메뉴 건너뛰기




Volumn 18, Issue 1, 1998, Pages 15-26

A gene therapy approach to treatment of autoimmune disease

Author keywords

Autoimmunity; Gene therapy; Immune deviation; Th1 CD4+ T cell

Indexed keywords

ANIMAL MODEL; AUTOIMMUNE DISEASE; GENE THERAPY; HELPER CELL; HUMAN; IMMUNOLOGICAL TOLERANCE; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0031711070     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02786510     Document Type: Review
Times cited : (5)

References (49)
  • 1
    • 0028890866 scopus 로고
    • Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
    • Liblau RS, Singer SM, McDevitt HO. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases [see comments]. Immunol Today 1995;16, 1:34-38.
    • (1995) Immunol Today , vol.16 , Issue.1 , pp. 34-38
    • Liblau, R.S.1    Singer, S.M.2    McDevitt, H.O.3
  • 2
    • 0027529932 scopus 로고
    • Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma
    • Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway Jr., CA. Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J Exp Med 1993;177, 1:57-68.
    • (1993) J Exp Med , vol.177 , Issue.1 , pp. 57-68
    • Baron, J.L.1    Madri, J.A.2    Ruddle, N.H.3    Hashim, G.4    Janeway Jr., C.A.5
  • 3
    • 0027141832 scopus 로고
    • Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: Relative roles of interleukin (IL)-4 and IL-10
    • van der Veen RC, Stohlman SA. Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: relative roles of interleukin (IL)-4 and IL-10. J Neuroimmunol 1993;48, 2:213-220.
    • (1993) J Neuroimmunol , vol.48 , Issue.2 , pp. 213-220
    • Van Der Veen, R.C.1    Stohlman, S.A.2
  • 4
    • 0023905174 scopus 로고
    • Isolation of T cell line capable of protecting mice against collagen-induced arthritis
    • Kakimoto K, Katsuki M, Hirofuji T, Iwata H, Koga T. Isolation of T cell line capable of protecting mice against collagen-induced arthritis. J Immunol 1988;140, 1:78-83.
    • (1988) J Immunol , vol.140 , Issue.1 , pp. 78-83
    • Kakimoto, K.1    Katsuki, M.2    Hirofuji, T.3    Iwata, H.4    Koga, T.5
  • 5
    • 0028518985 scopus 로고
    • Generation and in vivo persistence of polarized Th1 and Th2 memory cells
    • Swain SL. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity 1994;1,7:543-552.
    • (1994) Immunity , vol.1 , Issue.7 , pp. 543-552
    • Swain, S.L.1
  • 6
    • 0028979063 scopus 로고
    • The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro
    • Bradley LM, Yoshimoto K, Swain SL. The cytokines IL-4, IFN-gamma, and IL-12 regulate the development of subsets of memory effector helper T cells in vitro. J Immunol 1995;155, 4:1713-1724.
    • (1995) J Immunol , vol.155 , Issue.4 , pp. 1713-1724
    • Bradley, L.M.1    Yoshimoto, K.2    Swain, S.L.3
  • 7
    • 0027443372 scopus 로고
    • Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
    • Secrist H, Chelen CJ, Wen Y, Marshall JD, Umetsu DT. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med 1993;178,6:2123-2130.
    • (1993) J Exp Med , vol.178 , Issue.6 , pp. 2123-2130
    • Secrist, H.1    Chelen, C.J.2    Wen, Y.3    Marshall, J.D.4    Umetsu, D.T.5
  • 10
    • 0029126723 scopus 로고
    • Bee venom immunotherapy induces a shift in cytokine responses from a TH-2 to a TH-1 dominant pattern: Comparison of rush and conventional immunotherapy
    • McHugh SM, Deighton J, Stewart AG, Lachmann PJ, Ewan PW. Bee venom immunotherapy induces a shift in cytokine responses from a TH-2 to a TH-1 dominant pattern: comparison of rush and conventional immunotherapy. Clin Exp Allergy 1995;25,9:828-838.
    • (1995) Clin Exp Allergy , vol.25 , Issue.9 , pp. 828-838
    • McHugh, S.M.1    Deighton, J.2    Stewart, A.G.3    Lachmann, P.J.4    Ewan, P.W.5
  • 11
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • Varney VA, Hamid QA, Gaga M, Ying S, Jacobson M, Frew AJ, Kay AB, Durham SR. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993;92, 2:644-651.
