-
1
-
-
0037012096
-
Selective photostimulation of genetically chARGed neurons
-
Zemelman B.V., Lee G.A., Ng M., and Miesenbock G. Selective photostimulation of genetically chARGed neurons. Neuron 33 (2002) 15-22
-
(2002)
Neuron
, vol.33
, pp. 15-22
-
-
Zemelman, B.V.1
Lee, G.A.2
Ng, M.3
Miesenbock, G.4
-
2
-
-
13944257374
-
Induction of photosensitivity by heterologous expression of melanopsin
-
Qiu X., Kumbalasiri T., Carlson S.M., Wong K.Y., Krishna V., Provencio I., and Berson D.M. Induction of photosensitivity by heterologous expression of melanopsin. Nature 433 (2005) 745-749
-
(2005)
Nature
, vol.433
, pp. 745-749
-
-
Qiu, X.1
Kumbalasiri, T.2
Carlson, S.M.3
Wong, K.Y.4
Krishna, V.5
Provencio, I.6
Berson, D.M.7
-
3
-
-
12844258225
-
Illumination of the melanopsin signaling pathway
-
Panda S., Nayak S.K., Campo B., Walker J.R., Hogenesch J.B., and Jegla T. Illumination of the melanopsin signaling pathway. Science 307 (2005) 600-604
-
(2005)
Science
, vol.307
, pp. 600-604
-
-
Panda, S.1
Nayak, S.K.2
Campo, B.3
Walker, J.R.4
Hogenesch, J.B.5
Jegla, T.6
-
4
-
-
13944275251
-
Addition of human melanopsin renders mammalian cells photoresponsive
-
Melyan Z., Tarttelin E.E., Bellingham J., Lucas R.J., and Hankins M.W. Addition of human melanopsin renders mammalian cells photoresponsive. Nature 433 (2005) 741-745
-
(2005)
Nature
, vol.433
, pp. 741-745
-
-
Melyan, Z.1
Tarttelin, E.E.2
Bellingham, J.3
Lucas, R.J.4
Hankins, M.W.5
-
6
-
-
0033280228
-
Visual transduction in Drosophila
-
Montell C. Visual transduction in Drosophila. Annu Rev Cell Dev Biol 15 (1999) 231-268
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 231-268
-
-
Montell, C.1
-
7
-
-
0033572358
-
The G protein subunit gene families
-
Downes G.B., and Gautam N. The G protein subunit gene families. Genomics 62 (1999) 544-552
-
(1999)
Genomics
, vol.62
, pp. 544-552
-
-
Downes, G.B.1
Gautam, N.2
-
8
-
-
0036662878
-
A genetic method for selective and quickly reversible silencing of Mammalian neurons
-
Lechner H.A., Lein E.S., and Callaway E.M. A genetic method for selective and quickly reversible silencing of Mammalian neurons. J Neurosci 22 (2002) 5287-5290
-
(2002)
J Neurosci
, vol.22
, pp. 5287-5290
-
-
Lechner, H.A.1
Lein, E.S.2
Callaway, E.M.3
-
9
-
-
33745880721
-
Selective and quickly reversible inactivation of Mammalian neurons in vivo using the Drosophila allatostatin receptor
-
i/o-coupled receptor, to silence neuronal function. Functionality in several tissues is demonstrated.
-
i/o-coupled receptor, to silence neuronal function. Functionality in several tissues is demonstrated.
-
(2006)
Neuron
, vol.51
, pp. 157-170
-
-
Tan, E.M.1
Yamaguchi, Y.2
Horwitz, G.D.3
Gosgnach, S.4
Lein, E.S.5
Goulding, M.6
Albright, T.D.7
Callaway, E.M.8
-
10
-
-
29144480494
-
Fast non-invasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin
-
This study uses the vertebrate rhodopsin and the green algae channelrhodopsin-2 (ChR2) to either hyperpolarize or depolarize the cell membrane of HEK293 cells, hippocampal neurons and chicken spinal cord. It is the first paper to demonstrate the use of antagonistically acting light switches in an intact tissue.
