Protein phosphatase 2A inhibition and circumvention of cisplatin cross-resistance by novel TCM-platinum anticancer agents containing demethylcantharidin

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 17, 2004, Pages 4565-4573

  To, Kenneth K W ^a   Wang, Xinning ^a   Yu, Chun Wing ^a   Ho, Yee Ping ^a   Au Yeung, Steve C F ^b  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Cisplatin resistance; Demethylcantharidin; Nucleotide excision repair; Protein phosphatase inhibition

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; NORCANTHARIDIN; OXALIPLATIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PLATINUM DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; CROSS REACTION; DNA REPAIR; DRUG POTENCY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; STEREOCHEMISTRY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CANTHARIDIN; CISPLATIN; CROSS-LINKING REAGENTS; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; MEDICINE, CHINESE TRADITIONAL; ORGANOPLATINUM COMPOUNDS; PHOSPHOPROTEIN PHOSPHATASE; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 3843050236     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.07.009     Document Type: Article

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