    • (1993) J Clin Invest , vol.92 , Issue.2 , pp. 644-651
    • Varney, V.A.1    Hamid, Q.A.2    Gaga, M.3    Ying, S.4    Jacobson, M.5    Frew, A.J.6    Kay, A.B.7    Durham, S.R.8
  • 12
    • 0028201726 scopus 로고
    • Acquisition of lymphokineproducing phenotype by CD4+ T cells
    • Seder RA, Paul WE. Acquisition of lymphokineproducing phenotype by CD4+ T cells. Annu Rev Immunol 1994;12:635-673.
    • (1994) Annu Rev Immunol , vol.12 , pp. 635-673
    • Seder, R.A.1    Paul, W.E.2
  • 13
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and pro-staglandin E expression in the brain
    • Khoury SJ, Hancock WW, Weiner HL. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and pro-staglandin E expression in the brain. J Exp Med 1992;176,5:1355-1364.
    • (1992) J Exp Med , vol.176 , Issue.5 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 14
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy MK, Torrance DS, Picha KS, Mohler KM. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 1992; 149,7:2496-2505.
    • (1992) J Immunol , vol.149 , Issue.7 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 15
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • Weiner HL. Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol Today 1997;18,7:335-343.
    • (1997) Immunol Today , vol.18 , Issue.7 , pp. 335-343
    • Weiner, H.L.1
  • 16
    • 0028956146 scopus 로고
    • Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand
    • Windhagen A, Scholz C, Hollsberg P, Fukaura H, Sette A, Hafler DA. Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity 1995;2,4:373-380.
    • (1995) Immunity , vol.2 , Issue.4 , pp. 373-380
    • Windhagen, A.1    Scholz, C.2    Hollsberg, P.3    Fukaura, H.4    Sette, A.5    Hafler, D.A.6
  • 17
    • 0028919877 scopus 로고
    • Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo
    • Pfeiffer C, Stein J, Southwood S, Ketelaar H, Sette A, Bottomly K. Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J Exp Med 1995; 181,4:1569-1574.
    • (1995) J Exp Med , vol.181 , Issue.4 , pp. 1569-1574
    • Pfeiffer, C.1    Stein, J.2    Southwood, S.3    Ketelaar, H.4    Sette, A.5    Bottomly, K.6
  • 18
    • 0030069797 scopus 로고    scopus 로고
    • Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein
    • Brocke S, Gijbels K, Allegretta M, Ferber I, Piercy C, Blankenstein T, et al. Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein. Nature 1996;379,6563: 343-346.
    • (1996) Nature , vol.379 , Issue.6563 , pp. 343-346
    • Brocke, S.1    Gijbels, K.2    Allegretta, M.3    Ferber, I.4    Piercy, C.5    Blankenstein, T.6
  • 20
    • 0030843493 scopus 로고    scopus 로고
    • HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia
    • Bonini C, Ferrari G, Verzeletti S, Servida P, Zappone E, Ruggieri L, et al. HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia [see comments]. Science 1997; 276, 5319:1719-1724.
    • (1997) Science , vol.276 , Issue.5319 , pp. 1719-1724
    • Bonini, C.1    Ferrari, G.2    Verzeletti, S.3    Servida, P.4    Zappone, E.5    Ruggieri, L.6
  • 21
    • 0030473830 scopus 로고    scopus 로고
    • Gene therapy for hematopoietic and immune disorders
    • Kohn DB. Gene therapy for hematopoietic and immune disorders. Bone Marrow Transplant 1996;18 Suppl 3:S55-S58.
    • (1996) Bone Marrow Transplant , vol.18 , Issue.3 SUPPL.
    • Kohn, D.B.1
  • 22
    • 19144364120 scopus 로고    scopus 로고
    • Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis
    • Evans CH, Robbins PD, Ghivizzani SC, Hemdon JH., Kang R, Bahnson AB, et al. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. Hum Gene Ther 1996;7, 10:1261-1280.
    • (1996) Hum Gene Ther , vol.7 , Issue.10 , pp. 1261-1280
    • Evans, C.H.1    Robbins, P.D.2    Ghivizzani, S.C.3    Hemdon, J.H.4    Kang, R.5    Bahnson, A.B.6
  • 23
    • 0027169443 scopus 로고
    • Report to the NIH Recombinant DNA Advisory Committee on murine replication-competent retrovirus (RCR) assays
    • February 17, 1993
    • Anderson WF, McGarrity GJ, Moen RC. Report to the NIH Recombinant DNA Advisory Committee on murine replication-competent retrovirus (RCR) assays (February 17, 1993). Hum Gene Ther 1993;4,3:311-321.