-
Li X., Gutierrez D., Hanson M.G., Han J., Mark M.D., Chiel H., Hegemann P., Landmesser L.T., and Herlitze S. Fast non-invasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. Proc Natl Acad Sci USA 102 (2005) 17816-17821. This study uses the vertebrate rhodopsin and the green algae channelrhodopsin-2 (ChR2) to either hyperpolarize or depolarize the cell membrane of HEK293 cells, hippocampal neurons and chicken spinal cord. It is the first paper to demonstrate the use of antagonistically acting light switches in an intact tissue.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17816-17821
-
-
Li, X.1
Gutierrez, D.2
Hanson, M.G.3
Han, J.4
Mark, M.D.5
Chiel, H.6
Hegemann, P.7
Landmesser, L.T.8
Herlitze, S.9
-
12
-
-
0037417982
-
Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons
-
Zemelman B.V., Nesnas N., Lee G.A., and Miesenbock G. Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons. Proc Natl Acad Sci USA 100 (2003) 1352-1357
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1352-1357
-
-
Zemelman, B.V.1
Nesnas, N.2
Lee, G.A.3
Miesenbock, G.4
-
13
-
-
0037130468
-
Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons
-
Tobin D., Madsen D., Kahn-Kirby A., Peckol E., Moulder G., Barstead R., Maricq A., and Bargmann C. Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons. Neuron 35 (2002) 307-318
-
(2002)
Neuron
, vol.35
, pp. 307-318
-
-
Tobin, D.1
Madsen, D.2
Kahn-Kirby, A.3
Peckol, E.4
Moulder, G.5
Barstead, R.6
Maricq, A.7
Bargmann, C.8
-
14
-
-
12344309164
-
Light-activated ion channels for remote control of neuronal firing
-
Banghart M., Borges K., Isacoff E., Trauner D., and Kramer R.H. Light-activated ion channels for remote control of neuronal firing. Nat Neurosci 7 (2004) 1381-1386
-
(2004)
Nat Neurosci
, vol.7
, pp. 1381-1386
-
-
Banghart, M.1
Borges, K.2
Isacoff, E.3
Trauner, D.4
Kramer, R.H.5
-
18
-
-
0035191854
-
The abundant retinal protein of the Chlamydomonas eye is not the photoreceptor for phototaxis and photophobic responses
-
Fuhrmann M., Stahlberg A., Govorunova E., Rank S., and Hegemann P. The abundant retinal protein of the Chlamydomonas eye is not the photoreceptor for phototaxis and photophobic responses. J Cell Sci 114 (2001) 3857-3863
-
(2001)
J Cell Sci
, vol.114
, pp. 3857-3863
-
-
Fuhrmann, M.1
Stahlberg, A.2
Govorunova, E.3
Rank, S.4
Hegemann, P.5
-
19
-
-
0030032226
-
The nature of rhodopsin-triggered photocurrents in Chlamydomonas. I. Kinetics and influence of divalent ions
-
Holland E.M., Braun F.J., Nonnengasser C., Harz H., and Hegemann P. The nature of rhodopsin-triggered photocurrents in Chlamydomonas. I. Kinetics and influence of divalent ions. Biophys J 70 (1996) 924-931
-
(1996)
Biophys J
, vol.70
, pp. 924-931
-
-
Holland, E.M.1
Braun, F.J.2
Nonnengasser, C.3
Harz, H.4
Hegemann, P.5
-
20
-
-
0037189362
-
Channelrhodopsin-1: a light-gated proton channel in green algae
-
Nagel G., Ollig D., Fuhrmann M., Kateriya S., Musti A.M., Bamberg E., and Hegemann P. Channelrhodopsin-1: a light-gated proton channel in green algae. Science 296 (2002) 2395-2398
-
(2002)
Science
, vol.296
, pp. 2395-2398
-
-
Nagel, G.1
Ollig, D.2
Fuhrmann, M.3
Kateriya, S.4
Musti, A.M.5
Bamberg, E.6
Hegemann, P.7
-
21
-
-
0345133280
-
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
-
Nagel G., Szellas T., Huhn W., Kateriya S., Adeishvili N., Berthold P., Ollig D., Hegemann P., and Bamberg E. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proc Natl Acad Sci USA 100 (2003) 13940-13945
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13940-13945
-
-
Nagel, G.1
Szellas, T.2
Huhn, W.3
Kateriya, S.4
Adeishvili, N.5
Berthold, P.6
Ollig, D.7
Hegemann, P.8
Bamberg, E.9
-
23
-
-
26444621497
-
Millisecond-timescale, genetically targeted optical control of neural activity
-
•] demonstrate that light activation of channelrhodopsin-2 (ChR2) can control action potential firing in hippocampal neurons.
