Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism

British Journal of Cancer

Volumn 100, Issue 5, 2009, Pages 723-731

  Bourre L ^a   Giuntini, F ^b   Eggleston, I M ^b   Wilson, M ^c   MacRobert, A J ^a,d  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b University of Bath   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Acylpeptide hydrolase (ACPH, EC 3.4.19.1); ALA derivatives; Aminolaevulinic acid; Photodynamic therapy; Protoporphyrin IX; siRNA silencing

Indexed keywords

ACYLAMINO ACID RELEASING ENZYME; AMINOLEVULINIC ACID; AMINOLEVULINIC ACID DERIVATIVE; PEPTIDE DERIVATIVE; PROTOPORPHYRIN; RNA; SERINE PROTEINASE INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CYTOTOXICITY; DRUG EFFICACY; DRUG STRUCTURE; HUMAN; HUMAN CELL; HYDROLYSIS; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINOLEVULINIC ACID; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; GENE KNOCKDOWN TECHNIQUES; INTRACELLULAR SPACE; MICE; MODELS, BIOLOGICAL; PEPTIDE HYDROLASES; PEPTIDES; PRODRUGS; PROTOPORPHYRINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 61749098142     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604928     Document Type: Article

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