    • (1993) Hum Gene Ther , vol.4 , Issue.3 , pp. 311-321
    • Anderson, W.F.1    McGarrity, G.J.2    Moen, R.C.3
  • 24
    • 13344249764 scopus 로고    scopus 로고
    • Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival
    • Qin L, Chavin KD, Ding Y, Tahara H, Favaro JP, Woodward JE, et al. Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival. J Immunol 1996;156,6:2316-2323.
    • (1996) J Immunol , vol.156 , Issue.6 , pp. 2316-2323
    • Qin, L.1    Chavin, K.D.2    Ding, Y.3    Tahara, H.4    Favaro, J.P.5    Woodward, J.E.6
  • 25
    • 0028567517 scopus 로고
    • Tissue-specific targeting of retro-viral vectors through ligand-receptor interactions
    • Kasahara N, Dozy AM, Kan YW. Tissue-specific targeting of retro-viral vectors through ligand-receptor interactions [see comments]. Science 1994;266,5189: 1373-1376.
    • (1994) Science , vol.266 , Issue.5189 , pp. 1373-1376
    • Kasahara, N.1    Dozy, A.M.2    Kan, Y.W.3
  • 26
    • 0029165356 scopus 로고
    • Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis
    • Crystal RG, Mastrangeli A, Sanders A, Cooke J, King T, Gilbert F, et al. Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis. Hum Gene Ther 1995;6,5:667-703.
    • (1995) Hum Gene Ther , vol.6 , Issue.5 , pp. 667-703
    • Crystal, R.G.1    Mastrangeli, A.2    Sanders, A.3    Cooke, J.4    King, T.5    Gilbert, F.6
  • 27
    • 16944367323 scopus 로고    scopus 로고
    • Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial
    • Bellon G, Michel-Calemard L, Thouvenot D, Jagneaux V, Poitevin F, Malcus,C, et al. Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: a phase I clinical trial. Hum Gene Ther 1997;8,1:15-25.
    • (1997) Hum Gene Ther , vol.8 , Issue.1 , pp. 15-25
    • Bellon, G.1    Michel-Calemard, L.2    Thouvenot, D.3    Jagneaux, V.4    Poitevin, F.5    Malcus, C.6
  • 29
    • 0030970938 scopus 로고    scopus 로고
    • Recombinant adeno-associated viral vectors mediate long-term transgene expression in muscle
    • Clark KR, Sferra TJ, Johnson PR. Recombinant adeno-associated viral vectors mediate long-term transgene expression in muscle. Hum Gene Ther 1997;8,6: 659-669.
    • (1997) Hum Gene Ther , vol.8 , Issue.6 , pp. 659-669
    • Clark, K.R.1    Sferra, T.J.2    Johnson, P.R.3
  • 30
    • 0030953655 scopus 로고    scopus 로고
    • Adeno-associated virus type 2-mediated transfer of ecotropic retrovirus receptor cDNA allows ecotropic retroviral transduction of established and primary human cells
    • Qing K, Bachelot T, Mukherjee P, Wang XS, Peng L, Yoder MC, Leboulch P, Srivastava A. Adeno-associated virus type 2-mediated transfer of ecotropic retrovirus receptor cDNA allows ecotropic retroviral transduction of established and primary human cells. J Virol 1997;71,7:5663-5667.
    • (1997) J Virol , vol.71 , Issue.7 , pp. 5663-5667
    • Qing, K.1    Bachelot, T.2    Mukherjee, P.3    Wang, X.S.4    Peng, L.5    Yoder, M.C.6    Leboulch, P.7    Srivastava, A.8
  • 32
    • 10544254263 scopus 로고    scopus 로고
    • Systemic high-dose recombinant-alpha-2a-interferon therapy modulates lymphokine production in multiple sclerosis
    • Bongioanni MR, Durelli L, Ferrero B, Imperiale D, Oggero A, Verdun E, et al. Systemic high-dose recombinant-alpha-2a-interferon therapy modulates lymphokine production in multiple sclerosis. J Neurol Sci 1996; 143,1-2:91-99.