-
•] demonstrate that light activation of channelrhodopsin-2 (ChR2) can control action potential firing in hippocampal neurons.
-
(2005)
Nat Neurosci
, vol.8
, pp. 1263-1268
-
-
Boyden, E.S.1
Zhang, F.2
Bamberg, E.3
Nagel, G.4
Deisseroth, K.5
-
24
-
-
0024430857
-
Giant synaptic potentials in immature rat CA3 hippocampal neurones
-
Ben-Ari Y., Cherubini E., Corradetti R., and Gaiarsa J.L. Giant synaptic potentials in immature rat CA3 hippocampal neurones. J Physiol 416 (1989) 303-325
-
(1989)
J Physiol
, vol.416
, pp. 303-325
-
-
Ben-Ari, Y.1
Cherubini, E.2
Corradetti, R.3
Gaiarsa, J.L.4
-
25
-
-
0025948834
-
GABA: an excitatory transmitter in early postnatal life
-
Cherubini E., Gaiarsa J.L., and Ben-Ari Y. GABA: an excitatory transmitter in early postnatal life. Trends Neurosci 14 (1991) 515-519
-
(1991)
Trends Neurosci
, vol.14
, pp. 515-519
-
-
Cherubini, E.1
Gaiarsa, J.L.2
Ben-Ari, Y.3
-
26
-
-
0035907025
-
GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition
-
Ganguly K., Schinder A.F., Wong S.T., and Poo M. GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. Cell 105 (2001) 521-532
-
(2001)
Cell
, vol.105
, pp. 521-532
-
-
Ganguly, K.1
Schinder, A.F.2
Wong, S.T.3
Poo, M.4
-
27
-
-
0026013580
-
Postnatal maturation of the GABAergic system in rat neocortex
-
Luhmann H.J., and Prince D.A. Postnatal maturation of the GABAergic system in rat neocortex. J Neurophysiol 65 (1991) 247-263
-
(1991)
J Neurophysiol
, vol.65
, pp. 247-263
-
-
Luhmann, H.J.1
Prince, D.A.2
-
28
-
-
0021262518
-
Development of hyperpolarizing inhibitory postsynaptic potentials and hyperpolarizing response to gamma-aminobutyric acid in rabbit hippocampus studied in vitro
-
Mueller A.L., Taube J.S., and Schwartzkroin P.A. Development of hyperpolarizing inhibitory postsynaptic potentials and hyperpolarizing response to gamma-aminobutyric acid in rabbit hippocampus studied in vitro. J Neurosci 4 (1984) 860-867
-
(1984)
J Neurosci
, vol.4
, pp. 860-867
-
-
Mueller, A.L.1
Taube, J.S.2
Schwartzkroin, P.A.3
-
29
-
-
0029794366
-
Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging
-
Owens D.F., Boyce L.H., Davis M.B., and Kriegstein A.R. Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging. J Neurosci 16 (1996) 6414-6423
-
(1996)
J Neurosci
, vol.16
, pp. 6414-6423
-
-
Owens, D.F.1
Boyce, L.H.2
Davis, M.B.3
Kriegstein, A.R.4
-
30
-
-
0036758648
-
Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels
-
Slimko E.M., McKinney S., Anderson D.J., Davidson N., and Lester H.A. Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels. J Neurosci 22 (2002) 7373-7379
-
(2002)
J Neurosci
, vol.22
, pp. 7373-7379
-
-
Slimko, E.M.1
McKinney, S.2
Anderson, D.J.3
Davidson, N.4
Lester, H.A.5
-
31
-
-
0028959025
-
Three-dimensional structure of halorhodopsin at 7 Å resolution
-
Havelka W.A., Henderson R., and Oesterhelt D. Three-dimensional structure of halorhodopsin at 7 Å resolution. J Mol Biol 247 (1995) 726-738
-
(1995)
J Mol Biol
, vol.247
, pp. 726-738
-
-
Havelka, W.A.1
Henderson, R.2
Oesterhelt, D.3
-
32
-
-
0028285064
-
Anion-protein interactions during halorhodopsin pumping: halide binding at the protonated Schiff base
-
Walter T.J., and Braiman M.S. Anion-protein interactions during halorhodopsin pumping: halide binding at the protonated Schiff base. Biochemistry 33 (1994) 1724-1733
-
(1994)
Biochemistry
, vol.33
, pp. 1724-1733
-
-
Walter, T.J.1
Braiman, M.S.2
-
33
-
-
17044431846
-
Remote control of behavior through genetically targeted photostimulation of neurons
-
This study shows that flight and locomotor behavior in flies can be controlled by light. It is the first demonstration that a light switch strategy can be applied in living animals to control small neuronal circuits underlying behavior.
