메뉴 건너뛰기




Volumn 60, Issue 3, 2009, Pages 848-859

Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE; PRECIPITIN; PROLINE; RIBONUCLEOPROTEIN ANTIBODY;

EID: 61649090053     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24306     Document Type: Article
Times cited : (29)

References (51)
  • 2
    • 30844459010 scopus 로고    scopus 로고
    • Infections and SLE. Systemic lupus erythematosus: Genes versus environment in high risk populations
    • Zandman-Goddard G, Shoenfeld Y, Molokhia M, McKeigue P. Infections and SLE. Systemic lupus erythematosus: genes versus environment in high risk populations. Autoimmunity 2005;38: 473-85.
    • (2005) Autoimmunity , vol.38 , pp. 473-485
    • Zandman-Goddard, G.1    Shoenfeld, Y.2    Molokhia, M.3    McKeigue, P.4
  • 3
    • 22244459489 scopus 로고    scopus 로고
    • Longitudinal fluctuation of antibodies to extractable nuclear antigens in systemic lupus erythematosus
    • Faria AC, Barcellos KS, Andrade LE. Longitudinal fluctuation of antibodies to extractable nuclear antigens in systemic lupus erythematosus. J Rheumatol 2005;32:1267-72.
    • (2005) J Rheumatol , vol.32 , pp. 1267-1272
    • Faria, A.C.1    Barcellos, K.S.2    Andrade, L.E.3
  • 4
    • 0029932379 scopus 로고    scopus 로고
    • Prevalence and clinical significance of antibodies to ribonucleoproteins in systemic lupus erythematosus in Malaysia
    • Wang CL, Ooi L, Wang F. Prevalence and clinical significance of antibodies to ribonucleoproteins in systemic lupus erythematosus in Malaysia. Br J Rheumatol 1996;35:129-32.
    • (1996) Br J Rheumatol , vol.35 , pp. 129-132
    • Wang, C.L.1    Ooi, L.2    Wang, F.3
  • 6
    • 1542278085 scopus 로고    scopus 로고
    • An overview of the pathogenesis of systemic lupus erythematosus
    • Wallace DJ, Hahn BH, editors, 6th ed. Philadelphia: Lippincott Williams & Wilkins;
    • Hahn BH. An overview of the pathogenesis of systemic lupus erythematosus. In: Wallace DJ, Hahn BH, editors. Dubois' lupus erythematosus. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2002. p. 87.
    • (2002) Dubois' lupus erythematosus , pp. 87
    • Hahn, B.H.1
  • 8
    • 0028302604 scopus 로고
    • Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target
    • Fatenejad S, Brooks W, Schwartz A, Craft J. Pattern of anti-small nuclear ribonucleoprotein antibodies in MRL/Mp-lpr/lpr mice suggests that the intact U1 snRNP particle is their autoimmunogenic target. J Immunol 1994;152:5523-31.
    • (1994) J Immunol , vol.152 , pp. 5523-5531
    • Fatenejad, S.1    Brooks, W.2    Schwartz, A.3    Craft, J.4
  • 9
    • 32444435325 scopus 로고    scopus 로고
    • A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen
    • Greidinger EL, Zang Y, Jaimes K, Hogenmiller S, Nassiri M, Bejarano P, et al. A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Arthritis Rheum 2006;54:661-9.
    • (2006) Arthritis Rheum , vol.54 , pp. 661-669
    • Greidinger, E.L.1    Zang, Y.2    Jaimes, K.3    Hogenmiller, S.4    Nassiri, M.5    Bejarano, P.6
  • 10
    • 0035096401 scopus 로고    scopus 로고
    • The appearance of U1 RNP antibody specificities in sequential autoimmune human antisera follows a characteristic order that implicates the U1-70 kd and B′/B proteins as predominant U1 RNP immunogens
    • Greidinger EL, Hoffman RW. The appearance of U1 RNP antibody specificities in sequential autoimmune human antisera follows a characteristic order that implicates the U1-70 kd and B′/B proteins as predominant U1 RNP immunogens. Arthritis Rheum 2001;44:368-75.
