Activation of the TCL1 protein in B cell lymphomas. Pathol. Int. 50 (2000) 191-199
18. Narducci M.G., Pescarmona E., Lazzeri C., Signoretti S., Lavinia A.M., Remotti D., Scala E., Baroni C.D., Stoppacciaro A., Croce C.M., and Russo G. Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues. Cancer Res. 60 (2000) 2095-2100
19. Gold M.R. Akt is TCL-ish: implications for B-cell lymphoma. Trends Immunol. 24 (2003) 104-108
20. Laine J., Kunstle G., Obata T., Sha M., and Noguchi M. The protooncogene TCL1 is an Akt kinase coactivator. Mol. Cell 6 (2000) 395-407
21. Pekarsky Y., Koval A., Hallas C., Bichi R., Tresini M., Malstrom S., Russo G., Tsichlis P., and Croce C.M. Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc. Natl. Acad. Sci. USA 97 (2000) 3028-3033
22. Kunstle G., Laine J., Pierron G., Kagami Si S., Nakajima H., Hoh F., Roumestand C., Stern M.H., and Noguchi M. Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1. Mol. Cell. Biol. 22 (2002) 1513-1525
23. Peltz G.A., Trounstine M.L., and Moore K.W. Cloned and expressed human Fc receptor for IgG mediates anti-CD3-dependent lymphoproliferation. J. Immunol. 141 (1988) 1891-1896
24. Karasuyama H., Kudo A., and Melchers F. The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain. J. Exp. Med. 172 (1990) 969-972
25. Nagumo H., Agematsu K., Kobayashi N., Shinozaki K., Hokibara S., Nagase H., Takamoto M., Yasui K., Sugane K., and Komiyama A. The different process of class switching and somatic hypermutation; a novel analysis by CD27(-) naive B cells. Blood 99 (2002) 567-575
26. Okumura S., Kashiwakura J., Tomita H., Matsumoto K., Nakajima T., Saito H., and Okayama Y. Identification of specific gene expression profiles in human mast cells mediated by Toll-like receptor 4 and FcepsilonRI. Blood 102 (2003) 2547-2554
27. Good K.L., and Tangye S.G. Decreased expression of Kruppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses. Proc. Natl. Acad. Sci. USA 104 (2007) 13420-13425
28. Kharas M.G., Yusuf I., Scarfone V.M., Yang V.W., Segre J.A., Huettner C.S., and Fruman D.A. KLF4 suppresses transformation of pre-B cells by ABL oncogenes. Blood 109 (2007) 747-755
29. Kandel E.S., and Hay N. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp. Cell. Res. 253 (1999) 210-229
30. Scheid M.P., and Woodgett J.R. PKB/AKT: functional insights from genetic models. Nat. Rev. Mol. Cell. Biol. 2 (2001) 760-768
31. Agenes F., Rosado M.M., and Freitas A.A. Peripheral B cell survival. Cell. Mol. Life Sci. 57 (2000) 1220-1228
32. Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., and Honma K. Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature 419 (2002) 841-844
33. Takahashi K., and Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006) 663-676
34. Okita K., Ichisaka T., and Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 448 (2007) 313-317
35. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., and Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007) 861-872
36. Ozaki K., Spolski R., Feng C.G., Qi C.F., Cheng J., Sher A., Morse III H.C., Liu C., Schwartzberg P.L., and Leonard W.J. A critical role for IL-21 in regulating immunoglobulin production. Science 298 (2002) 1630-1634
37. Chtanova T., Tangye S.G., Newton R., Frank N., Hodge M.R., Rolph M.S., and Mackay C.R. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J. Immunol. 173 (2004) 68-78
38. Mitoma H., Horiuchi T., Kimoto Y., Tsukamoto H., Uchino A., Tamimoto Y., Miyagi Y., and Harada M. Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus. Int. J. Mol. Med. 16 (2005) 609-615
39. Good K.L., Bryant V.L., and Tangye S.G. Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J. Immunol. 177 (2006) 5236-5247
40. Ettinger R., Sims G.P., Fairhurst A.M., Robbins R., da Silva Y.S., Spolski R., Leonard W.J., and Lipsky P.E. IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J. Immunol. 175 (2005) 7867-7879
41. Ettinger R., Sims G.P., Robbins R., Withers D., Fischer R.T., Grammer A.C., Kuchen S., and Lipsky P.E. IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J. Immunol. 178 (2007) 2872-2882
42. Kovanen P.E., and Leonard W.J. Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol. Rev. 202 (2004) 67-83
43. Hoyer K.K., French S.W., Turner D.E., Nguyen M.T., Renard M., Malone C.S., Knoetig S., Qi C.F., Su T.T., Cheroutre H., Wall R., Rawlings D.J., Morse III H.C., and Teitell M.A. Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma. Proc. Natl. Acad. Sci. USA 99 (2002) 14392-14397
44. Bichi R., Shinton S.A., Martin E.S., Koval A., Calin G.A., Cesari R., Russo G., Hardy R.R., and Croce C.M. Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc. Natl. Acad. Sci. USA 99 (2002) 6955-6960
45. Pogue S.L., Kurosaki T., Bolen J., and Herbst R. B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase. J. Immunol. 165 (2000) 1300-1306
46. Narducci M.G., Fiorenza M.T., Kang S.M., Bevilacqua A., Di Giacomo M., Remotti D., Picchio M.C., Fidanza V., Cooper M.D., Croce C.M., Mangia F., and Russo G. TCL1 participates in early embryonic development and is overexpressed in human seminomas. Proc. Natl. Acad. Sci. USA 99 (2002) 11712-11717
47. Niwa H. How is pluripotency determined and maintained?. Development 134 (2007) 635-646
48. Patke A., Mecklenbrauker I., Erdjument-Bromage H., Tempst P., and Tarakhovsky A. BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism. J. Exp. Med. 203 (2006) 2551-2562