The presence and activity of SP-D in porcine coronary endothelial cells depend on Akt/PI3K, Erk and nitric oxide and decrease after multiple passaging

Molecular Immunology

Volumn 46, Issue 6, 2009, Pages 1050-1057

  Lee, Mary Y K ^a   Sørensen, Grith L ^b   Holmskov, Uffe ^b   Vanhoutte, Paul M ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Endothelial cells; Nitric oxide; SP D; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INSULIN; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B BETA; SURFACTANT PROTEIN D; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORONARY ARTERY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXPERIMENTAL PIG; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION;

ANIMALS; CELLS, CULTURED; CORONARY VESSELS; CULTURE TECHNIQUES; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

SUS;

EID: 61449196879     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.09.027     Document Type: Article

References (57)

1. Antropova Y.G., Bryantsev A.L., Kalinina N.I., Il'inskaya O.P., and Tararak E.M. Proliferative activity and expression of cyclin-dependent kinase inhibitor p21WAF1 and p53 protein in endothelial cells of human aorta during replicative aging in vitro. Bull. Exp. Biol. Med. 134 (2000) 81-83
2. Asai K., Kudej R.K., Shen Y.T., Yang G.P., Takagi G., Kudej A.B., Geng Y.J., Sato N., Nazareno J.B., Vatner D.E., Natividad F., Bishop S.P., and Vatner S.F. Peripheral vascular endothelial dysfunction and apoptosis in old monkeys. Arterioscler. Thromb. Vasc. Biol. 20 (2000) 1493-1499
3. Atochina E.N., Beers M.F., Hawgood S., Poulain F., Davis C., Fusaro T., and Gow A.J. Surfactant protein-D, a mediator of innate lung immunity, alters the products of nitric oxide metabolism. Am. J. Respir. Cell Mol. Biol. 30 (2004) 271-279
4. Bernier S.G., Haldar S., and Michel T. Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase. J. Biol. Chem. 275 (2000) 30707-30715
5. Bourbon J.R., and Chailley-Heu B. Surfactant proteins in the digestive tract, mesentery, and other organs: evolutionary significance. Comp. Biochem. Physiol. A: Mol. Integr. Physiol. 129 (2001) 151-161
6. Braam B., de Roos R., Dijk A., Boer P., Post J.A., Kemmeren P.P., Holstege F.C., Bluysen H.A., and Koomans H.A. Nitric oxide donor induces temporal and dose-dependent reduction of gene expression in human endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 287 (2004) H1977-H1986
7. Brandes R.P., Fleming I., and Busse R. Endothelial aging. Cardiovasc. Res. 66 (2005) 286-294
8. Chen P.L., and Easton A. Apoptotic phenotype alters the capacity of tumor necrosis factor-related apoptosis-inducing ligand to induce human vascular endothelial activation. J. Vasc. Res. 45 (2008) 111-122
9. Crouch E., Persson A., and Chang D. Accumulation of surfactant protein D in human pulmonary alveolar proteinosis. Am. J. Pathol. 142 (1993) 241-248
10. Csiszar A., Ungvari Z., Koller A., Edwards J.G., and Kaley G. Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol. Genomics 17 (2004) 21-30
11. Fisslthaler B., Benzing T., Busse R., and Fleming I. Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. Nitric Oxide 8 (2003) 253-261
12. Flavahan N.A. Atherosclerosis or lipoprotein-induced endothelial dysfunction. Potential mechanisms underlying reduction in EDRF/nitric oxide activity. Circulation 85 (1992) 1927-1938
13. Fournet-Bourguignon M.P., Castedo-Delrieu M., Bidouard J.P., Leonce S., Saboureau D., Delescluse I., Vilaine J.P., and Vanhoutte P.M. Phenotypic and functional changes in regenerated porcine coronary endothelial cells: increased uptake of modified LDL and reduced production of NO. Circ. Res. 86 (2000) 854-861
14. Gardai S.J., Xiao Y.Q., Dickinson M., Nick J.A., Voelker D.R., Greene K.E., and Henson P.M. By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell 115 (2003) 13-23