    • (2001) Arthritis Rheum , vol.44 , pp. 368-375
    • Greidinger, E.L.1    Hoffman, R.W.2
  • 11
    • 0030005013 scopus 로고    scopus 로고
    • Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns
    • James JA, Harley JB. Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns. J Immunol 1996;156: 4018-26.
    • (1996) J Immunol , vol.156 , pp. 4018-4026
    • James, J.A.1    Harley, J.B.2
  • 12
    • 0034963121 scopus 로고    scopus 로고
    • Key sequences involved in the spreading of the systemic autoimmune response to spliceosomal proteins
    • Monneaux F, Muller S. Key sequences involved in the spreading of the systemic autoimmune response to spliceosomal proteins. Scand J Immunol 2001;54:45-54.
    • (2001) Scand J Immunol , vol.54 , pp. 45-54
    • Monneaux, F.1    Muller, S.2
  • 13
    • 2442524529 scopus 로고
    • Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes
    • Habets WJ, Sillekens PT, Hoet MH, McAllister G, Lerner MR, van Venrooij WJ. Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes. Proc Natl Acad Sci U S A 1989;86: 4674-8.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 4674-4678
    • Habets, W.J.1    Sillekens, P.T.2    Hoet, M.H.3    McAllister, G.4    Lerner, M.R.5    van Venrooij, W.J.6
  • 14
    • 0029018928 scopus 로고
    • Peptide autoantigenicity of the small nuclear ribonucleoprotein C
    • James JA, Harley JB. Peptide autoantigenicity of the small nuclear ribonucleoprotein C. Clin Exp Rheumatol 1995;13:299-305.
    • (1995) Clin Exp Rheumatol , vol.13 , pp. 299-305
    • James, J.A.1    Harley, J.B.2
  • 15
    • 0030606272 scopus 로고    scopus 로고
    • Comparison of two different methods using overlapping synthetic peptides for localizing linear B cell epitopes in the U1 snRNP-C autoantigen
    • Halimi H, Dumortier H, Briand JP, Muller S. Comparison of two different methods using overlapping synthetic peptides for localizing linear B cell epitopes in the U1 snRNP-C autoantigen. J Immunol Methods 1996;199:77-85.
    • (1996) J Immunol Methods , vol.199 , pp. 77-85
    • Halimi, H.1    Dumortier, H.2    Briand, J.P.3    Muller, S.4
  • 16
    • 0027456568 scopus 로고
    • B cell epitope on the U1 snRNP-C autoantigen contains a sequence similar to that of the herpes simplex virus protein
    • Misaki Y, Yamamoto K, Yanagi K, Miura H, Ichijo H, Kato T, et al. B cell epitope on the U1 snRNP-C autoantigen contains a sequence similar to that of the herpes simplex virus protein. Eur J Immunol 1993;23:1064-71.
    • (1993) Eur J Immunol , vol.23 , pp. 1064-1071
    • Misaki, Y.1    Yamamoto, K.2    Yanagi, K.3    Miura, H.4    Ichijo, H.5    Kato, T.6
  • 17
    • 0032433306 scopus 로고    scopus 로고
    • Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage
    • Hoet RM, Raats JM, de Wildt R, Dumortier H, Muller S, van den Hoogen F, et al. Human monoclonal autoantibody fragments from combinatorial antibody libraries directed to the U1snRNP associated U1C protein; epitope mapping, immunolocalization and V-gene usage. Mol Immunol 1998;35:1045-55.
    • (1998) Mol Immunol , vol.35 , pp. 1045-1055
    • Hoet, R.M.1    Raats, J.M.2    de Wildt, R.3    Dumortier, H.4    Muller, S.5    van den Hoogen, F.6
  • 18
    • 0028307063 scopus 로고
    • Basic amino acids predominate in the sequential autoantigenic determinants of the small nuclear 70K ribonucleoprotein
    • James JA, Scofield RH, Harley JB. Basic amino acids predominate in the sequential autoantigenic determinants of the small nuclear 70K ribonucleoprotein. Scand J Immunol 1994;39:557-66.