    • (1996) J Neurol Sci , vol.143 , Issue.1-2 , pp. 91-99
    • Bongioanni, M.R.1    Durelli, L.2    Ferrero, B.3    Imperiale, D.4    Oggero, A.5    Verdun, E.6
  • 33
    • 0027438710 scopus 로고
    • Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha
    • Elliott MJ, Maini RN, Feldmann M, Long-Fox A, Charles P, Katsikis P, et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha. Arthritis Rheum 1993;36, 12:1681-1690.
    • (1993) Arthritis Rheum , vol.36 , Issue.12 , pp. 1681-1690
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Long-Fox, A.4    Charles, P.5    Katsikis, P.6
  • 34
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, Kalden JR, Antoni C, Smolen JS, et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344,8930:1105-1110.
    • (1994) Lancet , vol.344 , Issue.8930 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Kalden, J.R.4    Antoni, C.5    Smolen, J.S.6
  • 35
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland LW, Baumgartner SW, Schiff MH, Tindall EA, Fleischmann RM, Weaver AL, et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein [see comments]. N Engl J Med 1997;337,3:141-147.
    • (1997) N Engl J Med , vol.337 , Issue.3 , pp. 141-147
    • Moreland, L.W.1    Baumgartner, S.W.2    Schiff, M.H.3    Tindall, E.A.4    Fleischmann, R.M.5    Weaver, A.L.6
  • 36
    • 0026758968 scopus 로고
    • Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody
    • Linington C, Engelhardt B, Kapocs G, Lassman H. Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody. J Neuroimmunol 1992;40, 2-3:219-224.
    • (1992) J Neuroimmunol , vol.40 , Issue.2-3 , pp. 219-224
    • Linington, C.1    Engelhardt, B.2    Kapocs, G.3    Lassman, H.4
  • 37
    • 0026635926 scopus 로고
    • The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions
    • Sobel RA, Kuchroo VK. The immunopathology of acute experimental allergic encephalomyelitis induced with myelin proteolipid protein. T cell receptors in inflammatory lesions. J Immunol 1992; 149, 4:1444-1451.
    • (1992) J Immunol , vol.149 , Issue.4 , pp. 1444-1451
    • Sobel, R.A.1    Kuchroo, V.K.2
  • 38
    • 0026721247 scopus 로고
    • Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein
    • McRae BL, Kennedy MK, Tan LJ, Dal Canto MC, Picha KS, Miller SD. Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein. J Neuroimmunol 1992;38,3:229-240.
    • (1992) J Neuroimmunol , vol.38 , Issue.3 , pp. 229-240
    • McRae, B.L.1    Kennedy, M.K.2    Tan, L.J.3    Dal Canto, M.C.4    Picha, K.S.5    Miller, S.D.6
  • 39
    • 0030918701 scopus 로고    scopus 로고
    • Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis
    • Shaw MK, Lorens JB, Dhawan A, DalCanto R, Tse HY, Tran AB, et al. Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. J Exp Med 1997;185, 9:1711-1714.
    • (1997) J Exp Med , vol.185 , Issue.9 , pp. 1711-1714
    • Shaw, M.K.1    Lorens, J.B.2    Dhawan, A.3    DalCanto, R.4    Tse, H.Y.5    Tran, A.B.6
  • 40
    • 0030738659 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells
    • Mathisen PM, Yu M, Johnson JM, Drazba JA, Tuohy VK. Treatment of experimental autoimmune encephalomyelitis with genetically modified memory T cells. J Exp Med 1997;186,1:159-164.
    • (1997) J Exp Med , vol.186 , Issue.1 , pp. 159-164
    • Mathisen, P.M.1    Yu, M.2    Johnson, J.M.3    Drazba, J.A.4    Tuohy, V.K.5
  • 41
    • 0017657009 scopus 로고
    • Autoimmunity to type II collagen an experimental model of arthritis
    • Trentham DE, Townes AS, Kang AH. Autoimmunity to type II collagen an experimental model of arthritis. J Exp Med 1977;146, 3:857-868.
