In vitro fluorescence, toxicity and phototoxicity induced by 6-aminolevulinic acid (ALA) or ALA-esters

Photochemistry and Photobiology

Volumn 71, Issue 4, 2000, Pages 447-454

  Eléouet, Sabine ^a   Rousset, Nathalie ^a   Carré, Jérôme ^a   Bourré, Ludovic ^a   Vonarx, Veronique ^a   Lajat, Youenn ^a   Beijersbergen Van Henegouwen, Gerard M J ^b,c   Patrice, Thierry ^a  

^a CHU de Nantes   (France)

^b Dept of Medicinal Photochemistry ^*  (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; AMINOLEVULINIC ACID 2 (HYDROXYMETHYL)TETRAHYDROFURANYL ESTER; AMINOLEVULINIC ACID PENTYL ESTER; ESTER DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DRUG EFFECT; DRUG EFFICACY; FLUORESCENCE; GLIOMA CELL; IN VITRO STUDY; INCUBATION TIME; LETHAL DOSE; NONHUMAN; PHOTOTOXICITY;

AMINOLEVULINIC ACID; ANIMALS; ESTERS; FLUORESCENCE; HUMANS; PHOTOSENSITIZING AGENTS; RATS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0034175415     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2000)071<0447:IVFTAP>2.0.CO;2     Document Type: Article

References (32)

