Escape mutation selected by Gag28-36-specific cytotoxic T cells in HLA-A*2402-positive HIV-1-infected donors

Microbes and Infection

Volumn 11, Issue 2, 2009, Pages 198-204

  Koizumi, Hirokazu ^a   Iwatani, Tomomi ^a   Tanuma, Junko ^b   Fujiwara, Mamoru ^a   Izumi, Taisuke ^a   Oka, Shinichi ^a,b   Takiguchi, Masafumi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Cytotoxic T lymphocytes; Escape; HIV 1

Indexed keywords

EPITOPE; GAG PROTEIN; HLA A ANTIGEN;

ALLELE; ARTICLE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; JAPANESE; LONGITUDINAL STUDY; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

CELLS, CULTURED; EPITOPES, T-LYMPHOCYTE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV INFECTIONS; HIV-1; HLA-A ANTIGENS; HUMANS; MUTATION, MISSENSE; SELECTION (GENETICS); T-LYMPHOCYTES, CYTOTOXIC;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 61449158608     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2008.11.005     Document Type: Article

References (27)

1. Borrow P., Lewicki H., Hahn B.H., Shaw G.M., and Oldstone M.B. Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J. Virol 68 (1994) 6103-6110
2. Koup R.A., Safrit J.T., Cao Y., Andrews C.A., McLeod G., Borkowsky W., Farthing C., and Ho D.D. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol 68 (1994) 4650-4655
3. Ogg G.S., Jin X., Bonhoeffer S., Dunbar P.R., Nowak M.A., Monard S., Segal J.P., Cao Y., Rowland-Jones S.L., Cerundolo Y., Hurley A., Markowitz M., Ho D.D., Nixon D.F., and McMichael A.J. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science 279 (1998) 2103-2106
4. Goulder P.J., Phillips R.E., Colbert R.A., McAdam S., Ogg G., Nowak M.A., Giangrade P., Luzzi G., Morgan B., Edwards A., McMichael A.J., and Rowland-Jones S. Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS. Nat. Med 3 (1997) 212-217
5. Borrow P., Lewicki H., Wei X., Horwitz M.S., Peffer N., Meyers H., Nelson J.A., Gairin J.E., Hahn B.H., Oldstone M.B., and Shaw G.M. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat. Med 3 (1997) 205-211
6. Couillin I., Connan F., Culmann-Penciolelli B., Gomard E., Guillet J.G., and Choppin J. HLA-dependent variations in human immunodeficiency virus Nef protein alter peptide/HLA binding. Eur. J. Immunol 25 (1995) 728-732
7. Kelleher A.D., Long C., Holmes E.C., Allen R.L., Wilson J., Conlon C., Workman C., Shaunak S., Olson K., Goulder P., Brander C., Ogg G., Sullivan J.S., Dyer W., Jones I., McMichael A.J., Rowland-Jones S., and Phillips R.E. Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses. J. Exp. Med 193 (2001) 375-386
8. Price D.A., Goulder P.J., Klenerman P., Sewell A.K., Easterbrook P.J., Troop M., Bangham C.R., and Phillips R.E. Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 1890-1895
9. Phillips R.E., Rowland-Jones S., Nixon D.F., Gotch F.M., Edwards J.P., Ogunlesi A.O., Elvin J.G., Rothbard J.A., Bangham C.R., Rizza C.R., and McMichael A.J. Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354 (1991) 453-459
10. Fujiwara M., Tanuma J., Koizumi H., Kawashima Y., Honda K., Mastuoka-Aizawa S., Dohki S., Oka S., and Takiguchi M. Different abilities of escape mutant-specific cytotoxic T cells to suppress replication of escape mutant and wild-type human immunodeficiency virus type 1 in new hosts. J. Virol 82 (2008) 138-147
11. Allen T.M., O'Connor D.H., Jing P., Dzuris J.L., Mothe B.R., Vogel T.U., Dunphy E., Libel M.E., Emerson C., Wilson N., Kunsman K.J., Wang X., Allison D.B., Hughes A.L., Desrosiers R.C., Altman J.D., Wolinsky S.M., Sette A., and Watkins D.I. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viremia. Nature 407 (2000) 386-390
12. McMichael A.J., and Rowland-Jones S.L. Cellular immune responses to HIV. Nature 410 (2001) 980-987
