Transduced viral IL-10 is exocytosed from lacrimal acinar secretory vesicles in a myosin-dependent manner in response to carbachol

Experimental Eye Research

Volumn 88, Issue 3, 2009, Pages 467-478

  Xie, Jiansong ^a   Marchelletta, Ronald R ^a   Thomas, Padmaja B ^a,b   Jacobs, Damon T ^c   Yarber, Francie A ^a   Cheney, Richard E ^c   Hamm Alvarez, Sarah F ^a,b   Trousdale, Melvin D ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

cytokines; gene therapy; interleukin 10; lacrimal gland; Myo5c; myosin; ocular surface

Indexed keywords

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; ACTIN; BETA N ACETYLHEXOSAMINIDASE; CARBACHOL; INTERLEUKIN 10; LATRUNCULIN B; MYOSIN;

ACINAR CELL; ACTIN FILAMENT; ADENOVIRUS 5; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOCYTOSIS; EXPERIMENTAL RABBIT; FEMALE; FLUORESCENCE MICROSCOPY; IMMUNOREACTIVITY; LACRIMAL GLAND; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SECRETORY VESICLE; TRANSGENE;

ADENOVIRIDAE; ANIMALS; CARBACHOL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EXOCYTOSIS; FEMALE; GENETIC VECTORS; INTERLEUKIN-10; LACRIMAL APPARATUS; MICROFILAMENTS; MICROSCOPY, CONFOCAL; MYOSINS; RABBITS; SECRETORY VESICLES; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC;

EID: 61549137496     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.10.023     Document Type: Article

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