15. Grumbach I.M., Chen W., Mertens S.A., and Harrison D.G. A negative feedback mechanism involving nitric oxide and nuclear factor kappa-B modulates endothelial nitric oxide synthase transcription. J. Mol. Cell Cardiol. 39 (2005) 595-603
16. Hartshorn K.L., White M.R., Tecle T., Tornoe I., Sorensen G.L., Crouch E.C., and Holmskov U. Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D. Respir. Res. 8 (2007) 9
17. Hoffmann J., Haendeler J., Aicher A., Rossig L., Vasa M., Zeiher A.M., and Dimmeler S. Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli; important role of nitric oxide. Circ. Res. 89 (2001) 709-715
18. Holmskov U., Thiel S., and Jensenius J.C. Collectins and ficolins: humoral lectins of the innate immune defense. Annu. Rev. Immunol. 21 (2003) 547-578
19. Janssen W.J., McPhillips K.A., Dickinson M.G., Linderman D.J., Morimoto K., Xiao Y.Q., Oldham K.M., Vandivier R.W., Henson P.M., and Gardai S.J. Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha. Am. J. Respir. Crit. Care Med. 178 (2008) 158-167
20. Jin Z.G., Wong C., Wu J., and Berk B.C. Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells. J. Biol. Chem. 280 (2005) 12305-12309
21. Joannides R., Haefeli W.E., Linder L., Richard V., Bakkali E.H., Thuillez C., and Luscher T.F. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 91 (1995) 1314-1319
22. 2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells. J. Biol. Chem. 281 (2006) 27335-27345
23. Kingma P.S., and Whitsett J.A. In defense of the lung: surfactant protein A and surfactant protein D. Curr. Opin. Pharmacol. 6 (2006) 277-283
24. Koh K.K., Han S.H., and Quon M.J. Inflammatory markers and the metabolic syndrome: insights from therapeutic interventions. J. Am. Coll. Cardiol. 46 (2005) 1978-1985
25. Krasinski K., Spyridopoulos I., Kearney M., and Losordo D.W. In vivo blockade of tumor necrosis factor-alpha accelerates functional endothelial recovery after balloon angioplasty. Circulation 104 (2001) 1754-1756
26. Lee M.Y.K., Tse H.F., Siu C.W., Zhu S.G., Man R.Y.K., and Vanhoutte P.M. Genomic changes in regenerated porcine coronary arterial endothelial cells. Arterioscler. Thromb. Vasc. Biol. 27 (2007) 2443-2449
27. Leth-Larsen R., Floridon C., Nielsen O., and Holmskov U. Surfactant protein D in the female genital tract. Mol. Hum. Reprod. 10 (2004) 149-154
28. Leth-Larsen R., Garred P., Jensenius H., Meschi J., Hartshorn K., Madsen J., Tornoe I., Madsen H.O., Sorensen G., Crouch E., and Holmskov U. A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D. J. Immunol. 174 (2005) 1532-1538
29. Libby P. The molecular mechanisms of the thrombotic complications of atherosclerosis. J. Intern. Med. 263 (2008) 517-527
30. Lowenstein C.J. Nitric oxide regulation of protein trafficking in the cardiovascular system. Cardiovasc. Res. 75 (2007) 240-246
31. Lüscher T.F., and Noll G. The pathogenesis of cardiovascular disease: role of the endothelium as a target and mediator. Atherosclerosis 118 Suppl. (1995) S81-S90
32. Madsen J., Kliem A., Tornoe I., Skjodt K., Koch C., and Holmskov U. Localization of lung surfactant protein D on mucosal surfaces in human tissues. J. Immunol. 164 (2000) 5866-5870
33. Makino N., Maeda T., Sugano M., Satoh S., Watanabe R., and Abe N. High serum TNF-alpha level in Type 2 diabetic patients with microangiopathy is associated with eNOS down-regulation and apoptosis in endothelial cells. J. Diabetes Complications 19 (2005) 347-355
34. Meyers M.R., and Gokce N. Endothelial dysfunction in obesity: etiological role in atherosclerosis. Curr. Opin. Endocrinol. Diabetes Obes. 14 (2007) 365-936
35. Miyauchi H., Minamino T., Tateno K., Kunieda T., Toko H., and Komuro I. Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway. EMBO J. 23 (2004) 212-220
36. Moncada S., Rees D.D., Schulz R., and Palmer R.M. Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 2166-2170
