Optimization of chitosan succinate and chitosan phthalate microspheres for oral delivery of insulin using response surface methodology

Pharmaceutical Development and Technology

Volumn 14, Issue 1, 2009, Pages 99-108

  Ubaidulla, Udhumansha ^a   Khar, R K ^a   Ahmad, F J ^a   Tripathi, Purnima ^b  

^a HAMDARD UNIVERSITY   (India)

^b BUNDELKHAND UNIVERSITY   (India)

Author keywords

Chitosan phthalate; Chitosan succinate; Insulin; Oral insulin delivery; Response surface methodology

Indexed keywords

CHITOSAN DERIVATIVE; CHITOSAN PHTHALATE; CHITOSAN SUCCINATE; GLUCOSE; INSULIN; MICROSPHERE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; GLUCOSE BLOOD LEVEL; HYDROPHILICITY; IN VITRO STUDY; MALE; MATHEMATICAL MODEL; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; RESPONSE SURFACE METHOD; STREPTOZOCIN DIABETES; WISTAR RAT;

EID: 61649108123     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450802409461     Document Type: Article

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