    • (1994) Scand J Immunol , vol.39 , pp. 557-566
    • James, J.A.1    Scofield, R.H.2    Harley, J.B.3
  • 19
    • 0023814672 scopus 로고
    • Epitope mapping with a recombinant human 68-kDa (U1) ribonucleoprotein antigen reveals heterogeneous autoantibody profiles in human autoimmune sera
    • Guldner HH, Netter HJ, Szostecki C, Lakomek HJ, Will H. Epitope mapping with a recombinant human 68-kDa (U1) ribonucleoprotein antigen reveals heterogeneous autoantibody profiles in human autoimmune sera. J Immunol 1988;141:469-75.
    • (1988) J Immunol , vol.141 , pp. 469-475
    • Guldner, H.H.1    Netter, H.J.2    Szostecki, C.3    Lakomek, H.J.4    Will, H.5
  • 20
    • 0024996223 scopus 로고
    • Mapping of multiple B cell epitopes on the 70-kilodalton autoantigen of the U1 ribonucleoprotein complex
    • Cram DS, Fisicaro N, Coppel RL, Whittingham S, Harrison LC. Mapping of multiple B cell epitopes on the 70-kilodalton autoantigen of the U1 ribonucleoprotein complex. J Immunol 1990;145: 630-5.
    • (1990) J Immunol , vol.145 , pp. 630-635
    • Cram, D.S.1    Fisicaro, N.2    Coppel, R.L.3    Whittingham, S.4    Harrison, L.C.5
  • 21
    • 0025340092 scopus 로고
    • Recombinant 70-kD protein used for determination of autoantigenic epitopes recognized by anti-RNP sera
    • Nyman U, Lundberg I, Hedfors E, Pettersson I. Recombinant 70-kD protein used for determination of autoantigenic epitopes recognized by anti-RNP sera. Clin Exp Immunol 1990;81:52-8.
    • (1990) Clin Exp Immunol , vol.81 , pp. 52-58
    • Nyman, U.1    Lundberg, I.2    Hedfors, E.3    Pettersson, I.4
  • 22
    • 0025826182 scopus 로고
    • Antigenic domains on the U1 small nuclear ribonucleoprotein-associated 70K polypeptide: A comparison of regions selectively recognized by human and mouse autoantibodies and by monoclonal antibodies
    • Takeda Y, Nyman U, Winkler A, Wise KS, Hoch SO, Pettersson I, et al. Antigenic domains on the U1 small nuclear ribonucleoprotein-associated 70K polypeptide: a comparison of regions selectively recognized by human and mouse autoantibodies and by monoclonal antibodies. Clin Immunol Immunopathol 1991;61: 55-68.
    • (1991) Clin Immunol Immunopathol , vol.61 , pp. 55-68
    • Takeda, Y.1    Nyman, U.2    Winkler, A.3    Wise, K.S.4    Hoch, S.O.5    Pettersson, I.6
  • 23
    • 0026556226 scopus 로고
    • Linear epitope mapping of an Sm B/B′ polypeptide
    • James JA, Harley JB. Linear epitope mapping of an Sm B/B′ polypeptide. J Immunol 1992;148:2074-9.
    • (1992) J Immunol , vol.148 , pp. 2074-2079
    • James, J.A.1    Harley, J.B.2
  • 24
    • 0032191315 scopus 로고    scopus 로고
    • A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif
    • Arbuckle MR, Schilling AR, Harley JB, James JA. A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif. J Autoimmun 1998;11:431-8.
    • (1998) J Autoimmun , vol.11 , pp. 431-438
    • Arbuckle, M.R.1    Schilling, A.R.2    Harley, J.B.3    James, J.A.4
  • 25
    • 0032695519 scopus 로고    scopus 로고
    • Shared early autoantibody recognition events in the development of anti-Sm B/B′ in human lupus
    • Arbuckle MR, Reichlin M, Harley JB, James JA. Shared early autoantibody recognition events in the development of anti-Sm B/B′ in human lupus. Scand J Immunol 1999;50:447-55.
    • (1999) Scand J Immunol , vol.50 , pp. 447-455
    • Arbuckle, M.R.1    Reichlin, M.2    Harley, J.B.3    James, J.A.4
  • 26
    • 0028912625 scopus 로고
    • Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B′-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity
    • James JA, Gross T, Scofield RH, Harley JB. Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B′-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity. J Exp Med 1995;181:453-61.