1. Kennedy, J. C., R. H. Pottier and D. C. Pross (1990) Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience. J. Photochem. Photobiol. B Biol. 6, 143-148.
2. Cairnduff, F., M. R. Stringer, E. J. Hudson, D. V. Ash and S. B. Brown (1994) Superficial photodynamic therapy with topical 5-aminolevulinic acid for superficial primary and secondary skin cancer. Br. J. Cancer 69, 605-608.
3. Svanberg, K., T. Andersson, D. Killander, I. Wang, U. Stenram, S. Andersson-Engels, R. Berg, J. Johansson and S. Svanberg (1994) Photodynamic therapy of nonmelanoma malignant tumours of the skin using topical δ-amino levulinic acid sensitization and laser irradiation. Br. J. Dermatol. 130, 743-751.
4. Regula, J., A. J. MacRobert, A. Gorchein, G. A. Buonaccorsi, S. M. Thorpe, G. M. Spencer, A. R. W. Hatfield and S. G. Bown (1995) Photosensitisation and photodynamic therapy of oesophageal, duodenal and colorectal tumors using 5 aminolaevulinic acid-induced protoporphyrin IX - a pilot study. Gut 36, 67-75.
5. Kriegmair, M., R. Baumgartner, R. Knuechel, H. Stepp, F. Hofsttadter and A. Hofstetter (1996) Detection of early bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence. J. Urol. 155, 105-110.
6. Fritsch, C., G. Goerz and T. Ruzicka (1998) Photodynamic therapy in dermatology. Arch. Dermatol. 134, 207-214.
7. Eléouet, S., N. Rousset, J. Carré V. Vonarx, C. Vilatte, C. Louët, Y. Lajat and T. Patrice (1999) Heterogeneity of δ-aminolevulinic acid-induced protoporphyrin IX fluorescence in human leukemic lymphocytes and glioma cells. Neurol. Res. (In press)
8. Peng, Q., T. Warloe, K. Berg, J. Moan, M. Kongshaug, K. E. Giercksky and J. M. Nesland (1997) 5-aminolevulinic acid-based photodynamic therapy: clinical research and future challenges. Cancer 79, 2282-2308.
9. Kloek, J., W. Akkermans and G. M. J. Beijersbergen van Henegouwen (1998) Derivatives of 5-aminolevulinic acid for photodynamic therapy (investigations of their enzymatic conversion into protoporphyrin). Photochem. Photobiol. 67, 150-154.
10. Peng, Q., K. Berg, J. Moan, M. Kongshaug and J. M. Nesland (1997) 5-aminolevulinic acid-based photodynamic therapy: principles and experimental research. Photochem. Photobiol. 65, 235-251.
11. Gaullier, J. M., K. Berg, Q. Peng, A. Anholt, P. K. Selbo, L. W. Ma and J. Moan (1997) Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture. Cancer Res. 57, 1481-1486.
12. Peng, Q., T. Warloe, J. Moan, H. Heyerdahl, H. Steen, K. E. Giercksky and J. M. Nesland (1995) ALA derivative-induced protoporphyrin IX build-up and distribution in human nodular basal cell carcinoma. Photochem. Photobiol. 61, [Abstract 82S].
13. Peng, Q., J. Moan, V. Iani, H. B. Steen, A. Bjorseth and J. M. Nesland (1996) Build-up of esterified aminolevulinic-acid-derivative-induced porphyrin fluorescence in normal mouse skin. J. Photochem. Photobiol. B Biol. 34, 95-96.
14. Kloek, J. and G. M. J. Beijersbergen van Henegouwen (1996) Prodrugs of 5-aminolevulinic acid for photodynamic therapy. Photochem. Photobiol. 64, 994-1000.
15. Stummer, W., S. Stocker, S. Wagner, H. Stepp, C. Fritsch, C. Goetz, A. E. Goetz, R. Kiefmann and H. J. Reulen (1998) Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence. Neurosurgery 42, 518-526.
16. Takeya, H. (1992) Preparation of 5-aminolevulinic acid alkyl esters as herbicides. Chem. Abstr. 116, P 189633m.
17. Vonarx-Coinsman, V., M. T. Foultier, L. Xavier de Brito, L. Morlet, A. Gouyette and T. Patrice (1995) HepG2 human hepatocarcinoma cells: an experimental model for photosensitization by endogenous porphyrins. J. Photochem. Photohiol. B Biol. 30, 201-208.
18. Mossmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J. Immunol. Methods 6, 55-63.
19. Fink-Puches, R., A. Hofer, J. Smolle, H. Kerl and P. Wolf (1997) Primary clinical response and long-term follow-up of solar keratoses treated with topically applied 5-aminolevulinic acid irradiation by different wave bands of light. J. Photochem. Photobiol. B Biol. 41, 145-151.
20. Jichlinski, P., M. Forrer, J. Mizeret, T. Glanzmann, D. Braichotte, G. Wagnieres, G. Zimmer, L. Guillou, F. Schmidlin, P. Graber, H. van den Bergh and H. J. Leisinger (1997) Clinical evaluation of a method for detecting superficial surgical transitional cell carcinoma of the bladder by light-induced fluorescence of protoporphyrin IX following the topical application of 5-aminolevulinic acid: preliminary results. Lasers Surg. Med. 20, 402-408.
21. Campbell, D. L., E. F. Gudgin-Dickson, P. G. Forkert, R. H. Pottier and J. C. Kennedy (1996) Detection of early stages of carcinogenesis in adenomas of murine lung by 5-aminolevulinic acid-induced protoporphyrin IX fluorescence. Photochem. Photobiol. 64, 676-682.
22. Davis, R. K., R. Straight and Y. Sun (1997) Intraoperative phototherapy: a comparative study of intravenous and topical photofrin II and aminolevulinic acid. Otolaryngol. Head Neck Surg. 116, 223-227.
23. Dilkes, M. G., M. L. DeJode, Q. Gardiner, G. S. Kenyon and P. McKelvie (1995) Treatment of head and neck cancer with photodynamic therapy: results after one year. J. Laryngol. Otol. 109, 1072-1076.
24. Mlkvy, P., H. Messmann, J. Regula, M. Conio, M. Pauer, C. E. Millson, A. J. MacRobert and S. G. Bown (1995) Sensitization and photodynamic therapy (PDT of gastrointestinal tumors with 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX): a pilot study. Neoplasma 42, 109-113.
25. Gossner, L., M. Stolte, R. Sroka, K. Rick, A. May, E. G. Hahn and C. Ell (1998) Photodynamic ablation of high-grade dysplasia and early cancer Barrett's esophagus by means of 5-aminolevulinic acid. Gastroenterology 114, 448-455.
26. Barr, H., N. A. Shepherd, A. Dix, D. J. Roberts, W. C. Tan and N. Krasner (1996) Eradication of high-grade dysplasia in columnar-lined (Barrett's) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX. Lancet 348, 584-585.
27. Goff, B. A., R. Bachor, N. Kollias and T. Hasan (1992) Effects of photodynamic therapy with topical application of 5-aminolevulinic acid on normal skin of hairless guinea pigs. J. Photochem. Photobiol. B Biol. 15, 239-251.
28. Bech, O., D. Phillips, J. Moan and A. J. MacRobert (1997) A hydroxypyridinone (CP94) enhances protoporphyrin IX formation in 5-aminolevulinic acid treated cells. J. Photochem. Photobiol. B Biol. 41, 136-144.
29. Martin, A., W. D. Tope, J. M. Grevelink, J. C. Starr, J. L. Fewkes, T. J. Flotte, T. F. Deutsch and R. R. Anderson (1995) Lack of selectivity of protoporphyrin IX fluorescence for basal cell carcinoma after topical application of 5-aminolevulinic acid: implications for photodynamic treatment. Arch. Dermatol. Res. 287, 665-674.
30. Washbrook, R. and P. A. Riley (1997) Comparison of δ-aminolevulinic acid and its methyl ester as an inducer of porphyrin synthesis in cultured cells. Br. J. Cancer 75, 1417-1420.
31. Merlin, J. L., S. Azzi, D. Lignon, C. Ramacci, N. Zeghari and F. Guillemin (1992) MTT assays allow quick and reliable measurement of the response of human tumour cells to photodynamic therapy. Eur. J. Cancer 28A, 1452-1458.
32. Foultier, M. T., Vonarx-Coinsman V., Patrice T., Cloarec D., Xu X. N. and A. Combre (1992) Effects of high glucose concentration on survival and respiration of human endothelial cells. Biochimie 74, 975-979.