    • (1977) J Exp Med , vol.146 , Issue.3 , pp. 857-868
    • Trentham, D.E.1    Townes, A.S.2    Kang, A.H.3
  • 42
    • 0028226982 scopus 로고
    • Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis
    • Williams RO, Mason LJ, Feldmann M, Maini RN. Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis. Proc Natl Acad Sci USA 1994;91,7:2762-2766.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.7 , pp. 2762-2766
    • Williams, R.O.1    Mason, L.J.2    Feldmann, M.3    Maini, R.N.4
  • 43
    • 0022385994 scopus 로고
    • T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T-cell lines and clones
    • Holmdahl R, Klareskog L, Rubin K, Larsson E, Wigzell H. T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T-cell lines and clones. Scand J Immunol 1985;22,3:295-306.
    • (1985) Scand J Immunol , vol.22 , Issue.3 , pp. 295-306
    • Holmdahl, R.1    Klareskog, L.2    Rubin, K.3    Larsson, E.4    Wigzell, H.5
  • 44
    • 0030267786 scopus 로고    scopus 로고
    • Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice
    • Mori L, Iselin S, De Libero G, Lesslauer W. Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice. J Immunol 1996;157, 7:3178-182.
    • (1996) J Immunol , vol.157 , Issue.7 , pp. 3178-3182
    • Mori, L.1    Iselin, S.2    De Libero, G.3    Lesslauer, W.4
  • 45
    • 0029797868 scopus 로고    scopus 로고
    • Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13
    • Bessis N, Boissier MC, Ferrara P, Blankenstein T, Fradelizi D, Fournier C. Attenuation of collagen-induced arthritis in mice by treatment with vector cells engineered to secrete interleukin-13. Eur J Immunol 1996;26,10:2399-2403.
    • (1996) Eur J Immunol , vol.26 , Issue.10 , pp. 2399-2403
    • Bessis, N.1    Boissier, M.C.2    Ferrara, P.3    Blankenstein, T.4    Fradelizi, D.5    Fournier, C.6
  • 46
    • 0029559755 scopus 로고
    • Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor
    • Chernajovsky Y, Adams G, Podhajcer OL, Mueller GM, Robbins PD, Feldmann M. Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor. Gene Ther 1995;2, 10:731-735.
    • (1995) Gene Ther , vol.2 , Issue.10 , pp. 731-735
    • Chernajovsky, Y.1    Adams, G.2    Podhajcer, O.L.3    Mueller, G.M.4    Robbins, P.D.5    Feldmann, M.6
  • 47
    • 0030813880 scopus 로고    scopus 로고
    • Pathogenic lymphoid cells engineered to express TGF beta 1 ameliorate disease in a collagen-induced arthritis model
    • Chernajovsky Y, Adams G, Triantaphyllopoulos K, Ledda MF, Podhajcer OL. Pathogenic lymphoid cells engineered to express TGF beta 1 ameliorate disease in a collagen-induced arthritis model. Gene Ther 1997;4,6:553-559.
    • (1997) Gene Ther , vol.4 , Issue.6 , pp. 553-559
    • Chernajovsky, Y.1    Adams, G.2    Triantaphyllopoulos, K.3    Ledda, M.F.4    Podhajcer, O.L.5
  • 48
    • 0029838995 scopus 로고    scopus 로고
    • Pancreatic expression of interleukin-4 abrogates insulitis and a diabetes in nonobese diabetic (NOD) mice
    • Mueller R, Krahl T, Sarvetnick N. Pancreatic expression of interleukin-4 abrogates insulitis and a diabetes in nonobese diabetic (NOD) mice. J Exp Med 1996; 184,3:1093-1099.
    • (1996) J Exp Med , vol.184 , Issue.3 , pp. 1093-1099
    • Mueller, R.1    Krahl, T.2    Sarvetnick, N.3
  • 49
    • 10244224047 scopus 로고    scopus 로고
    • Prevention of adoptively transferred diabetes in nonobese diabet with IL-10-transduced islet-specific Th1 lymphocytes. A gene the model for autoimmune diabetes
    • Moritani M, Yoshimoto K, Li S, Kondo M, Iwahana H, Yamaoka T, et al. Prevention of adoptively transferred diabetes in nonobese diabet with IL-10-transduced islet-specific Th1 lymphocytes. A gene the model for autoimmune diabetes. J Clin Invest 1996;98, 8:1851-1859.
    • (1996) J Clin Invest , vol.98 , Issue.8 , pp. 1851-1859
    • Moritani, M.1    Yoshimoto, K.2    Li, S.3    Kondo, M.4    Iwahana, H.5    Yamaoka, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.