An organophosphorus hapten used in the preparation of monoclonal antibody and as an active immunization vaccine in the detoxication of soman poisoning

Toxicology Letters

Volumn 187, Issue 1, 2009, Pages 45-51

  Jia, Peiyuan ^a   Wang, Yuxia ^a   Yu, Ming ^b   Wu, Junhua ^a   Yang, Rifang ^a   Zhao, Yu ^a   Zhou, Lijun ^c  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c NAVY GENERAL HOSPITAL   (China)

Author keywords

Hapten; Monoclonal antibody; Organophosphorus; Soman

Indexed keywords

ACETYLCHOLINESTERASE; GAMMA HYDROXYPHOSPHONATE ESTER HAPTEN BOVINE SERUM ALBUMIN CONJUGATE; GAMMA HYDROXYPHOSPHONATE ESTER HAPTEN HEMOCYANIN CONJUGATE; HAPTEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2C10; MONOCLONAL ANTIBODY 3B9; MONOCLONAL ANTIBODY 3C11; MONOCLONAL ANTIBODY 3G1; SOMAN; SOMAN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DRUG CONJUGATION; DRUG POTENCY; ENZYME INHIBITION; FEMALE; IC 50; IMMUNIZATION; INTOXICATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINE PRODUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CATTLE; CHOLINESTERASE INHIBITORS; FEMALE; HAPTENS; HEMOCYANIN; MICE; MICE, INBRED BALB C; ORGANOPHOSPHORUS COMPOUNDS; SERUM ALBUMIN, BOVINE; SOMAN; VACCINATION; VACCINES;

BOVINAE; LIMULUS POLYPHEMUS; MUS;

EID: 61849156837     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.01.029     Document Type: Article

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