-
Lima S.Q., and Miesenbock G. Remote control of behavior through genetically targeted photostimulation of neurons. Cell 121 (2005) 141-152. This study shows that flight and locomotor behavior in flies can be controlled by light. It is the first demonstration that a light switch strategy can be applied in living animals to control small neuronal circuits underlying behavior.
-
(2005)
Cell
, vol.121
, pp. 141-152
-
-
Lima, S.Q.1
Miesenbock, G.2
-
34
-
-
33645974269
-
Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration
-
In this study, ChR2 is expressed in retinal ganglion cells to convert this retinal cell type into a light-sensitive cell. It is also shown that light responses can be transmitted to higher brain areas of the visual cortex.
-
Bi A., Cui J., Ma Y.P., Olshevskaya E., Pu M., Dizhoor A.M., and Pan Z.H. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron 50 (2006) 23-33. In this study, ChR2 is expressed in retinal ganglion cells to convert this retinal cell type into a light-sensitive cell. It is also shown that light responses can be transmitted to higher brain areas of the visual cortex.
-
(2006)
Neuron
, vol.50
, pp. 23-33
-
-
Bi, A.1
Cui, J.2
Ma, Y.P.3
Olshevskaya, E.4
Pu, M.5
Dizhoor, A.M.6
Pan, Z.H.7
-
35
-
-
29044433616
-
Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses
-
The first demonstration that light activation of ChR2 induces depolarization-mediated contraction in muscle cells and can trigger withdrawal responses in C. elegans.
-
Nagel G., Brauner M., Liewald J.F., Adeishvili N., Bamberg E., and Gottschalk A. Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr Biol 15 (2005) 2279-2284. The first demonstration that light activation of ChR2 induces depolarization-mediated contraction in muscle cells and can trigger withdrawal responses in C. elegans.
-
(2005)
Curr Biol
, vol.15
, pp. 2279-2284
-
-
Nagel, G.1
Brauner, M.2
Liewald, J.F.3
Adeishvili, N.4
Bamberg, E.5
Gottschalk, A.6
-
36
-
-
0033028464
-
How vertebrate and invertebrate visual pigments differ in their mechanism of photoactivation
-
Nakagawa M., Iwasa T., Kikkawa S., Tsuda M., and Ebrey T.G. How vertebrate and invertebrate visual pigments differ in their mechanism of photoactivation. Proc Natl Acad Sci USA 96 (1999) 6189-6192
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6189-6192
-
-
Nakagawa, M.1
Iwasa, T.2
Kikkawa, S.3
Tsuda, M.4
Ebrey, T.G.5
-
37
-
-
0036802166
-
Evolution of the visual cycle: the role of retinoid-binding proteins
-
Gonzalez-Fernandez F. Evolution of the visual cycle: the role of retinoid-binding proteins. J Endocrinol 175 (2002) 75-88
-
(2002)
J Endocrinol
, vol.175
, pp. 75-88
-
-
Gonzalez-Fernandez, F.1
-
38
-
-
0036016545
-
HEK293S cells have functional retinoid processing machinery
-
Brueggemann L.I., and Sullivan J.M. HEK293S cells have functional retinoid processing machinery. J Gen Physiol 119 (2002) 593-612
-
(2002)
J Gen Physiol
, vol.119
, pp. 593-612
-
-
Brueggemann, L.I.1
Sullivan, J.M.2
-
39
-
-
0017152655
-
Light-dark conformational states in bacteriorhodopsin
-
Konishi T., and Packer L. Light-dark conformational states in bacteriorhodopsin. Biochem Biophys Res Commun 72 (1976) 1437-1442
-
(1976)
Biochem Biophys Res Commun
, vol.72
, pp. 1437-1442
-
-
Konishi, T.1
Packer, L.2
-
40
-
-
0017334993