37. Motwani M., White R.A., Guo N., Dowler L.L., Tauber A.I., and Sastry K.N. Mouse surfactant protein-D: cDNA cloning, characterization, and gene localization to chromosome 14. J. Immunol. 155 (1995) 5671-5677
38. Qiao M., Shapiro P., Kumar R., and Passaniti A. Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway. J. Biol. Chem. 279 (2004) 42709-42718
39. Ross R. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340 (1999) 115-126
40. Rubin H. Cell aging in vivo and in vitro. Mech. Ageing Dev. 98 (1997) 1-35
41. Sack M. Tumor necrosis factor-alpha in cardiovascular biology and the potential role for anti-tumor necrosis factor-alpha therapy in heart disease. Pharmacol. Ther. 94 (2002) 123-135
42. Secchiero P., Gonelli A., Carnevale E., Milani D., Pandolfi A., Zella D., and Zauli G. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 107 (2003) 2250-2256
43. Shi Q., Aida K., Vandeberg J.L., and Wang X.L. Passage-dependent changes in baboon endothelial cells--relevance to in vitro aging. DNA Cell Biol. 23 (2004) 502-509
44. Shimokawa H., Aarhus L.L., and Vanhoutte P.M. Porcine coronary arteries with regenerated endothelium have a reduced endothelium-dependent responsiveness to aggregating platelets and serotonin. Circ. Res. 61 (1987) 256-270
45. Snyder G.D., Oberley-Deegan R.E., Goss K.L., Romig-Martin S.A., Stoll L.L., Snyder J.M., and Weintraub N.L. Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 294 (2008) H2053-H2059
46. Soerensen C.M., Nielsen O.L., Willis A., Heegaard P.M., and Holmskov U. Purification, characterization and immunolocalization of porcine surfactant protein D. Immunology 114 (2005) 72-82
47. Sorensen G.L., Hjelmborg J.V., Leth-Larsen R., Schmidt V., Fenger M., Poulain F., Hawgood S., Sørensen T.I., Kyvik K.O., and Holmskov U. Surfactant protein D of the innate immune defence is inversely associated with human obesity and SP-D deficiency infers increased body weight in mice. Scand. J. Immunol. 64 (2006) 633-638
48. Sorensen G.L., Husby S., and Holmskov U. Surfactant protein A and surfactant protein D variation in pulmonary disease. Immunobiology 212 (2007) 381-416
49. Sorensen G.L., Madsen J., Kejling K., Tornoe I., Nielsen O., Townsend P., Poulain F., Nielsen C.H., Reid K.B., Hawgood S., Falk E., and Holmskov U. Surfactant protein D is proatherogenic in mice. Am. J. Physiol. Heart Circ. Physiol. 290 (2005) H2286-H2294
50. Tschudi M.R., Barton M., Bersinger N.A., Moreau P., Cosentino F., Noll G., Malinski T., and Lüscher T.F. Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery. J. Clin. Invest. 98 (1996) 899-905
51. van Eijk M., Haagsman H.P., Skinner T., Archibald A., Reid K.B., and Lawson P.R. Porcine lung surfactant protein D: complementary DNA cloning, chromosomal localization, and tissue distribution. J. Immunol. 164 (2000) 1442-1450
52. van Eijk M., van de Lest C.H., Batenburg J.J., Vaandrager A.B., Meschi J., Hartshorn K.L., van Golde L.M., and Haagsman H.P. Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers. Am. J. Respir. Cell Mol. Biol. 26 (2002) 739-747
53. Vanhoutte P.M. Endothelial dysfunction and atherosclerosis. Eur. Heart J. 18 (1997) E19-29
54. Vanhoutte P.M. Endothelial control of vasomotor function: from health to coronary disease. Circ. J. 67 (2003) 572-575
55. Vanhoutte P.M., Fournet-Bourguignon M.P., and Vilaine J.P. Dysfonction de la voie du monoxide d'azote au cours de la régénération de l'endothélium coronarien. Académie Nationale de Médecine 186 (2002) 1525-1541
56. Zhang L., Himi T., Morita I., and Murota S. Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity. Cell Death Differ. 8 (2001) 528-536
57. Zhao X.M., Wu Y.P., Wei R., Cai H.X., Tornoe I., Han J.J., Wang Y., de Groot P.G., Holmskov U., Xia Z.L., and Sorensen G.L. Plasma surfactant protein D levels and the relation to body mass index in a Chinese population. Scand. J. Immunol. 66 (2007) 71-76