13. Barouch D.H., Kunstman J., Kuroda M.J., Schmitz J.E., Santra S., Peyerl F.W., Krivulka G.R., Beaudry K., Lifton M.A., Gorgone D.A., Montefiori D.C., Lewis M.G., Wolinsky S.M., and Letvin N.L. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes. Nature 415 (2002) 335-339
14. Barouch D.H., Kunstman J., Kuroda M.J., Schmitz J.E., Santra S., Peyerl F.W., Krivulka G.R., Beaudry K., Lifton M.A., Gorgone D.A., Montefiori D.C., Lewis M.G., Wolinsky S.M., and Letvin N.L. Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys. J. Virol 77 (2003) 7367-7375
15. Walker B.D., and Korber B.T. Immune control of HIV: the obstacles of HLA and viral diversity. Nat. Immunol 2 (2001) 473-475
16. Kiepiela P., Ngumbela K., Thobakgale C., Ramduth D., Honeyborne I., Moodley E., Reddy S., de Pierres C., Mncube Z., Mkhwanazi N., Bishop K., van der Stok M., Nair K., Khan N., Crawford H., Payne R., Leslie A., Prado J., Prendergast A., Frater J., McCarthy N., Brander C., Learn G.H., Nickle D., Rousseau C., Coovadia H., Mullins J.I., Heckerman D., Walker B.D., and Goulder P. CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat. Med 13 (2007) 46-53
17. Feeney M.E., Tang Y., Roosevelt K.A., Leslie A.J., McIntosh K., Karthas N., Walker B.D., and Goulder P.J. Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child. J. Virol 78 (2004) 8927-8930
18. Draenert R., Le Gall S., Pfafferott K.J., Leslie A.J., Chetty P., Brander C., Holmes E.C., Chang S.C., Feeney M.E., Addo M.M., Ruiz L., Ramduth D., Jeena P., Altfeld M., Thomas S., Tang Y., Verrill C.L., Dixon C., Prado J.G., Kiepiela P., Martinez-Picado J., Walker B.D., and Goulder P.J. Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection. J. Exp. Med 199 (2004) 905-915
19. T. Imanishi, T. Akaza, A. Kimura, K. Tokunaga, T. Gojobori, in: K. Tsuji, M. Aizawa, T. Sasazuki (Eds.), Allele and Haplotype Frequencies for HLA and Complement Loci in Various Ethnic Groups, HLA 1991: Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Oxford University Press, Oxford, 1992.
20. Ikeda-Moore Y., Tomiyama H., Ibe M., Oka S., Miwa K., Kaneko Y., and Takiguchi M. Identification of a novel HLA-A24-restricted cytotoxic T-lymphocyte epitope derived from HIV-1 Gag protein. AIDS 12 (1998) 2073-2087
21. Ikeda-Moore Y., Tomiyama H., Miwa K., Oka S., Iwamoto A., Kaneko Y., and Takiguchi M. Identification and characterization of multiple HLA-A24-restricted HIV-1 CTL epitopes: strong epitopes are derived from V regions of HIV-1. J. Immunol 159 (1997) 6242-6252
22. Yokomaku Y., Miura H., Tomiyama H., Kawana-Tachikawa A., Takiguchi M., Kojima A., Nagai Y., Iwamoto A., Matsuda Z., and Ariyoshi K. Impaired processing and presentation of cytotoxic-T-lymphocyte (CTL) epitopes are major escape mechanism from CTL immune pressure in human immunodeficiency virus type 1 infection. J. Virol 78 (2004) 1324-1332
23. Karaki S., Kariyone A., Kato N., Iwakura Y., and Takiguchi M. HLA-B51 transgenic mice as recipients for production of polymorphic anti-HLA-A, B-specific antibodies. Immunogenetics 37 (1993) 139-142
24. Okamoto M., Makino M., Kitajima I., Maruyama I., and Baba M. HIV-1-infected myelomonocytic cells are resistant to Fas-mediated apoptosis: effect of tumor necrosis factor-alpha on their Fas expression and apoptosis. Med. Microbiol. Immunol 186 (1997) 11-17
25. Altman J.D., Moss P.A.H., Goulder P.J.R., Barouch D.H., McHeyzer-Williams M.G., Bell J.I., McMichael A.J., and Davis M.M. Phenotype analysis of antigen-specific T lymphocytes. Science 274 (1996) 94-96
26. Maier R., Falk K., Rotzschke O., Maier B., Gnau V., Stevanovic S., Jung G., Rammensee H.G., and Meyerhans A. Peptide motifs of HLA-A3, -A24, and -B7 molecules as determined by pool sequencing. Immunogenetics 44 (1994) 306-308
27. Ibe M., Ikeda-Moore Y., Miwa K., Kaneko Y., Yokota S., and Takiguchi M. Role of strong anchor residues in the effective binding of 10-mer and 11-mer peptides to HLA-A*2402 molecules. Immunogenetics 44 (1996) 233-241