-
Identification of retinal isomers isolated from bacteriorhodopsin
-
Pettei M.J., Yudd action potential, Nakanishi K., Henselman R., and Stoeckenius W. Identification of retinal isomers isolated from bacteriorhodopsin. Biochemistry 16 (1977) 1955-1959
-
(1977)
Biochemistry
, vol.16
, pp. 1955-1959
-
-
Pettei, M.J.1
Yudd action potential2
Nakanishi, K.3
Henselman, R.4
Stoeckenius, W.5
-
41
-
-
0342484454
-
Analogies between halorhodopsin and bacteriorhodopsin
-
Varo G. Analogies between halorhodopsin and bacteriorhodopsin. Biochim Biophys Acta 1460 (2000) 220-229
-
(2000)
Biochim Biophys Acta
, vol.1460
, pp. 220-229
-
-
Varo, G.1
-
42
-
-
0028808334
-
Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 2. Chloride release and uptake, protein conformation change, and thermodynamics
-
Varo G., Needleman R., and Lanyi J.K. Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 2. Chloride release and uptake, protein conformation change, and thermodynamics. Biochemistry 34 (1995) 14500-14507
-
(1995)
Biochemistry
, vol.34
, pp. 14500-14507
-
-
Varo, G.1
Needleman, R.2
Lanyi, J.K.3
-
43
-
-
28744446111
-
Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons
-
The authors present an alternative approach, using chemical-induced dimerization of the synaptic proteins, to block synaptic transmission reversibly once the chemical compound is applied.
-
Karpova A.Y., Tervo D.G., Gray N.W., and Svoboda K. Rapid and reversible chemical inactivation of synaptic transmission in genetically targeted neurons. Neuron 48 (2005) 727-735. The authors present an alternative approach, using chemical-induced dimerization of the synaptic proteins, to block synaptic transmission reversibly once the chemical compound is applied.
-
(2005)
Neuron
, vol.48
, pp. 727-735
-
-
Karpova, A.Y.1
Tervo, D.G.2
Gray, N.W.3
Svoboda, K.4
-
44
-
-
33749837676
-
Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae
-
Schroll C., Riemensperger T., Bucher D., Ehmer J., Voller T., Erbguth K., Gerber B., Hendel T., Nagel G., Buchner E., et al. Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae. Curr Biol 16 (2006) 1741-1747
-
(2006)
Curr Biol
, vol.16
, pp. 1741-1747
-
-
Schroll, C.1
Riemensperger, T.2
Bucher, D.3
Ehmer, J.4
Voller, T.5
Erbguth, K.6
Gerber, B.7
Hendel, T.8
Nagel, G.9
Buchner, E.10
-
45
-
-
33749848951
-
Next-generation optical technologies for illuminating genetically targeted brain circuits
-
Deisseroth K., Feng G., Majewska A.K., Miesenbock G., Ting A., and Schnitzer M.J. Next-generation optical technologies for illuminating genetically targeted brain circuits. J Neurosci 26 (2006) 10380-10386
-
(2006)
J Neurosci
, vol.26
, pp. 10380-10386
-
-
Deisseroth, K.1
Feng, G.2
Majewska, A.K.3
Miesenbock, G.4
Ting, A.5
Schnitzer, M.J.6
-
46
-
-
33749020262
-
Channelrhodopsin-2 and optical control of excitable cells
-
Zhang F., Wang L.P., Boyden E.S., and Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nat Methods 3 (2006) 785-792
-
(2006)
Nat Methods
, vol.3
, pp. 785-792
-
-
Zhang, F.1
Wang, L.P.2
Boyden, E.S.3
Deisseroth, K.4
-
47
-
-
33846877051
-
-
Schroder-Lang S, Schwarzel M, Seifert R, Strunker T, Kateriya S, Looser J, Watanabe M, Kaupp UB, Hegemann P, Nagel G: Fast manipulation of cellular cAMP level by light in vivo. Nat Methods 2006, in press.
-
-
-
|