    • (1995) J Exp Med , vol.181 , pp. 453-461
    • James, J.A.1    Gross, T.2    Scofield, R.H.3    Harley, J.B.4
  • 29
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]
    • for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology
    • Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 31
    • 0018251177 scopus 로고
    • Patterns of clinical disease associated with antibodies to nuclear ribonucleoprotein
    • Maddison PJ, Mogavero H, Reichlin M. Patterns of clinical disease associated with antibodies to nuclear ribonucleoprotein. J Rheumatol 1978;5:407-11.
    • (1978) J Rheumatol , vol.5 , pp. 407-411
    • Maddison, P.J.1    Mogavero, H.2    Reichlin, M.3
  • 32
    • 0037083362 scopus 로고    scopus 로고
    • Anti-Sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens
    • McClain MT, Ramsland PA, Kaufman KM, James JA. Anti-Sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens. J Immunol 2002; 168:2054-62.
    • (2002) J Immunol , vol.168 , pp. 2054-2062
    • McClain, M.T.1    Ramsland, P.A.2    Kaufman, K.M.3    James, J.A.4
  • 33
    • 0030024350 scopus 로고    scopus 로고
    • Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro
    • Lutz CS, Murthy KG, Schek N, O'Connor JP, Manley JL, Alwine JC. Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev 1996;10:325-37.
    • (1996) Genes Dev , vol.10 , pp. 325-337
    • Lutz, C.S.1    Murthy, K.G.2    Schek, N.3    O'Connor, J.P.4    Manley, J.L.5    Alwine, J.C.6
  • 36
    • 0025778716 scopus 로고
    • Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein
    • Nelissen RL, Sillekens PT, Beijer RP, Geurts van Kessel AH, van Venrooij WJ. Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein. Gene 1991;102:189-96.
    • (1991) Gene , vol.102 , pp. 189-196
    • Nelissen, R.L.1    Sillekens, P.T.2    Beijer, R.P.3    Geurts van Kessel, A.H.4    van Venrooij, W.J.5
  • 37
    • 0032695519 scopus 로고    scopus 로고
    • The development of lupus humoral autoimmunity for anti-Sm autoantibodies is consistent with predictable sequential B cell epitope spreading
    • Arbuckle MR, Reichlin M, Harley JB, James JA. The development of lupus humoral autoimmunity for anti-Sm autoantibodies is consistent with predictable sequential B cell epitope spreading. Scand J Immunol 1999;50:447-55.
    • (1999) Scand J Immunol , vol.50 , pp. 447-455
    • Arbuckle, M.R.1    Reichlin, M.2    Harley, J.B.3    James, J.A.4
  • 38
    • 33846908279 scopus 로고    scopus 로고
    • A SmD peptide induces better antibody responses to other proteins within the small nuclear ribonucleoprotein complex than to SmD protein via intermolecular epitope spreading
    • Deshmukh US, Bagavant H, Sim D, Pidiyar V, Fu SM. A SmD peptide induces better antibody responses to other proteins within the small nuclear ribonucleoprotein complex than to SmD protein via intermolecular epitope spreading. J Immunol 2007;178: 2565-71.
    • (2007) J Immunol , vol.178 , pp. 2565-2571
    • Deshmukh, U.S.1    Bagavant, H.2    Sim, D.3    Pidiyar, V.4    Fu, S.M.5
  • 39
    • 0037094031 scopus 로고    scopus 로고
    • Immune responses to small nuclear ribonucleoproteins: Antigen-dependent distinct B cell epitope spreading patterns in mice immunized with recombinant polypeptides of small nuclear ribonucleoproteins
    • Deshmukh US, Kannapell CC, Fu SM. Immune responses to small nuclear ribonucleoproteins: antigen-dependent distinct B cell epitope spreading patterns in mice immunized with recombinant polypeptides of small nuclear ribonucleoproteins. J Immunol 2002;168:5326-32.
    • (2002) J Immunol , vol.168 , pp. 5326-5332
    • Deshmukh, U.S.1    Kannapell, C.C.2    Fu, S.M.3
  • 40
    • 33745115404 scopus 로고    scopus 로고
    • Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus
    • Poole BD, Scofield RH, Harley JB, James JA. Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus. Autoimmunity 2006;39:63-70.
    • (2006) Autoimmunity , vol.39 , pp. 63-70
    • Poole, B.D.1    Scofield, R.H.2    Harley, J.B.3    James, J.A.4
  • 41
    • 0025676094 scopus 로고
    • A repeated proline-rich sequence in Sm B/B′ and N is a dominant epitope recognized by human and murine autoantibodies
    • Williams DG, Sharpe NG, Wallace G, Latchman DS. A repeated proline-rich sequence in Sm B/B′ and N is a dominant epitope recognized by human and murine autoantibodies. J Autoimmun 1990;3:715-25.
    • (1990) J Autoimmun , vol.3 , pp. 715-725
    • Williams, D.G.1    Sharpe, N.G.2    Wallace, G.3    Latchman, D.S.4
  • 42
    • 0031882733 scopus 로고    scopus 로고
    • A model of peptide-induced lupus autoimmune B cell epitope spreading is strain specific and is not H-2 restricted in mice
    • James JA, Harley JB. A model of peptide-induced lupus autoimmune B cell epitope spreading is strain specific and is not H-2 restricted in mice. J Immunol 1998;160:502-8.
    • (1998) J Immunol , vol.160 , pp. 502-508
    • James, J.A.1    Harley, J.B.2
  • 44
    • 25444506843 scopus 로고    scopus 로고
    • Clinical relevance of measurement of antibodies to individual snU1-RNP proteins
    • Luyckx A, Westhovens R, Oris E, Papisch W, Bossuyt X. Clinical relevance of measurement of antibodies to individual snU1-RNP proteins. Clin Chem 2005;51:1888-90.
    • (2005) Clin Chem , vol.51 , pp. 1888-1890
    • Luyckx, A.1    Westhovens, R.2    Oris, E.3    Papisch, W.4    Bossuyt, X.5
  • 45
    • 0023663088 scopus 로고
    • A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen
    • Query CC, Keene JD. A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. Cell 1987;51:211-20.
    • (1987) Cell , vol.51 , pp. 211-220
    • Query, C.C.1    Keene, J.D.2
  • 46
    • 0033511928 scopus 로고    scopus 로고
    • Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers [letter]
    • Harley JB, James JA. Epstein-Barr virus infection may be an environmental risk factor for systemic lupus erythematosus in children and teenagers [letter]. Arthritis Rheum 1999;42:1782-3.
    • (1999) Arthritis Rheum , vol.42 , pp. 1782-1783
    • Harley, J.B.1    James, J.A.2
  • 47
    • 0035036288 scopus 로고    scopus 로고
    • Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure
    • James JA, Neas BR, Moser KL, Hall T, Bruner GR, Sestak AL, et al. Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthritis Rheum 2001;44: 1122-6.
    • (2001) Arthritis Rheum , vol.44 , pp. 1122-1126
    • James, J.A.1    Neas, B.R.2    Moser, K.L.3    Hall, T.4    Bruner, G.R.5    Sestak, A.L.6
  • 48
    • 0030840877 scopus 로고    scopus 로고
    • Lupus humoral autoimmunity after short peptide immunization
    • James JA, Scofield RH, Harley JB. Lupus humoral autoimmunity after short peptide immunization. Ann N Y Acad Sci 1997;815: 124-7.
    • (1997) Ann N Y Acad Sci , vol.815 , pp. 124-127
    • James, J.A.1    Scofield, R.H.2    Harley, J.B.3
  • 50
    • 8444252900 scopus 로고    scopus 로고
    • Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies
    • Sundar K, Jacques S, Gottlieb P, Villars R, Benito ME, Taylor DK, et al. Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies. J Autoimmun 2004;23:127-40.
    • (2004) J Autoimmun , vol.23 , pp. 127-140
    • Sundar, K.1    Jacques, S.2    Gottlieb, P.3    Villars, R.4    Benito, M.E.5    Taylor, D.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.